Fig. 1 · Structure
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Methyl 3-aminobicyclo1.1.1pentane-1-carboxylate
PROTAC Linker
Methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of bifunctional small molecules designed for targeted protein degradation. This compound enables effective conjugation between target proteins and ligands, promoting ubiquitination and cellular degradation pathways. Its application is crucial in research focused on protein homeostasis, cellular regulation, and therapeutic discovery in diseases associated with protein misfolding and dysfunction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 758684-88-7 |
| Applications | PROTAC Linker |
| Formula | C7H11NO2 |
| Molecular Weight | 141.17 |
| SMILES | O=C(OC)C12CC(N)(C1)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.