SPL-410

Catalog No.: A18563

hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor

SPL-410

SPL-410 Chemical Structure

CAS NO. 2351886-00-3

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM.

Availability: Out of stock

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5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.98 mL 99.89 mL 199.77 mL
0.5 mM 4 mL 19.98 mL 39.95 mL
1 mM 2 mL 9.99 mL 19.98 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 500.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18563
Actions Inhibitor
CAS No. 2351886-00-3
Formula C24H31F3N2O4S
M. Wt 500.57
Solubility DMSO
Purity >98%
Synonyms SPL410, SPL 410
SMILES N[[email protected]]([[email protected]@H](O)CN(C1CCC1)S(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C3=CC=C(OC(F)(F)F)C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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