Catalog No.: A16346

CRAC channel inhibitor


YM-58483 Chemical Structure

CAS NO. 223499-30-7

YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.

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Biological Activity

YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.
In vitro (25°C) DMSO 76 mg/mL (180.38 mM)
Water Insoluble
Ethanol 76 mg/mL (180.38 mM)
In vivo 1% CMC Na 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.73 mL 118.67 mL 237.35 mL
0.5 mM 4.75 mL 23.73 mL 47.47 mL
1 mM 2.37 mL 11.87 mL 23.73 mL
5 mM 0.47 mL 2.37 mL 4.75 mL

*The above data is based on the productmolecular weight 421.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16346
Actions Inhibitor
CAS No. 223499-30-7
Formula C15H9F6N5OS
M. Wt 421.32
Purity >98%
Synonyms YM58483, YM 58483, BPT2

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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