TCO-PEG4-TFP ester

Catalog No.: A93865
Biochemical Assay Reagent
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent, primarily targeting amine-containing biopolymers such as proteins and antibodies. The inclusion of 2,3,5,6-tetrafluorophenol (TFP) provides enhanced hydrolytic stability in aqueous environments, leading to more efficient and reproducible labeling processes. TFP esters react with primary amines to form covalent amide bonds at rates comparable to NHS esters, making this reagent valuable for biochemical assays and various protein modification applications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionTCO-PEG4-TFP Ester is an amine-reactive labeling reagent, primarily targeting amine-containing biopolymers such as proteins and antibodies. The inclusion of 2,3,5,6-tetrafluorophenol (TFP) provides enhanced hydrolytic stability in aqueous environments, leading to more efficient and reproducible labeling processes. TFP esters react with primary amines to form covalent amide bonds at rates comparable to NHS esters, making this reagent valuable for biochemical assays and various protein modification applications.
Product Information
Catalog NumA93865
FormulaC26H35F4NO8
Molecular Weight565.55
CAS Number2268817-73-6
SMILESO=C(NCCOCCOCCOCCOCCC(OC1=C(F)C(F)=CC(F)=C1F)=O)OC2CC/C=C\CCC2
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