Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
DBCO-PEG3-amine is a PEG-based linker designed for use in PROTAC synthesis. This compound features a DBCO group, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its application in the development of bifunctional degraders positions DBCO-PEG3-amine as a valuable tool in chemical biology research, particularly for targeted protein degradation studies. -
PROTAC Linkers
DNP-PEG4-DBCO is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This compound serves as a click chemistry reagent, featuring a DBCO group that participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its unique properties make it suitable for developing targeted protein degradation strategies in various biological research applications. -
PROTAC Linkers
DBCO-PEG2-acid is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. Featuring a DBCO group, it enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is essential for the development of targeted protein degradation strategies in chemical biology research. Its ability to form stable linkages enhances the design and application of bifunctional molecules for therapeutic development. -
Protein degrader
Tri-GalNAc-DBCO is a synthetic ligand featuring three GalNAc units linked to DBCO, designed for use in protein degradation applications. It selectively targets the asialoglycoprotein receptor (ASGPR), facilitating the delivery of conjugated proteins or small molecules to lysosomes via receptor-mediated endocytosis. This targeted approach allows for the effective degradation of substrates, making Tri-GalNAc-DBCO a valuable tool in research focusing on lysosomal-targeted therapeutics and protein modulation strategies. -
PROTAC Linker
DBCO-PEG4-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing molecules, allowing for precise bioconjugation. Its application is critical in the development of targeted protein degradation strategies, enhancing the ability to study protein interactions and manipulate cellular processes. -
PROTAC Linker
DBCO-Biotin is a PROTAC linker featuring an alkyl chain structure that facilitates the synthesis of PROTACs. As a click chemistry reagent, it contains a DBCO moiety that efficiently undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This property makes DBCO-Biotin a valuable tool in targeted protein degradation research, allowing for the precise construction of bifunctional compounds necessary for therapeutic development. -
Click Chemistry Reagent
Halo-DBCO is a click chemistry reagent featuring dibenzocyclooctyne (DBCO) that serves as a highly efficient ligand for HaloTag proteins. This compound facilitates the formation of covalent bonds between HaloTag and DBCO, enabling precise labeling and functionalization of biomolecules. Halo-DBCO is valuable in applications such as protein visualization, targeted drug delivery, and biosensing, making it a critical tool in chemical biology and bioconjugation studies. -
PROTAC Linker
DBCO-PEG12-NHS ester is a PEG-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It features a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) to azide-containing molecules, enabling precise conjugation. This reagent is essential for researchers developing PROTACs aimed at targeted protein degradation, thereby enhancing insights in various biological processes and therapeutic applications. -
PROTAC Linkers
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker designed for effective synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a dibenzocyclooctyne (DBCO) moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is widely utilized in chemical biology research for targeted protein degradation and the development of novel therapeutic agents. -
PROTAC Linker
DBCO-S-S-PEG3-biotin is a PEG-based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). This compound features a DBCO moiety that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, facilitating efficient conjugation. Its biotin component enhances detection and purification of PROTACs, making it a valuable tool for biological research focused on targeted protein degradation. -
PROTAC linker
N-DBCO-N-bis(PEG2-C2-NHS ester) serves as a versatile PROTAC linker, facilitating the assembly of PROTACs for targeted protein degradation. This PEG-based compound features a DBCO moiety, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its unique structure enhances solubility and biocompatibility, making it a valuable tool in chemical biology research and drug development applications. -
PROTAC Linkers
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based linker designed for the synthesis of PROTACs. This reagent features a DBCO group that allows for efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its biotin component enhances labeling and purification processes, making it valuable in target protein degradation studies and other biochemical applications. -
PROTAC Linker
DBCO-PEG5-GGG-NH2 is a versatile PROTAC linker that facilitates the creation of proteolysis-targeting chimeras (PROTACs). This compound efficiently connects target proteins with E3 ligases, enabling the modulation of protein degradation pathways. Its application in synthetic biology allows researchers to explore targeted protein degradation strategies for therapeutic interventions. -
PROTAC Linkers
DBCO-NHCO-PEG2-Biotin is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a DBCO (dibenzylcyclooctyne) group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its biotin component enhances the attachment of PROTACs to target proteins, facilitating studies on targeted protein degradation and cellular dynamics. DBCO-NHCO-PEG2-Biotin is essential for research applications involving targeted therapeutic strategies and the exploration of protein interactions. -
PROTAC Linkers
DBCO-PEG9-amine is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring a DBCO moiety, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound enables precise and efficient conjugation strategies, making it valuable for applications in targeted protein degradation research. -
PROTAC Linkers
DBCO-PEG6-amine is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features a DBCO group, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This versatile reagent facilitates the construction of bifunctional molecules for targeted protein degradation studies, enhancing research in cellular regulation and therapeutic development. -
PROTAC Linkers
DBCO-PEG1-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring a DBCO moiety, this compound facilitates efficient click chemistry through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. DBCO-PEG1-acid is integral for developing targeted degradation strategies in protein research, enabling precise modulation of protein levels for various biological applications. -
PROTAC Linkers
HyNic-PEG2-DBCO is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its efficient click chemistry properties enable precise conjugation, making it valuable for studies in targeted protein degradation and therapeutic development. Applications of HyNic-PEG2-DBCO include the creation of custom PROTACs for probing biological pathways and evaluating protein interactions. -
PROTAC Linkers
DBCO-PEG5-acid is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Its primary mechanism involves the DBCO group, which enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound is essential for facilitating site-specific conjugation in PROTAC development, contributing to targeted protein degradation in cellular research and therapeutic applications. -
PROTAC Linker
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This reagent features a DBCO moiety that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, facilitating targeted protein degradation. Its unique properties make it valuable for applications in chemical biology and drug discovery. -
PROTAC Linkers
Bromoacetyl-PEG3-DBCO is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features a dibenzylcyclooctyne (DBCO) group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It plays a critical role in the development of targeted protein degradation strategies, facilitating the formation of highly functionalized PROTACs for various biological research applications. -
PROTAC Linkers
DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker specifically designed for the synthesis of PROTACs. Its DBCO group facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. This compound is instrumental in the development of targeted protein degradation strategies, enhancing research in cancer therapy and other therapeutic areas. -
PROTAC Linkers
m-PEG4-NH-DBCO is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a dibenzocyclooctyne (DBCO) moiety, enabling effective strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its properties facilitate the development of targeted protein degradation strategies in chemical biology research, positioning m-PEG4-NH-DBCO as a valuable tool for advancing PROTAC technology. -
PROTAC Linker
DBCO-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for proteolysis-targeting chimeras (PROTACs). This compound effectively facilitates the development of PROTACs by allowing for the conjugation of ligands, enhancing target specificity and degradation efficiency. It is ideal for research applications focusing on targeted protein degradation and the modulation of protein levels in cellular assays. -
PROTAC Linkers
DBCO-C-PEG1 is a PEG-based linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). It features a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent enables precise conjugation and enhances the development of targeted protein degradation studies, contributing to advancements in therapeutic applications and cellular biology research. -
PROTAC Linker
DBCO-C2-SulfoNHS ester serves as a key PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound incorporates a DBCO moiety that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners. It plays a crucial role in the development of targeted protein degradation strategies in chemical biology research. -
PROTAC Linker
DBCO-NH-Boc is a PROTAC linker featuring a dibenzocyclooctyne (DBCO) moiety that enables efficient synthesis of PROTACs through click chemistry. This compound facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, providing a versatile approach for targeted protein degradation research. Its unique structure enhances connectivity and stability, making it suitable for various applications in chemical biology and drug discovery. -
PROTAC Linkers
DBCO-PEG2-amine is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features a dibenzocyclooctyne (DBCO) moiety that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. DBCO-PEG2-amine facilitates the development of PROTACs for targeted protein degradation applications, making it valuable in chemical biology and therapeutic research. -
PROTAC Linkers
DBCO-PEG1-amine is a polyethylene glycol (PEG) based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a dibenzocyclooctyne (DBCO) functional group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. DBCO-PEG1-amine enhances the modularity and functionality of PROTACs, making it instrumental in targeted protein degradation research and therapeutic applications. -
PROTAC Linker
DBCO-PEG1 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is crucial for the development of targeted protein degradation strategies in chemical biology research, facilitating the efficient assembly of bifunctional small molecules for therapeutic applications. -
PROTAC Linkers
DBCO-PEG9-DBCO is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features a DBCO ( dibenzocyclooctyne) moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its ability to create covalent bonds enhances the stability and efficacy of PROTACs, making it a valuable tool for targeted protein degradation studies and drug discovery applications. -
PROTAC linker
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based linker that facilitates the synthesis of PROTACs by incorporating a DBCO moiety that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This linker allows for the precise modification of biomolecules, enhancing their stability and solubility. It is particularly useful in the development of targeted protein degradation strategies and other chemical biology applications involving conjugation techniques. -
PROTAC Linkers
DBCO-PEG8-acid is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. The compound features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its high level of biocompatibility and efficient conjugation properties make it suitable for various applications in chemical biology and therapeutic development. -
PROTAC Linkers
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling the efficient formation of covalent linkages. Its application in PROTAC development supports targeted protein degradation studies, making it a valuable tool in chemical biology and drug discovery research. -
PROTAC Linkers
DBCO-PEG4-NH-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring a DBCO functional group, this compound facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. Its primary application lies in the development of targeted protein degradation strategies, making it valuable in research focused on cellular regulation and therapeutic development. -
PROTAC Linkers
DBCO-PEG1-NH-Boc is a PEG-based linkerso designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features a dibenzocyclooctyne (DBCO) functional group, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing biomolecules. This reagent is integral in developing targeted protein degradation strategies, facilitating the specific modulation of protein levels in cellular studies. -
PROTAC Linkers
DBCO-PEG12-acid is a polyethylene glycol (PEG)-based linker utilized in the synthesis of Proteolysis Targeting Chimera (PROTAC) molecules. Featuring a DBCO ( dibenzocyclooctyne) moiety, it enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is integral for developing novel bifunctional agents aimed at targeted protein degradation, enhancing research in pharmacology and therapeutic applications. -
PROTAC Linkers
DBCO-PEG2-PFP ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enhancing the efficiency of target protein degradation. Its application in PROTAC development makes it a valuable tool for researchers exploring regulated protein degradation pathways in cellular studies. -
PROTAC Linkers
DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound features a dibenzocyclooctyne (DBCO) moiety, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. DBCO-PEG2-NH-Boc facilitates the construction of complex bioconjugates, making it a valuable tool for targeted protein degradation studies in chemical biology and drug discovery. -
PROTAC Linker
DBCO-NHCO-PEG5-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. Its unique properties make it suitable for applications in targeted protein degradation research and the development of novel therapeutic strategies. -
PROTAC Linkers
DBCO-NH-(CH2)4COOH is a Proximity-Activated Linker (PROTAC) that facilitates targeted protein degradation by linking target proteins to E3 ligases. This compound features a DBCO functional group, which enables efficient reaction through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its use in PROTAC synthesis supports research in protein modulation and therapeutic development, providing a versatile tool for advancing insights in cellular biology and drug discovery. -
Click Chemistry Reagent
DBCO-amine is a click chemistry reagent featuring a dibenzocyclooctyne (DBCO) group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound is instrumental in the synthesis of antibody-drug conjugates (ADCs), providing a targeted approach for delivering therapeutics. Its utility extends to various applications in chemical biology, including bioconjugation and the development of precision medicine strategies. -
Click Chemistry Reagent
DBCO-acid is a click chemistry reagent that features a DBCO (dibenzocyclooctyne) moiety, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is essential for the synthesis of antibody-drug conjugate (ADC) linkers, such as DBCO-NHS ester and DBCO-PEG-MMAE. DBCO-acid facilitates the formation of agent-linker conjugates, providing researchers with robust tools for bioconjugation applications in drug delivery and molecular labeling. -
Biotinylation Reagent
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin conjugate designed for biotinylation applications. This reagent facilitates the introduction of a biotin moiety to azide-tagged biomolecules through copper-free strain-promoted alkyne-azide cycloaddition (SPAAC). DBCO-PEG4-Biotin is particularly valuable in applications involving protein labeling, detection, and purification, enhancing the study of biomolecular interactions and cellular processes. Its PEG components improve solubility and stability, making it an essential tool in chemical biology research. -
DBCO Iridium Catalyst
DBCO Iridium Catalyst functions as a powerful tool for in situ labeling and imaging of biomolecules, including proteins and nucleic acids, in living organisms. Its unique DBCO labeling capability enhances the specificity and efficiency of targeted drug delivery systems. This catalyst is essential for researchers investigating biomolecular interactions and developing advanced imaging techniques in biological systems. -
Biochemical Assay Reagent
Trivalent GalNAc-DBCO is a versatile biochemical assay reagent designed for efficient oligonucleotide coupling. It facilitates the bioconjugation of GalNAc moieties to oligonucleotides, enhancing targeting and delivery capabilities in nucleic acid research. This compound is particularly useful in developing targeted therapeutic strategies and studying oligonucleotide interactions within biological systems. -
Biochemical Assay Reagent
DBCO-Tetraacetyl mannosamine is a click chemistry reagent featuring a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound is primarily employed in biochemical assays for the modification of glycoproteins and cell surface molecules, enabling applications in biomarker discovery and purification. Furthermore, it serves as a drug carrier in controlled release systems, making it a valuable tool for advancing research in bioconjugation and drug delivery mechanisms. -
Biochemical Reagent
DSPE-PEG-DBCO ammonium is a biochemical reagent that facilitates copper-free click chemistry via strain-promoted alkyne-azide cycloaddition (SPAAC) with azido-functionalized peptide ligands. This compound is pivotal in drug delivery and nanoparticle research, enabling precise biomolecule conjugation and enhancing therapeutic efficacy. Its unique properties make it suitable for various applications in bioconjugation and nanomedicine. -
Biochemical Reagent
DBCO-Palmitic is a reactive biochemical reagent that functions as a click chemical under the azide-alkyne cycloaddition mechanism. This compound is particularly useful for labeling and modifying biomolecules through SPAAC reactions, facilitating the study of various biological processes. Its applications include bioconjugation methods and tracking of molecular interactions in live-cell imaging. -
Click chemistry intermediate
DBCO-Sulfo-Link-biotin TEA serves as a click chemistry intermediate featuring a dibenzocyclooctyne (DBCO) group, enabling efficient ring strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is primarily used for bioconjugation applications, facilitating the labeling of biomolecules with biotin for downstream interactions and assays. Its high specificity and reactivity make it valuable in chemical biology and protein engineering studies.
