Fig. 1 · Structure

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Piperazine-CH2-propargyl

PROTAC Linker

Piperazine-CH2-propargyl is a versatile PROTAC linker designed for the synthesis of protein-targeting chimeras. It facilitates targeted protein degradation by connecting a ligand to an E3 ligase recruiting component, enabling selective degradation of specific proteins. This compound is essential for researchers aiming to develop novel PROTACs for therapeutic applications in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 911398-04-4
Applications PROTAC Linker
Formula C8H14N2
Molecular Weight 138.21
SMILES
C#CCCN1CCNCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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