Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Actinobolin is an antibiotic that primarily inhibits protein synthesis by targeting both bacterial and eukaryotic ribosomes. Demonstrating effective antibacterial activity, Actinobolin exhibits IC50 values of 19.2 μmol/L against Mycobacterium smegmatis, 27.9 μmol/L against Escherichia coli, and 288 μmol/L against rabbit reticulocyte lysate (RRL). This compound is valuable for research applications focused on protein synthesis inhibition and antimicrobial activity studies. -
Antibiotic
Chrymutasin B is a glycosidic antibiotic with potent cytotoxic properties. Its primary mechanism involves inhibiting cellular proliferation, making it a valuable tool for antitumor research. Chrymutasin B is utilized in studies focused on cancer therapeutics and the exploration of antibiotic efficacy against cancer cell lines. -
Antitumor Antibiotic
Minimycin, also known as Oxazinomycin, is an antitumor antibiotic targeting a variety of cancer cell lines. It exhibits broad-spectrum antibacterial activity and has demonstrated significant inhibitory effects against mouse Ehrlich ascites carcinoma, as well as both ascitic and solid forms of sarcoma-180. This compound is particularly valuable for research in oncology and antimicrobial studies. -
Nucleoside Antibiotic
2'-Amino-2'-deoxyadenosine is a nucleoside antibiotic known for its ability to inhibit various strains of Mycoplasma. By targeting the synthesis pathways within these microorganisms, it demonstrates significant antibacterial activity. This compound is widely employed in research applications focused on studying bacterial infections and developing novel therapeutic strategies against Mycoplasma-related diseases. -
Antibiotic
Noboritomycins B is a polyether antibiotic that exerts potent activity against Gram-positive bacteria. It demonstrates effectiveness in inhibiting bacterial growth, making it valuable for studies focused on bacterial infections. Additionally, Noboritomycins B exhibits a weak anti-coccidial effect, providing insights into its potential applications in parasitic research. -
Antibiotic
Pneumocandin A2 is a lipopeptide antibiotic that primarily targets the synthesis of 1,3-β-glucan, an essential component of fungal cell walls. This compound exhibits potent anti-Candida activity with an IC50 value ranging from 0.07 to 0.5 µg/mL in vitro, making it a valuable tool for studying fungal infections. Pneumocandin A2 is utilized in research focused on antifungal mechanisms and the development of therapeutic interventions against Candida species. -
Antibiotic
Everninomicin D is a potent antibiotic targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable tool for research involving bacterial infections and the study of antibiotic resistance mechanisms. Its unique mechanism of action allows for exploration in the development of new antimicrobial therapies. -
Antibiotic
Neomycin F is an aminoglycoside antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as mycobacteria and certain protozoa. Neomycin F is particularly effective in treating infections such as amebic dysentery and select cases of bacillary dysentery, making it a valuable reagent in microbiological research and pharmaceutical applications. -
Antibiotic
N(5)-Hydroxy-L-arginine is an antibiotic that exerts its activity against both Gram-positive and Gram-negative bacteria. This compound is valuable for research focused on bacterial inhibition and exploring mechanisms of antibiotic resistance. Its unique structure and function make it an essential reagent for investigating antibacterial therapeutic strategies. -
Antibacterial Agent
16-Deethylindanomycin is an antibiotic derived from Streptomyces setonii, targeting bacterial cell function. It demonstrates potent antimicrobial activity against gram-positive bacteria, including Staphylococcus spp. and Streptococcus, with a minimum inhibitory concentration (MIC) of 2-4 µg/mL. Additionally, 16-Deethylindanomycin exhibits anticoccidial properties against Eimeria tenella, making it valuable for research in infectious diseases and veterinary applications. -
Antibiotic
DC-86-M is an antibiotic derived from the bacterium Streptomyces luteogriseus, known for its potent antibacterial properties. It demonstrates antibacterial activity against various strains, including Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL. Additionally, DC-86-M has shown antitumor effects against mouse sarcoma 180, exhibiting a lethal dose (LD50) of 25 mg/kg. This reagent can be utilized in studies involving antibiotic efficacy and cancer research. -
Antibiotic
Monamycin G1 is an ester peptide antibiotic that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable tool for microbiological research. This compound can be utilized in studies involving bacterial resistance mechanisms and the development of new therapeutic agents against Gram-positive infections. -
Insecticidal Antibiotic
Sesquicillin A is an insecticidal antibiotic that serves as a fungal metabolite derived from white plantain. It is effective in inhibiting the growth of Artemia salina brine shrimp, demonstrating a minimal inhibitory concentration (MIC) of 6.25 µg/mL. This compound is valuable for research applications focused on entomology and the development of biopesticides. -
Antibiotic
Pluracidomycin D is a carbapenem antibiotic that targets a broad range of bacterial pathogens. It exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool in microbiological research and antibiotic development. Its unique mechanism of action contributes to its effectiveness in combating bacterial resistance, paving the way for potential therapeutic applications. -
Antibiotic
Gentamicin A is an antibiotic that targets a broad spectrum of Gram-positive and Gram-negative bacteria. It exhibits significant antibacterial activity, particularly against methicillin-sensitive Staphylococcus species. This compound is widely utilized in microbiological research to study bacterial resistance mechanisms and to evaluate antibiotic efficacy in clinical and laboratory settings. -
Antibiotic
Pyrrocidine A is an antibiotic that exhibits notable antibacterial activity, derived from LL-Cyan426. This compound targets various bacterial strains, making it a valuable reagent for research focused on bacterial infections and antibiotic development. Its unique mechanism of action offers potential insights into novel therapeutic strategies against antibiotic-resistant pathogens. -
Antibiotic
Monamycin D1 is an ester peptide antibiotic that targets Gram-positive bacteria. This compound exhibits potent antibacterial activity, making it a valuable tool for research applications focused on bacterial pathogenesis and antibiotic resistance. Its efficacy in inhibiting Gram-positive strains provides insights into antibiotic mechanisms and potential therapeutic strategies. -
Antitumor Antibiotic
Cervicarcin is an antitumor antibiotic that predominantly targets cancerous cells through its potent inhibitory action. It exhibits significant cytotoxicity against sarcoma 180 and sarcoma NF, while demonstrating a lesser impact on sarcoma 37, Ehrman's ascites cancer, and Friend leukemia. This compound is valuable for research applications focused on investigating tumor biology and evaluating therapeutic strategies for various sarcomas. -
Antibacterial Agent
Antibacterial Agent 287, a derivative of Deoxynybomycin, functions primarily as an antibacterial agent. It demonstrates potent antibacterial activity against various Gram-negative bacteria, exhibiting minimum inhibitory concentrations (MICs) of 0.5 μg/mL for wild-type Staphylococcus aureus, 0.5 μg/mL for wild-type Escherichia coli, and 0.06 μg/mL for E. coli ΔtolC. This compound is particularly relevant for research into multidrug-resistant (MDR) bacterial infections. -
Antitumor Antibiotic
Memnobotrin A is an antitumor antibiotic derived from Memnoniella echinata (JS6308). This compound exhibits significant inhibitory effects on various cancer cell lines, including NCI-460, MCF7, and SF-268. It serves as a valuable tool for research applications focused on elucidating mechanisms of cancer cell growth and resistance. -
Antibiotic
Pluracidomycin C3 is a carbapenem antibiotic that exhibits potent activity against both Gram-positive and Gram-negative bacteria. This compound disrupts bacterial cell wall synthesis, making it a valuable tool in the study of antibiotic resistance mechanisms. Its efficacy in various bacterial models supports its use in researching novel antimicrobial therapies and evaluating susceptibility patterns in pathogenic strains. -
Antibiotic
2-Hydroxygentamicin B is a 3 aminoglycoside antibiotic that exerts its action by inhibiting bacterial protein synthesis. It demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is used in microbiological research to explore mechanisms of antibiotic resistance and the efficacy of various treatment regimens. -
Aminoglycoside Antibiotic
Tobramycin (monosulfate) is a broad-spectrum aminoglycoside antibiotic primarily targeting bacterial ribosomes to inhibit protein synthesis. It exhibits potent antibacterial activity against a range of gram-negative bacteria, particularly Pseudomonas aeruginosa, making it valuable in the treatment of moderate to severe infections. Tobramycin monosulfate is commonly utilized in research to investigate pneumonia and other infections caused by susceptible organisms. -
Antibiotic
Asparenomycin A is a carbapenem antibiotic that effectively inhibits β-lactamase enzymes. This compound demonstrates potent antibacterial activity, making it valuable for research into antibiotic resistance and the development of novel therapeutic strategies. Its mechanism of action and strong efficacy against resistant bacterial strains support its application in microbiological studies and drug development initiatives. -
Antibiotic
Nanaomycin D is an antibiotic that targets bacterial cell processes to exert its antibacterial activity. It effectively inhibits the growth of various bacterial strains, making it a valuable tool for microbiological studies. Researchers can use Nanaomycin D to investigate bacterial resistance mechanisms and the efficacy of antimicrobial agents in treating bacterial infections. -
Antibiotic
Coumamidine γ1 is a potent alkaline sugar antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity, including significant efficacy against Pseudomonas aeruginosa. This compound is valuable for research applications focused on combating antibiotic-resistant pathogens and studying bacterial resistance mechanisms. -
Antibiotic
8-Hydroxyerythromycin A is a semi-synthetic antibiotic primarily targeting bacterial infections. This compound exhibits significant antibacterial activity, making it valuable in the study of mechanisms of antibiotic resistance and in the development of new therapeutic strategies. It is applicable in various research fields, including microbiology and pharmacology, where understanding antibiotic efficacy is essential. -
Antibiotic
Ibafloxacine is a fluoroquinolone antibiotic designed primarily for veterinary applications. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, leading to the disruption of DNA replication and transcription in susceptible organisms. Its key biological activity includes effective treatment against various bacterial infections in animals, making it a valuable tool for veterinary medicine research and development. -
β-lactamase Antibiotic
Tigemonam is a monobactam antibiotic that targets β-lactamase enzymes, demonstrating a Ki of 0.86 μM against Enterobacter cloacae P99 and 50.8 μM against Escherichia coli TEM-1. It binds to penicillin-binding proteins 1a, 3, and 4, effectively inhibiting bacterial cell wall synthesis and exhibiting bactericidal activity against a range of aerobic gram-negative bacteria, including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam is resistant to hydrolysis by multiple β-lactamases and has been shown to reduce bacterial load in systemic and localized infections in rodent models. This compound is valuable for research into gram-negative bacterial infections, particularly acute pyelonephritis, lung infections, and thigh muscle infections. -
Antibiotic
Tauroxicum is an antibiotic substitute that functions as a non-toxic, non-antimicrobial agent. It has been shown to enhance the health, productivity, feed efficiency, and weight gain of livestock animals. This reagent serves as a valuable tool in animal husbandry, offering a means to support livestock welfare while potentially reducing reliance on traditional antibiotics. -
Antibacterial Agent
Lysozyme from chicken egg white is an antibacterial enzyme that primarily targets and lyses gram-positive bacteria. Its bactericidal activity makes it useful in various research applications, including studies on HIV infection and the mechanisms underlying pulmonary emphysema. This enzyme plays a significant role in investigating bacterial pathogenesis and serves as a model for understanding immune responses. -
β-lactamase Inhibitor
Taniborbactam hydrochloride is a reversible and selective β-lactamase inhibitor that targets various β-lactamase enzymes, demonstrating IC50 values ranging from 8 to 530 nM, with specific IC50s of 30 nM for KPC-2, 32 nM for AmpC, 42 nM for OXA-48, and 20 nM for VIM-2. This compound is effective against Gram-negative bacteria, making it a valuable tool in the study of antibiotic resistance mechanisms and the development of novel antibacterial strategies. Researchers can utilize Taniborbactam hydrochloride in investigations aimed at enhancing the efficacy of β-lactam antibiotics. -
Bacterial Inhibitor
(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERα and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer. -
Antibacterial agent
S-Methyl thiomethanesulfonate (MMTS) is a sulfur-containing compound recognized for its antibacterial properties. It exerts its biological activity through the inhibition of microbial growth, making it valuable for studies focused on bacterial infections and plant-pathogen interactions. MMTS serves as a key reagent in research involving antimicrobial screening and the development of new antibacterial agents. -
LAL Inhibitor
Lalistat 1 is a selective and competitive inhibitor of lysosomal acid lipase (LAL), demonstrating an IC50 of 68 nM against purified human LAL. It also inhibits immunoglobulin A1 protease (IgA1P) from Haemophilus influenzae while exhibiting minimal effects on other serine hydrolases such as trypsin and β-lactamase. This compound is valuable for investigating Niemann-Pick type C (NPC) disease and related metabolic disorders. -
Beta-lactamase Inhibitor
Xeruborbactam disodium is a potent beta-lactamase inhibitor that targets both serine and metallo beta-lactamases with exceptional efficacy. This ultra-broad-spectrum compound operates at nanomolar concentrations, rendering it a valuable tool in combating antibiotic resistance. It is suitable for research applications aimed at understanding beta-lactamase mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Isoforsythiaside is a phenylethanoid glycoside known for its antioxidant and antibacterial properties. It exhibits minimum inhibitory concentrations (MICs) of 40.83 μg/mL against Escherichia coli and Pseudomonas aeruginosa, and 81.66 μg/mL against Staphylococcus aureus. This compound is useful in research applications focusing on antibacterial agents and may offer insights into microbial resistance mechanisms. -
Antibacterial Agent
Adamantane-carboxylic acid is an antibacterial agent that demonstrates inhibitory activity against various microorganisms, including both Gram-positive and select Gram-negative bacteria. This compound operates by altering the permeability of the bacterial cell membrane and can form a 1-monoacylglycerol derivative through a direct reaction with glycidol. It serves as a valuable reagent in research aimed at developing antibacterial agents, particularly in the food and cosmetic industries, to mitigate harmful microbial flora and enhance product shelf life. -
Bacterial Inhibitor
Roseoflavin is a bacterial inhibitor, functioning as an antimetabolite analog of riboflavin and flavin mononucleotide. This natural pigment, originally extracted from Streptomyces davawensis, exhibits potent antimicrobial properties. It is commonly utilized in research applications aimed at studying bacterial metabolism and the mechanisms of antibiotic resistance. -
Antibacterial Agent
D-Cysteine is the D-isomer of cysteine, known for its antibacterial properties. It exhibits inhibitory activity against key pathogens such as Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. Additionally, D-Cysteine plays a regulatory role in the proliferation of neural progenitor cells, making it valuable in various research applications focused on antibacterial mechanisms and neurobiology. The no-observed-adverse-effect level in rat studies is reported to be less than 500 mg/kg/day. -
Bacterial Inhibitor
Poly-L-lysine hydrochloride is a cationic polymer that functions as a bacterial inhibitor by enhancing cell adhesion through electrostatic interactions with negatively charged cell membranes. It promotes liquid-liquid phase separation (LLPS) at low concentrations while inhibiting LLPS at elevated concentrations, making it a versatile tool for cell culture applications. This reagent is particularly useful in studies involving bacterial attachment mechanisms and cell substrate interactions. -
Antibacterial Agent
Ceftaroline is an N-phosphono-type cephalosporin with potent antibacterial properties. It exhibits activity against a broad spectrum of gram-positive and gram-negative bacteria, making it a valuable agent for research in microbial susceptibility and resistance. Ceftaroline is primarily utilized in studies aimed at developing new therapeutic strategies to combat bacterial infections. -
Bacterial Riboflavin Riboswitches Inhibitor
Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches, targeting their regulatory mechanism to disrupt riboflavin biosynthesis. This compound exhibits a high degree of selectivity and is valuable for studying riboswitch function and its role in bacterial gene regulation. Ribocil-C is applicable in research focusing on microbial metabolism and the development of antibacterial strategies. -
Antibacterial Agent
Temocillin disodium is a 6-α-methoxy penicillin that functions as an antibacterial agent. It exhibits activity against a range of gram-negative bacteria, making it valuable in research focused on infectious diseases and antibiotic resistance. Temocillin disodium can be utilized in studies involving microbial susceptibility and therapeutic interventions for bacterial infections. -
Bacterial Collagenase Substrate
FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that acts as a substrate specifically for bacterial collagenase and spirochete metalloendopeptidase. It is selectively hydrolyzed at the Leu-Gly bond by spirochete collagenase, making it useful for studying peptide bond hydrolysis kinetics. This reagent can also be employed in detecting collagenase-mediated cleavage reactions using turbidimetry through absorbance reduction, providing valuable insights into enzyme activity and specificity. -
Antibacterial agent
2-Hydroxycinnamic acid functions primarily as an antibacterial agent, exhibiting potent antimicrobial properties. This phenolic acid demonstrates efficacy against Staphylococcus aureus and remains unaffected by common drug resistance mechanisms. Additionally, it has shown inhibitory effects on HIV/SARS-CoV S pseudovirus, with an IC50 of 0.3 mM. Furthermore, 2-Hydroxycinnamic acid also possesses neuroprotective and antitumor activities, making it valuable for a variety of research applications in microbiology and oncology. -
Antibacterial Agent
MRL-494 hydrochloride is an antibacterial agent that functions as an inhibitor of the β-barrel assembly machine A (BamA), effectively circumventing efflux and the outer membrane permeability barrier. It exhibits significant antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) of 12.5 μM for Staphylococcus aureus COL, and against Gram-negative bacteria, with an MIC of 25 μM for Escherichia coli JCM158. This compound is suitable for research applications focused on combating bacterial infections and studying membrane protein assembly. -
Antibacterial Agents
Polyaniline is a conductive polymer primarily known for its ability to act as an antibacterial agent. Its unique electrical properties and structure enhance its interaction with microbial cells, leading to effective inhibition of growth. This compound is particularly useful in the development of antimicrobial coatings and materials for biomedical applications, making it an important resource for research in infection control and materials science. -
Antibacterial Agent
4aα,7α,7aα-Nepetalactone is an antibacterial agent that demonstrates activity against a range of pathogenic bacteria. It effectively inhibits the growth of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, and Enterococcus faecalis. This compound is valuable for research applications focused on the study of antibacterial mechanisms and the development of new antimicrobial therapies. -
Bacterial Inhibitor
Lymecycline is a tetracycline derivative known for its mechanism as a bacterial inhibitor. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of bacterial infections. Additionally, Lymecycline possesses anti-inflammatory properties, which may be beneficial in treating conditions where inflammation plays a significant role. Its applications in research include studying bacterial resistance mechanisms and exploring its therapeutic potential in inflammatory diseases.
