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$0.00 Biological Activity
TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.42 mL | 152.1 mL | 304.2 mL |
| 0.5 mM | 6.08 mL | 30.42 mL | 60.84 mL |
| 1 mM | 3.04 mL | 15.21 mL | 30.42 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.08 mL |
*The above data is based on the productmolecular weight 328.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18556 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 328.73 |
| Formula | C12H9ClN2O5S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 246020-68-8 |
| Synonyms | TRi1 |
| SMILES | O=[N+](C1=CC=C(OC)N=C1S(=O)(C2=CC=C(Cl)C=C2)=O)[O-] |
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