Fig. 1 · Structure
Documents & Downloads
DBCO-PEG3-amine
PROTAC Linker
DBCO-PEG3-amine is a PEG-based linker designed for use in PROTAC synthesis. This compound features a DBCO group, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its application in the development of bifunctional degraders positions DBCO-PEG3-amine as a valuable tool in chemical biology research, particularly for targeted protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2093409-57-3 |
| Applications | PROTAC Linker |
| Formula | C27H33N3O5 |
| Molecular Weight | 479.57 |
| SMILES | NCCOCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.