NPY receptor

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  1. NPY Y2 receptor antagonist

    BIIE 0246 is a potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM).
  2. Neuropeptide FF receptor antagonist

    RF9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58??5 and 75??9 nM for hNPFF1R and hNPFF2R, respectively.
  3. NPY Y5 receptor antagonist

    GW438014A is a potent and selective neuropeptide Y Y5 receptor antagonist.
  4. neuropeptide Y Y2 receptor antagonist

    JNJ-31020028 is a novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist
  5. neuropeptide Y1 receptor antagonist

    BMS-193885 is a potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over ??1, α1, Y2, Y4 and Y5 receptors respectively.
  6. neuropeptide Y1 receptor antagonist

    Y1 receptor antagonist 1 (H 409-22 isomer) is a neuropeptide Y1 receptor antagonist.
  7. NPY5-R antagonist

    L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
  8. neuropeptide Y5 receptor antagonist

    CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
  9. NPY Y5 receptor antagonist

    Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.
  10. neuropeptide Y5 receptor antagonist

    MK-0557 is a highly selective, orally available neuropeptide Y5 receptor antagonist with a Ki of 1.6 nM.
  11. Galanin receptors GALR agonist

    Galnon is a selective, non-peptide agonist at the galanin receptors GALR.

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