Fig. 1 · Structure
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tert-Butyl N-({3-aminobicyclo1.1.1pentan-1-yl}methyl)carbamate
PROTAC Linker
tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate functions as a PROTAC linker, facilitating the design and synthesis of targeted protein degraders. This compound plays a crucial role in the construction of PROTACs, enabling selective degradation of protein targets via the ubiquitin-proteasome system. Researchers can utilize this reagent in various applications involving targeted protein modulation and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1630906-49-8 |
| Applications | PROTAC Linker |
| Formula | C11H20N2O2 |
| Molecular Weight | 212.29 |
| SMILES | O=C(OC(C)(C)C)NCC12CC(N)(C1)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.