Calcium Channels



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Catalog No. Product Name Application Product Information
A11314

AMG 073 (Cinacalcet)

calcimimetic compound
AMG-073 (Cinacalcet) represents a new class of compounds for the treatment of hyperparathyroidism.
A10219 SALE

AMG-073 HCl (Cinacalcet HCl)

CaSR activator
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium.
A10068 SALE

Amlodipine

L-type calcium channel blocker
Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
A10069

Amlodipine besylate (Norvasc)

L-type calcium channel blocker
Amlodipine-besylate is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
A11405

Astragaloside A

Ca2+ signaling modulator
Astragaloside A is a novel regulator of HIF-1α and angiogenesis through the PI3K/Akt pathway in HUVECs that are exposed to hypoxia.
A11219

Azelnidipine

calcium channel blocker
Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence. that attenuates liver fibrosis and may increase antioxidant defence.
A13989 SALE

BAPTA tetrapotassium

Selective calcium chelator
BAPTA tetrapotassium is a selective calcium chelator with greater affinity for Ca2+ than Mg2+.
A14023 SALE

BAPTA/AM

Selective calcium chelator
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
A11730

Benidipine hydrochloride

-
Benidipine hydrochloride is a long-acting T-type calcium channel blocker, on blood pressure and renal function in hypertensive patients with diabetes mellitus.
A10215 SALE

Cilnidipine

Calcium channel blocker
Cilnidipine is a dual blocker of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals that supply.
A11206 SALE

CK-1827452 (Omecamtiv mecarbil)

Myosin activator
CK-1827452 is a selective cardiac specific myosin activator.
A11746 SALE

Clevidipine

Calcium channel blocker
Clevidipine is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is not feasible or not desirable.
A10309

Diethylstilbestrol

-
Diethylstilbestrol is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor.
A10311 SALE

Diltiazem HCl

-
Diltiazem is a nondihydropyridine (non-DHP) member of the class of drugs known as calcium channel blockers, used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.
A10487 SALE

Isradipine

calcium channel blocker
Isradipine is a calcium channel blocker of the dihydropyridine class.
A11729

Lacidipine

-
Lacidipine is a calcium channel blocker
A10553

Manidipine (Manyper)

-
Manidipine is a dihydropyridine compound and calcium channel protein inhibitor and antagonist.
A10554 SALE

Manidipine 2HCl

-
Manidipine 2HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
A10643 SALE

Nifedipine

L-type calcium channel blocker.
Nifedipine is a L-type calcium channel blocker.
A11731

Nilvadipine (ARC029)

calcium channel blocker
Nilvadipine is a calcium channel blocker (CCB) used for the treatment of hypertension and chronic major cerebral artery occlusion
A10645 SALE

Nimodipine

Calcium Channel inhibitor
Nimodipine is a L-type Ca2+ channel blocker.
A11140

NPS-2143 (SB-262470)

CaR antagonist
NPS-2143 is a selective Ca2+-sensing receptor antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM.
A12684

Pinaverium Bromide

-
Pinaverium Bromide is a spasmolytic agent with low incidence of anticholinergic effects. Pinaverium Bromide is also an antispasmodic.
A10921

Tetrandrine (Fanchinine)

Calcium Channel inhibitor
Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.

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