Other inhibitors

Bisoctrizole is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. Also a hybrid UV absorber, reflecting and scattering UV.

BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.

(Z)-2-decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a disp .

9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.

Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1), an antioxidant dietary supplement.

BMX-IN-1 is a highly selective and potent irreversible inhibitor which target the cysteine residue in the BMX ATP binding domain.

Cot inhibitor-2 is a COT/Tpl2 inhibitor.

Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator; its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.

EBE-A22 is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.

Etimizol was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).

MB05032 is a special and efficacious GNG inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.

N3PT is a potent and selective transketolase(TK) inhibitor (IC50= 22 nM for Apo-TK) both in vitro and in vivo.

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.

Pafuramidine is an orally bioavailable prodrug of furamidine, which has clinical activity against Pneumocystis pneumonia.

Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms.

Retinyl glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.

sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types.

Sodium formononetin-3'-sulfonate is a water-sol. derivate of formononetin.

R18, antagonist of 14.3.3 proteins (KD ??? 80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation.

Plumbagin, exhibits cytotoxicity in rodent models of carcinogenesis and carcinoma; has antifungal, antiviral, and antibacterial action.

Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides.

N/A

K-7174 is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1beta or TNF-alpha.

K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1beta or TNF-alpha.

KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma.

Finafloxacin hydrochloride is a fluoroquinolone compound.

AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM,

N/A

Bucetin is an analgesic and antipyretice agent with a risk of carcinogenesis.

Formononetin (Formononetol) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone. It is used as a blood enhancer and to improve blood microcirculation in complementary and alternative medicine. It promotes endothelial repair and wound healing in a process involving the over-expression of Egr-1 transcription factor through the regulation of the ERK1/2 and p38 MAPK pathways.

Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.

Fumalic acid(Ferulic acid) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. It has many pharmacology functions, such as anti-blood platelet collection , ease pain better the alive of prostate , relax the blood vessel convulsion.

Gadodiamide is a gadolinium-based MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.

Gastrodin (Gastrodine) is a polyphenol. It is the glucoside of 4-hydroxybenzyl alcohol (gastrodigenin).

Gentamycin(Gentacycol) is an aminoglycoside antibiotic and was isolated from Micromonospora species

Gestodene is a progestogen hormonal contraceptive.

L-Glutamine is one of the 20 amino acids encoded by the standard genetic code.

Guaifenesin(Guaiphenesin) is thought to act as an expectorant.

Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum. The increase of SGOT, SGPT activities in CCl4 liver injury were significantly reduced by treatment with Gypenoside. It also elevated the A/G ratio.

Hesperidin is a flavanone glycoside found abundantly in citrus fruits.

Hydrochlorothiazide is a first line diuretic compound of the thiazide class.

Hydroxyurea (Cytodrox) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.

Hyodeoxycholic (HDCA) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.

Iloperidone is an atypical antipsychotic for the treatment of schizophrenia.

Indapamide(Lozol) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

Indole-3-carbinol is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables.

L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar. It can be classified as either a methyl-pentose or a 6-deoxy-hexose.

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.

Calcium Folinate, Pentahydrate supplies cells with tetrahydrofolate and diminishes methotrexate toxicity without abolishing antitumor effect.

Loteprednol Etabonate is an ophthalmic corticosteroid. It is used as an anti-inflammatory.