Methyltetrazine-PEG11-DBCO is a TCO-reactive reagent featuring a DBCO group and a hydrophilic PEG spacer. This compound enables the efficient conversion of azide-containing peptides or proteins into tetrazine-modified analogs without the need for catalysts or auxiliary reagents. The DBCO moiety is particularly beneficial for facilitating copper-free Click Chemistry reactions, making this reagent valuable for biochemical assays and labeling applications in chemical biology and therapeutic research.
Methyltetrazine-PEG11-DBCO is a TCO-reactive reagent featuring a DBCO group and a hydrophilic PEG spacer. This compound enables the efficient conversion of azide-containing peptides or proteins into tetrazine-modified analogs without the need for catalysts or auxiliary reagents. The DBCO moiety is particularly beneficial for facilitating copper-free Click Chemistry reactions, making this reagent valuable for biochemical assays and labeling applications in chemical biology and therapeutic research.
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