4-Azide-TFP-amide-PEG4-acid

Catalog No.: A94952
Biochemical Assay Reagent
4-Azide-TFP-amide-PEG4-acid is a biochemical assay reagent designed for efficient conjugation reactions. Featuring an aryl azide that can be photo-activated under UV light (250 to 350 nm), it facilitates the covalent attachment to various biomolecules. The inclusion of a PEG spacer enhances aqueous solubility and minimizes steric hindrance during ligation, while the carboxylic acid moiety allows for amine reactions in the presence of an activator to generate stable amide bonds. This reagent is suitable for applications in bioconjugation chemistry and the development of novel biosensors.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description4-Azide-TFP-amide-PEG4-acid is a biochemical assay reagent designed for efficient conjugation reactions. Featuring an aryl azide that can be photo-activated under UV light (250 to 350 nm), it facilitates the covalent attachment to various biomolecules. The inclusion of a PEG spacer enhances aqueous solubility and minimizes steric hindrance during ligation, while the carboxylic acid moiety allows for amine reactions in the presence of an activator to generate stable amide bonds. This reagent is suitable for applications in bioconjugation chemistry and the development of novel biosensors.
Product Information
Catalog NumA94952
FormulaC18H22F4N4O7
Molecular Weight482.38
CAS Number2566404-74-6
SMILES[N-]=[N+]=NC1=C(C(F)=C(C(F)=C1F)C(NCCOCCOCCOCCOCCC(O)=O)=O)F
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