Fig. 1 · Structure
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Methyl 4-(piperidin-4-ylmethyl)benzoate hydrochloride
PROTAC Linker
Methyl 4-(piperidin-4-ylmethyl)benzoate hydrochloride is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation strategies by facilitating the effective assembly of the targeting and degradation components. Its application is crucial in various research areas, including drug discovery and development, particularly for the modulation of specific protein levels within cellular environments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 333986-70-2 |
| Applications | PROTAC Linker |
| Formula | C14H20ClNO2 |
| Molecular Weight | 269.77 |
| SMILES | Cl.O=C(OC)C1=CC=C(C=C1)CC2CCNCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.