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Biological Activity
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.21 mL | 141.06 mL | 282.13 mL |
| 0.5 mM | 5.64 mL | 28.21 mL | 56.43 mL |
| 1 mM | 2.82 mL | 14.11 mL | 28.21 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
*The above data is based on the productmolecular weight 354.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12186 |
|---|---|
| Actions | Inhibitor, Agonist |
| CAS No. | 1402821-24-2 |
| Formula | C19H26N6O |
| M. Wt | 354.45 |
| Purity | >98% |
| SMILES | CC[C@@H](NC1=NC(NCC2=CC=CC=C2)=C3C(N(CCC)C=N3)=N1)CO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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