TRi-1

Catalog No.: A18556

TXNRD1 inhibitor

TRi-1

TRi-1 Chemical Structure

CAS NO. 246020-68-8

TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$260.00
50 mg
$580.00
100 mg
$880.00
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Biological Activity

TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.42 mL 152.1 mL 304.2 mL
0.5 mM 6.08 mL 30.42 mL 60.84 mL
1 mM 3.04 mL 15.21 mL 30.42 mL
5 mM 0.61 mL 3.04 mL 6.08 mL

*The above data is based on the productmolecular weight 328.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18556
Actions Inhibitor
M. Wt 328.73
Formula C12H9ClN2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 246020-68-8
Synonyms TRi1
SMILES O=[N+](C1=CC=C(OC)N=C1S(=O)(C2=CC=C(Cl)C=C2)=O)[O-]

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