Fig. 1 · Structure
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Cbz-PEG2-C2-NH2
PROTAC Linker
Cbz-PEG2-C2-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) structure enhances solubility and biocompatibility, making it suitable for applications in targeted protein degradation studies. Researchers utilize this linker to create more effective PROTACs that can selectively induce the ubiquitination and degradation of specific proteins, thereby advancing drug discovery and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 169744-02-9 |
| Applications | PROTAC Linker |
| Formula | C14H22N2O4 |
| Molecular Weight | 282.34 |
| SMILES | O=C(OCC=1C=CC=CC1)NCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.