GPCR/G Protein

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  1. Adenosine Analog

    2'-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has potential applications in inhibiting cancer progression. Its mechanism of action makes it a valuable tool for researchers studying cardiovascular function and cancer therapeutics.
  2. Adenosine Analog

    5′-O-[(4-Cyanophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory properties and demonstrates potential in inhibiting cancer cell proliferation. It is a valuable tool in research exploring the effects of adenosine signaling in cardiovascular diseases and cancer therapy.
  3. Adenosine Analog

    N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog that acts primarily as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for various biological research applications. Its distinctive structural properties facilitate the study of adenosine receptor interactions and signaling pathways, contributing to the understanding of cardiovascular physiology and tumor biology.
  4. Adenosine Analog

    N6-Benzyl-2’-C-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects in smooth muscle and demonstrates potential in inhibiting cancer progression. It serves as a valuable tool in studies focusing on cardiovascular function and cancer biology, facilitating research into therapeutic strategies for related conditions.
  5. Adenosine Analog

    N-[(3-Methoxyphenyl)methyl]adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant biological activity as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It is a valuable tool for researchers investigating vascular biology and cancer therapeutics.
  6. Uridine Analog

    5-Iodo-2’-β-C-methyl uridine is a uridine analog that primarily targets adenosine receptors. This compound exhibits potential antiepileptic properties and serves as a valuable tool in the investigation of anticonvulsant and anxiolytic activities. Additionally, it may contribute to the development of innovative antihypertensive agents in chemical research.
  7. Adenosine Analog

    5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine is an adenosine analog that primarily targets adenosine receptors. This compound demonstrates biological activities such as smooth muscle vasodilation and potential inhibition of cancer progression. It is valuable for research in cardiovascular studies and cancer biology, facilitating investigations into adenosine signaling and therapeutic applications.
  8. Adenosine Analog

    N6-Methyl-xylo-adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. Its unique properties make it a valuable tool for researchers investigating vascular biology and cancer therapies.
  9. 5'-AMP Analogue

    2-Cl-5'-AMP is a 5'-AMP analogue that functions primarily by interacting with adenosine receptors. This compound exhibits key biological activity in receptor mapping research, facilitating the study of adenosine receptor signaling pathways and their physiological roles. Its use in biochemical assays enables a deeper understanding of receptor-ligand interactions and their implications in various biological systems.
  10. Adenosine Analog

    N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant vasodilatory effects by relaxing smooth muscle and has demonstrated potential in inhibiting cancer progression. This compound is valuable in biomedical research, particularly in studies focused on cardiovascular health and cancer therapy.
  11. Adenosine Analog

    9-(β-D-Xylofuranosyl)adenine is an adenosine analog that primarily acts as a vasodilator by targeting adenosine receptors. This compound has demonstrated significant biological activity, including the inhibition of cancer progression. It is particularly useful for researchers exploring the mechanisms of vasodilation and the therapeutic potential of adenosine-related pathways in cancer biology.
  12. Adenosine Analog

    2'-O-Methyladenosine 5'-monophosphate triethylammonium is an adenosine analog that primarily targets adenosine receptors. It exhibits significant biological activity, functioning as a smooth muscle vasodilator while also demonstrating potential for inhibiting cancer progression. This compound is valuable for research applications focusing on cardiovascular studies and cancer biology.
  13. Adenosine Analog

    8-Chloro-2'-deoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant biological activity as a potential vasodilator and has demonstrated inhibitory effects on cancer progression. It is useful in various research applications, particularly in studying the pharmacological effects of adenosine and its derivatives in cardiovascular and oncology research.
  14. Adenosine Analog

    2-Methoxy-2'-deoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression, making it relevant for various research applications, including cardiovascular studies and oncology. Its structural similarity to adenosine allows for exploration in drug development targeting related pathways.
  15. Adenosine Analog

    N-(2-Phenoxyacetyl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool in cancer research and studies related to vascular biology.
  16. Adenosine Analog

    N6-Benzoyl-9-β-D-arabinofuranosyladenine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and demonstrates potential in inhibiting cancer progression. It serves as a valuable tool in studies focused on cardiovascular research and oncology, enabling researchers to explore the therapeutic implications of adenosine signaling pathways.
  17. Adenosine Analog

    8-Allylthioadenosine is an adenosine analog that primarily targets adenosine receptors. It demonstrates smooth muscle vasodilatory effects and has been implicated in inhibiting cancer progression, making it a valuable compound for oncology research. Its utility extends to studies involving vascular biology and the modulation of cellular signaling pathways.
  18. Adenosine Analog

    3’-O-(2-Methoxyethyl)-2-aminoadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory properties and has demonstrated potential in inhibiting cancer progression. Research applications include studying vascular biology, exploring therapeutic avenues in oncology, and investigating the signaling pathways mediated by adenosine receptors.
  19. Adenosine Analog

    3',5'-TIPS-N-Ac-Adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has potential applications in inhibiting cancer progression. It is valuable for research related to vascular biology and oncology, facilitating the study of adenosine receptor signaling pathways and their therapeutic implications.
  20. Adenosine Analog

    8-(Methylamino)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant vasodilatory effects on smooth muscle and has been demonstrated to possess anti-cancer properties by inhibiting tumor progression. It is utilized in various research applications related to vascular biology and oncology.
  21. Adenosine Analog

    N6-(3-Trifluoromethylbenzyl)-2’-C-methyl adenosine is an adenosine analog that primarily acts on adenosine receptors. This compound demonstrates smooth muscle vasodilatory properties and has potential applications in inhibiting cancer progression. Its structural modifications enhance its affinity and selectivity, making it a valuable reagent for research in vascular biology and oncology.
  22. Adenosine Analog

    N6,N6-Dimethyl-xylo-adenosine is an adenosine analog with a primary mechanism of action involving modulation of adenosine receptors. This compound has demonstrated significant smooth muscle vasodilator activity and holds potential in inhibiting cancer progression. It is widely utilized in research applications focusing on vascular biology and oncology.
  23. Adenosine Analog

    3'-β-C-Methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activity as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It is useful in research applications focused on cardiovascular function and cancer biology.
  24. Adenosine Analog

    9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine is an adenosine analog that primarily acts on adenosine receptors. This compound exhibits smooth muscle vasodilatory activity and has demonstrated potential in inhibiting the progression of various cancers. It serves as a valuable tool in biochemical research focusing on vascular biology and oncology.
  25. Adenosine Analog

    2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine is an adenosine analogue targeting adenosine receptors. It exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. This compound is valuable for research applications focusing on vascular biology and cancer therapeutics.
  26. Adenosine Analog

    2′-β-C-Methyl-2-methoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. Its applications extend to research involving cardiovascular function and cancer biology, making it a valuable tool for exploring therapeutic strategies in these areas.
  27. Adenosine Analog

    N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. This compound is valuable in research focused on vascular biology and cancer therapeutics, offering insights into adenosine receptor signaling pathways and their clinical implications.
  28. Adenosine Analog

    2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activities such as promoting smooth muscle vasodilation and potentially inhibiting cancer progression. It is a valuable reagent for researchers investigating vascular biology, cancer therapeutics, and adenosine signaling pathways.
  29. Adenosine Analog

    2-Amino-N-(3-methyl-2-buten-1-yl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has been implicated in the inhibition of cancer progression. It serves as a valuable tool for research in vascular biology and cancer therapeutics, facilitating the exploration of adenosine receptor signaling pathways and their implications in various disease states.
  30. Adenosine Analog

    5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine is an adenosine analog that serves as a key modulator of adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has potential applications in cancer research due to its ability to inhibit tumor progression. It is particularly useful for studies investigating the roles of adenosine in vascular biology and oncology.
  31. Adenosine Analog

    2-Amino-N6,N6-dimethyl-2’-O-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has potential applications in inhibiting cancer progression. It is valuable for research in cardiovascular studies and oncology, providing insights into the therapeutic potential of adenosine-related pathways.
  32. Adenosine Analog

    3’-beta-C-Methyl-N6-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. Its unique structure allows for various research applications, particularly in studies focusing on cardiovascular function and tumor biology.
  33. Adenosine Analog

    8-Allyloxyadenosine is an adenosine analog primarily targeting adenosine receptors. This compound exhibits significant biological activity as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool in research applications focused on cardiovascular health and cancer therapy.
  34. Adenosine Analog

    2-(4-Cyanobenzyl)thioadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits potent vasodilatory effects on smooth muscle, making it of interest in cardiovascular research. Additionally, it has demonstrated potential in inhibiting cancer progression, making it a valuable tool for cancer biology studies.
  35. Adenosine Analog

    4’-C-Methyl-N6-methyladenosine is an adenosine analogue that primarily targets adenosine receptors. This compound exhibits significant biological activity as a vasodilator, promoting smooth muscle relaxation, and has shown potential in inhibiting cancer cell progression. It serves as a valuable tool in research applications focused on vascular biology and cancer therapeutics.
  36. Adenosine Analog

    N6-Isopentenyl-2’-C-methyladenosine is an adenosine analog that primarily acts as a vasodilator by influencing adenosine receptors. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure allows for diverse applications in studying nucleotide metabolism and therapeutic interventions targeting adenosine signaling pathways.
  37. Adenosine Analog

    2-(4-Methylbenzyl)thioadenosine is an adenosine analog that primarily targets adenosine receptors. It is recognized for its vasodilatory effects on smooth muscle and demonstrates potential in inhibiting cancer progression. This compound serves as a valuable tool in researching adenosine receptor signaling, cardiovascular function, and cancer biology.
  38. Adenosine Analog

    N-Propargyladenosine is an adenosine analogue that primarily acts as a vasodilator by targeting adenosine receptors. This compound exhibits significant biological activity, demonstrating potential in inhibiting cancer progression. Additionally, N-Propargyladenosine functions as a click chemistry reagent, containing an alkyne group that allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it valuable for various chemical biology applications.
  39. Adenosine Analog

    3′-O-Methyladenosine is an adenosine analogue that primarily targets adenosine receptors. This compound exhibits significant biological activity as a smooth muscle vasodilator and has also demonstrated potential in inhibiting cancer progression. Its applications extend to various research fields, including cardiovascular studies and oncology, making it a valuable tool for investigating adenosine-related pathways and therapeutic targets.
  40. Adenosine Analog

    2’,3’,5’-Tri-O-acetyl adenosine is an adenosine analog that primarily targets adenosine receptors, serving as a potent smooth muscle vasodilator. This compound has been shown to exert inhibitory effects on cancer progression, making it a valuable tool in oncology research. It is useful for studying adenosine signaling pathways and their implications in various biological processes.
  41. Adenosine Analog

    2,8-Dimethyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool for research in cardiovascular studies and cancer biology.
  42. Adenosine Analog

    2-Chloro-2′-β-C-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and demonstrates the potential to inhibit cancer progression. It serves as a valuable tool for research applications focused on vascular biology and cancer therapeutics.
  43. Platelet Aggregation Inhibitor

    U-51605 is a platelet aggregation inhibitor that targets thromboxane synthesis. It also functions as a prostaglandin I2 synthase inhibitor and has been shown to block retinal vasodilation responses induced by nitric oxide donors like NOR3. This reagent is valuable for research applications focusing on cardiovascular health and vascular biology.
  44. S1P₁ Agonist

    PPI-4955 is a selective agonist of the sphingosine-1-phosphate receptor subtype 1 (S1P₁), displaying an EC50 of 1.62 nM. Its active phosphorylated form, PPI-4955-P, demonstrates exceptional receptor selectivity, with IC50 values of 0.23 nM for hS1P₁, 2000 nM for hS1P₃, 6.5 nM for hS1P₄, and 184 nM for hS1P₅. This compound significantly enhances in vivo phosphorylation efficiency, leading to lymphocyte reduction and a potential decrease in cardiovascular risk. PPI-4955 is applicable for research in immunomodulation and cardiovascular studies.
  45. Exenatide Impurity

    (D-Asn28)-Exenatide is an impurity of Exenatide, which functions as a long-acting agonist of the glucagon-like peptide-1 receptor. This compound may be used in research applications focusing on peptide synthesis, quality control, and pharmacological studies involving GLP-1 receptor pathways. Its significance lies in understanding the properties and effects of Exenatide-related compounds.
  46. Somatostatin Receptor Antagonist

    Cyclosomatostatin is a potent somatostatin receptor antagonist that specifically targets somatostatin receptor type 1 (SSTR1). This compound effectively inhibits SSTR1 signaling, leading to reduced cell proliferation, decreased ALDH+ cell population size, and diminished sphere formation in colorectal cancer cells. It serves as a valuable tool for research applications focused on understanding the role of somatostatin signaling in cancer biology.
  47. Somatostatin Neuropeptide

    Cortistatin-17 (human) is a somatostatin neuropeptide that modulates neuroendocrine signaling through its interaction with somatostatin receptors. Its biological activities include the regulation of endocrine and exocrine functions, as well as potential anti-inflammatory effects. This peptide is valuable for research applications related to cancer, inflammation, autoimmunity, fibrosis, and pain.
  48. Somatostatin Receptor Antagonist

    BIM-23056 is a linear octapeptide that acts as a potent antagonist of somatostatin receptors sst3 and sst5, exhibiting Ki values of 10.8 nM and 5.7 nM, respectively. This compound is valuable for research into somatostatin signaling pathways and their role in various physiological and pathological conditions. Applications include studies in neuroendocrinology and potential therapeutic investigations targeting somatostatin-related disorders.
  49. Somatostatin Receptor Antagonist

    SRA880 is a selective antagonist of the somatostatin receptor subtype sst(1). This non-peptide compound has demonstrated antidepressant-like effects, particularly in conjunction with Imipramine. SRA880 can be utilized in research applications focused on mood disorders and somatostatin signaling pathways, contributing valuable insights into potential therapeutic mechanisms.
  50. Somatostatin Receptor Agonist

    Somatostatin-28 (1-14) serves as an agonist of somatostatin receptors. This N-terminal fragment of the neuropeptide somatostatin-28 plays a critical role in regulating various physiological processes, including hormone secretion and neurotransmission. It is widely used in research applications investigating metabolic regulation, neurobiology, and potential therapeutic strategies for neuroendocrine disorders.

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