Fig. 1 · Structure
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3-(1-{(9h-fluoren-9-yl)methoxycarbonyl}piperidin-4-yl)propanoic acid
PROTAC Linker
3-(1-{[(9h-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)propanoic acid serves as a versatile PROTAC linker, facilitating the assembly of targeted protein degradation agents. Its structure enables the effective conjugation of ligand pairs, promoting selective degradation of target proteins via the ubiquitin-proteasome system. This reagent is instrumental in the development of innovative therapeutic strategies for various diseases, including cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 154938-68-8 |
| Applications | PROTAC Linker |
| Formula | C23H25NO4 |
| Molecular Weight | 379.46 |
| SMILES | O=C(O)CCC1CCN(C(=O)OCC2C=3C=CC=CC3C=4C=CC=CC42)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.