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Biological Activity
SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.98 mL | 99.89 mL | 199.77 mL |
| 0.5 mM | 4 mL | 19.98 mL | 39.95 mL |
| 1 mM | 2 mL | 9.99 mL | 19.98 mL |
| 5 mM | 0.4 mL | 2 mL | 4 mL |
*The above data is based on the productmolecular weight 500.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18563 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2351886-00-3 |
| Formula | C24H31F3N2O4S |
| M. Wt | 500.57 |
| Purity | >98% |
| Synonyms | SPL410, SPL 410 |
| SMILES | N[C@H]([C@@H](O)CN(C1CCC1)S(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C3=CC=C(OC(F)(F)F)C=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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