DBCO-Biotin is a PROTAC linker featuring an alkyl chain structure that facilitates the synthesis of PROTACs. As a click chemistry reagent, it contains a DBCO moiety that efficiently undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This property makes DBCO-Biotin a valuable tool in targeted protein degradation research, allowing for the precise construction of bifunctional compounds necessary for therapeutic development.
DBCO-Biotin is a PROTAC linker featuring an alkyl chain structure that facilitates the synthesis of PROTACs. As a click chemistry reagent, it contains a DBCO moiety that efficiently undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This property makes DBCO-Biotin a valuable tool in targeted protein degradation research, allowing for the precise construction of bifunctional compounds necessary for therapeutic development.
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