Fig. 1 · Structure

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tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate

PROTAC Linker

tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate is a novel PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). It serves as a critical component in the development of bifunctional molecules, promoting targeted degradation of specific proteins within cells. This reagent is essential for researchers focused on protein modulation and therapeutic interventions in various diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 172348-63-9
Applications PROTAC Linker
Formula C13H25NO3
Molecular Weight 243.35
SMILES
C(NC(OC(C)(C)C)=O)[C@@H]1CC[C@@H](CO)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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