Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Dehydroacetic acid sodium is a pyrone derivative known for its fungicidal properties. It exhibits antibacterial and antifungal activity, making it valuable for applications in microbial control in various settings. Additionally, dehydroacetic acid demonstrates phytotoxic effects, indicating its potential use in agricultural research. -
Antibacterial Agent
Chlorhexidine diacetate is a cationic antimicrobial agent that primarily targets microbial cell membranes. Its mechanism involves non-specific binding to membrane phospholipids, leading to structural disruption and leakage of cellular contents. Chlorhexidine diacetate exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria, making it valuable for applications in microbiology and infection control. Additionally, it can adversely affect membrane permeability, resulting in protein precipitation and metabolic disturbances, which contribute to rapid microbial growth inhibition and induction of cell death. -
Antibacterial Agent
5,7-Dihydroxy-4-methylcoumarin is a coumarin derivative known for its antibacterial properties. This compound exhibits significant antifungal and antibacterial activities, making it valuable for research in microbial inhibition. Its potential applications include studying mechanisms of action against various pathogens and developing new antimicrobial agents. -
Antibacterial Agent
D-Gluconic acid calcium hydrate is a carboxylic acid known for its antibacterial and chelating properties. It plays a significant role in inhibiting bacterial growth and is commonly used in various biomedical and pharmaceutical research applications. Its ability to complex with metal ions makes it valuable for studies involving metal ion regulation and antimicrobial effectiveness. -
Bacterial Inhibitor
Sodium citrate dihydrate is a bacterial inhibitor that acts by disrupting cellular processes in bacteria. This compound exhibits antibacterial, anti-tumor, and antioxidant activities, demonstrating potential in both microbial and cancer research applications. It can be utilized as a cosolvent or buffer in various biochemical assays, facilitating enhanced stability and solubility of target compounds. -
Antibiotics
Fluconazole hydrate is a triazole antifungal agent that targets fungal cell membrane synthesis by inhibiting the enzyme lanosterol 14-alpha-demethylase. It exhibits significant efficacy against a range of superficial and systemic fungal infections, making it a critical tool in the treatment and prevention of candidiasis and cryptococcosis. Fluconazole hydrate is widely utilized in clinical research to explore antifungal resistance mechanisms and assess therapeutic strategies in various fungal pathogens. -
Anti-Fungal Agent
Enactin Va is an anti-fungal agent derived from the strain of Streptomyces roseoviridis. It exhibits mild antifungal activity, making it suitable for research applications aimed at exploring antifungal properties and mechanisms of action. This compound can be utilized in studies focused on the development of novel antifungal therapies and the assessment of fungal resistance. -
Antifungal Agent
Cryptosporiopsin A is a polyketide that acts as an antifungal agent, demonstrating significant motility inhibitory and lytic activities against the zoospores of Plasmopara viticola, the pathogen responsible for grapevine downy mildew. This compound is valuable for research applications focused on understanding fungal biology and developing innovative antifungal strategies. -
Antimicrobial Agent
Octacosamicin B is an antimicrobial agent that exhibits activity against yeast and filamentous fungi. While its efficacy against bacteria is limited, it serves as a valuable tool in the study of antifungal mechanisms and the development of new antifungal therapies. This compound is useful in various research applications focused on microbial resistance and antifungal activity. -
Antibiotic
(S)-Dihydroaeruginoic acid is an antibiotic derived from Pseudomonas fluorescens, targeting various microbial pathogens. It exhibits substantial antimicrobial activity against a range of fungi, including Rhizoctonia solani, Phytophthora ultimum, Botrytis cinerea, Sclerotium rolfsii, Colletotrichum gloeosporioides, Fusarium oxysporum, and Septoria tritici, as well as against bacterial strains such as Bacillus subtilis, Erwinia herbicola, and Streptomyces albus when assessed at a concentration of 200 μg/disc. This compound is valuable for research focused on antibiotic development and the study of microbial resistance. -
Antibiotic
Verlamelin is a depsipeptide antibiotic that targets and disrupts cellular processes in fungi. It exhibits significant antifungal activity against various plant pathogens, making it a valuable tool for research into plant disease management and fungal biology. Its unique mechanism of action can be explored for insights into antibiotic resistance and the development of new antifungal therapies. -
Antifungal Antibiotic
Mucidin is an antifungal antibiotic that primarily targets the cytochrome bc1 complex within the mitochondrial respiratory chain, inhibiting electron-transfer reactions. This mechanism disrupts ATP production in fungi, leading to their growth inhibition. Mucidin is useful in research applications focused on fungal pathogenesis and mitochondrial function, providing insights into antifungal resistance and treatment strategies. -
Anti-Fungal Agent
Clavamycin A functions as a potent anti-fungal agent, exhibiting significant activity against Candida species. Its antifungal mechanism is characterized by substantial effectiveness that can be antagonized by the presence of dipeptides or tripeptides, while amino acids do not interfere with its action. Notably, Clavamycin A demonstrates no antibacterial properties and does not inhibit β-lactamase activity. This compound is valuable in studying fungal infections and antifungal resistance mechanisms. -
Antifungal Agent
Amphocil is an equimolar mixture of Amphotericin B and cholesteryl sulfate, serving as a potent antifungal agent. It demonstrates significant antifungal activity, making it particularly relevant for research focused on disseminated cryptococcosis. This formulation enhances the efficacy of Amphotericin B, thereby supporting investigations into treatment strategies for this invasive fungal infection. -
Anti-Bacterial Agent
Cephemimycin is an antibacterial agent that exhibits modest activity against bacterial and fungal pathogens. This compound is primarily utilized in research focused on antimicrobial resistance and the development of new antibiotic therapies. Its spectrum of activity may provide insights into the mechanisms of bacterial inhibition and inform further studies in pharmacology and microbiology. -
Antifungal Agent
Tetrahydroechinocandin B is a potent antifungal agent that primarily inhibits 1,3-beta-D-glucan synthesis, exhibiting an IC50 value of 0.85 μg/mL. This mechanism of action disrupts fungal cell wall integrity, making it effective against various fungal pathogens. Tetrahydroechinocandin B is commonly utilized in research applications aimed at understanding antifungal mechanisms and developing therapeutic strategies against fungal infections. -
Anti-Fungal Agent
Crocacin B is an anti-fungal agent that exhibits significant activity against both yeast and filamentous fungi. It has been shown to inhibit mouse fibroblast cells (L929), demonstrating its potential cytotoxic effects. Additionally, Crocacin B disrupts the bc1 segment of electron transport in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome b reduction spectrum. This compound may serve as a valuable tool in fungal research and related applications. -
Antibiotic
Oudemansin A is an antibiotic that targets fungal pathogens by inhibiting protein, RNA, and DNA synthesis. This compound demonstrates significant antifungal activity, making it a valuable reagent in research focused on the mechanisms of fungal infection and resistance. Its efficacy in disrupting essential cellular processes highlights its potential for exploring new therapeutic approaches in mycology. -
Antimicrobial Agent
Scorodonin is an antimicrobial agent that exhibits potent antibacterial and antifungal activities, particularly against Streptomyces species. It functions by inhibiting DNA-dependent RNA polymerases, demonstrating an IC50 of 25 μg/mL. This compound may be utilized in research applications focused on microbial resistance, the characterization of RNA polymerase activity, and the development of new antimicrobial agents. -
Anti-Fungal Agent
Neoenactin M2 is an anti-fungal agent that exhibits potent activity against both yeast-like and filamentous fungi. Its mechanism involves disrupting fungal cell membrane integrity, leading to cell death. This compound is valuable for research applications focused on fungal pathogenesis, drug resistance studies, and the development of antifungal therapies. -
Anti-Fungal Agent
Cyclopaldic acid is a potent anti-fungal agent that effectively inhibits spore germination in Garlic botrytis, demonstrating an inhibition rate of 95%-100% at a concentration of 2.5 μg/mL. This compound is valuable for research in fungal biology and plant pathology, providing insights into fungal inhibition mechanisms and potential agricultural applications. -
Phytotoxin
Zinniol is a penta-substituted benzene phytotoxin primarily associated with various phytopathogenic fungi. It has been identified in sunflower tissues during the early stages of infection, suggesting a role in the pathogenesis of sunflower diseases. This compound serves as a valuable tool for research into plant-fungal interactions and the biochemical mechanisms underlying plant diseases. -
Antimicrobial Agent
Darlucin B is an antimicrobial agent exhibiting potent antibacterial and antifungal activity while demonstrating weak cytotoxicity. It is primarily utilized in research applications focused on developing new antimicrobial therapies and understanding microbial resistance mechanisms. Its diverse biological activity makes it a valuable tool in the field of infectious disease research. -
Macrocyclic dilactone
De-N-methylpamamycin-593B is a macrocyclic dilactone characterized by its 16-membered ring structure. This compound exhibits Aerial Mycelium-inducing activity, making it a valuable tool for the study of fungal development and morphology. Its unique properties facilitate research into microbial fermentation processes and the regulation of secondary metabolism in various organisms. -
1,3-β-D-glucan Synthase Inhibitor
L 705589 is an inhibitor of 1,3-β-D-glucan synthase, targeting the synthesis of key structural components in the fungal cell wall. This semi-synthetic penicillin-type antifungal exhibits potent activity against various Candida species, including Candida albicans and Candida glabrata, with minimum fungicidal concentrations ranging from 0.06 to 8 µg/mL. It demonstrates limited efficacy against Cryptococcus neoformans (MFC: 32 - 64 µg/mL) yet maintains effectiveness against drug-resistant Candida strains and shows a reduced tendency to induce resistance. Additionally, L 705589 has been shown to enhance survival rates in models of minor invasive aspergillosis. -
Antibiotic
Pulvilloric acid is an antifungal antibiotic that specifically targets fungal pathogens. Isolated from the fungus Penicillium pulvillorum, this compound exhibits significant antimicrobial activity, making it valuable in research related to antifungal drug development and microbial resistance studies. Its unique mechanism of action positions it as a critical reagent for investigating fungal infections and developing effective therapeutic strategies. -
Antibiotic
Exfoliazone is a phenoxazine antibiotic that targets fungal organisms, specifically demonstrating efficacy against Valsa ceratosperma. This compound exhibits significant antifungal activity, with an effective dose (ED50) for inhibiting mycelial growth calculated at 70 μg/mL. It serves as a valuable tool for studying fungal resistance mechanisms and exploring potential therapeutic applications in mycology research. -
Antifungal Agent
10-Undecenoic acid (copper) serves as an antifungal agent through its diverse mechanisms of action. It inhibits Aβ oligomerization, scavenges reactive oxygen species (ROS), and suppresses μ-calpain activity, contributing to its neuroprotective effects. Additionally, it demonstrates anticancer properties across various tumor types and effectively inhibits biofilm formation by Candida albicans and infections caused by Methicillin-resistant Staphylococcus aureus (MRSA). Furthermore, 10-Undecenoic acid (copper) disrupts quorum sensing signals in Bacillus subtilis and Pseudomonas aeruginosa, making it a valuable reagent for research in fungal infections and cancer biology. -
Antibiotic
Pyrrolomycin E is a pyrrole antibiotic that exhibits broad-spectrum antibacterial activity. It demonstrates efficacy against both Gram-positive and Gram-negative bacteria, as well as antifungal properties against various fungal strains. This compound is valuable for research applications focused on antibiotic resistance and the development of new antimicrobial agents. -
Antitumor Antibiotic
Glidobactin F is an antitumor antibiotic known for its effectiveness against pathogenic fungi and yeast. This compound demonstrates significant anticancer activity, particularly in enhancing the survival of mice inoculated with P388 leukemia cells. Glidobactin F is valuable for research applications focused on cancer treatment and antifungal studies. -
Secondary Metabolite
Aranorosinol A is a secondary metabolite known for its moderate antibacterial and antifungal activity. This compound is primarily utilized in research applications focused on natural product chemistry and pharmacological screening. Its efficacy against microbial pathogens makes it a valuable candidate for investigating new therapeutic approaches in infectious disease treatments. -
Fungal Inhibitor
Aliconazole is an imidazole derivative that functions as an antifungal agent by inhibiting fungal ergosterol synthesis, which is critical for maintaining cell membrane integrity. This compound exhibits activity against a range of fungal pathogens, making it suitable for applications in mycology research and exploring antifungal mechanisms. Its efficacy in treating fungal infections makes it a valuable reagent for studies focused on antifungal drug development and resistance mechanisms. -
CYP51 Inhibitor
CYP51-IN-30 is a potent inhibitor of CYP51, targeting sterol 14α-demethylase, an essential enzyme in sterol biosynthesis. This compound exhibits significant fungicidal activity, demonstrated by an EC50 value of 2.97 mg/L against Sclerotinia sclerotiorum. Its efficacy makes it a valuable tool for research in antifungal studies and applications in plant pathology. -
Antifungal Agent
Appenolide A is an antifungal furanone compound that derives from the coprophilous fungus Podospora appendiculata. It exhibits significant antifungal activity, making it a valuable tool for studying fungal biology and developing antifungal therapies. Its unique mechanism of action provides insights into fungal resistance and can aid in the discovery of new antifungal agents. -
Antibiotic
β-Prumycin hydrochloride is a carbohydrate antibiotic that exhibits antifungal activity and demonstrates limited antibacterial properties. Its primary application lies in research focused on microbial resistance mechanisms and the development of new antimicrobial therapies. β-Prumycin hydrochloride serves as a valuable tool for studying the interactions between carbohydrates and microbial organisms. -
Antifungal Agent
Rhizocticin A is an antifungal phosphono-oligopeptide that effectively targets fungi such as Ascodesmis, Plicaria, and Rhizoctonia. With a minimum inhibitory concentration (MIC) of 3.5 μg/mL, Rhizocticin A is capable of inhibiting fungal growth by producing the toxic metabolite L-2-Amino-5-phospho-3-cis-pentenoic acid (L-APPA), which disrupts vital cellular metabolism. This compound is valuable for research focused on fungal pathogenesis and the development of antifungal agents. -
Antibiotic
Leucomycin A5 is an antibiotic known for its antifungal activity, effectively targeting various bacterial strains. The minimum inhibitory concentration (MIC) for Staphylococcus pyogenes penicillin-sensitive is 0.8 µg/mL, while Staphylococcus pyogenes penicillin-resistant and Staphylococcus faecalis display MIC values of 3.2 µg/mL and 0.8 µg/mL, respectively. This compound is utilized in research applications focusing on bacterial resistance and the development of novel antimicrobial therapies. -
Lead Compound
3-Amino-1,2,4-triazin-5(2H)-one is a lead compound targeting various biological pathways. This organic triazine derivative exhibits a wide array of biological activities, including antibacterial, antifungal, antiviral, and potential antitumor effects, which are influenced by its chemical structure and functional groups. It serves as a valuable reagent for research applications in pharmacology and medicinal chemistry, facilitating the discovery of new therapeutic agents. -
Antibiotic
Albiducin A is an antibiotic derived from the fungus Hymenoscyphus albidus, known for its antibacterial and anticancer properties. It demonstrates a minimum inhibitory concentration (MIC) range against bacteria and fungi of 16.7-66.7 mg/mL. In cellular assays, Albiducin A exhibits IC50 values of 6.1 μg/mL for mouse fibroblast L929 cells and 2.7 μg/mL for human cervical carcinoma KB3-1 cells. This compound is of significant interest for research in infection and cancer treatment. -
Fungicide
Iprovalicarb is a fungicide that functions by inhibiting fungal growth, targeting specific pathways involved in fungal cell metabolism. This compound is primarily utilized in research focused on fungal diseases, particularly within the winemaking industry. Its effectiveness against various fungal pathogens makes it a valuable tool for studying disease management strategies and developing protective measures in viticulture. -
Antifungal Agent
D13 is an acylhydrazone derivative that exhibits potent antifungal activity. It has demonstrated effectiveness against murine sporotrichosis, making it a valuable candidate for research in fungal infections. Its unique mechanism of action and efficacy profile support its potential applications in the study and treatment of antifungal resistance and related diseases. -
Anti-Fungal Agent
Haliangicin B is an anti-fungal agent primarily targeting filamentous fungi and demonstrating efficacy against oomycetes. This compound exhibits potent biological activity, making it useful for research applications focused on fungal pathogenesis and the development of antifungal therapies. Its selective action excludes antibacterial properties, positioning it specifically within the realm of mycology research. -
Antimicrobial Agent
Terrestribisamide, also known as (E)-N,N′-Diferuloylputrescine, serves as an antimicrobial agent derived from the dried fruits of Tribulus terrestris. This compound exhibits notable antibacterial, antifungal, antioxidant, and anticancer activities, making it a valuable tool for various biological research applications. Its diverse pharmacological properties contribute to its potential in studying microbial resistance and cancer therapies. -
Isomer of Pneumocandin B0
Pneumocandin C0 is an isomer of Pneumocandin B0 known for its antifungal properties. It exhibits significant activity against fungal infections, making it suitable for research in the development of antifungal agents. Derived from the fermentation of Glarea lozoyensis under conditions of high residual fructose concentration, Pneumocandin C0 serves as a valuable compound for studies focusing on fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
BHBM is an aromatic acylhydrazone compound that acts as a potent antifungal agent targeting Cryptococcus neoformans. Its high bactericidal activity makes it a valuable tool for research applications focused on fungal infections and the development of new antifungal therapies. BHBM can be used to explore mechanisms of action and resistance in fungi, contributing to advancements in infectious disease research. -
Antifungal Agent
YZK-C22 is an antifungal agent characterized by its unique 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole framework. It exhibits broad-spectrum fungicidal activity, making it a promising candidate for developing effective antifungal treatments. This compound is suitable for research applications focused on fungal pathogen control and antifungal drug discovery. -
Anti-Fungal Agent
Neocopiamycin B is an antifungal agent derived from the strain Streptomyces hygroscopicus var. crystallogenes. It exhibits potent antifungal activity against various fungal pathogens, making it a valuable tool for studying fungal infections and developing new antifungal therapies. This compound is applicable in research focused on mycology and the exploration of novel antifungal mechanisms. -
Group II introns Inhibitor
Group II intron-IN-1 acts as an inhibitor of fungal Group II introns, demonstrating an IC50 of 3 μM. This compound is valuable for research focusing on fungal infections, particularly those caused by Candida species. Its ability to selectively target intronic processes makes it a significant tool for studying fungal biology and the mechanisms of infection. -
Anti-tubercular Agent
Giparmen is an anti-tubercular agent that demonstrates significant efficacy in targeting Mycobacterium tuberculosis. This compound shows promise for further research into fungal infections, specifically those caused by Candida species. Its unique mechanism and biological activity make it a valuable tool for investigators studying tuberculosis and fungal pathogenesis. -
Antibiotic
Epoformin is a fungal cyclohexene epoxide derived from Diplodia quercivora, primarily acting as an antibiotic. It exhibits inhibitory effects on rye seedling sheath growth and demonstrates notable antifungal activity, particularly against pathogens such as Phytophthora cinnamomi and Phytophthora plurivora. Epoformin is suitable for research applications focusing on antimicrobial mechanisms and the study of plant-pathogen interactions.
