NPY receptor

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  1. NPY Y2 receptor antagonist

    BIIE 0246 is a potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM).
  2. Gal3 antagonist

    HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).
  3. Neuropeptide FF receptor antagonist

    RF9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58??5 and 75??9 nM for hNPFF1R and hNPFF2R, respectively.
  4. NPY Y5 receptor antagonist

    GW438014A is a potent and selective neuropeptide Y Y5 receptor antagonist.
  5. neuropeptide Y Y2 receptor antagonist

    JNJ-31020028 is a novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist
  6. Endogenous galanin receptor agonist

    Galanin (1-30) (human) is an endogenous peptide with multiple endocrine, metabolic and behavioral effects
  7. neuropeptide Y1 receptor antagonist

    BMS-193885 is a potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over ??1, α1, Y2, Y4 and Y5 receptors respectively.
  8. neuropeptide Y1 receptor antagonist

    Y1 receptor antagonist 1 (H 409-22 isomer) is a neuropeptide Y1 receptor antagonist.
  9. NPY5-R antagonist

    L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
  10. neuropeptide Y5 receptor antagonist

    CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
  11. NPY Y5 receptor antagonist

    Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.
  12. neuropeptide Y5 receptor antagonist

    MK-0557 is a highly selective, orally available neuropeptide Y5 receptor antagonist with a Ki of 1.6 nM.
  13. GAL2 receptor PAM

    CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro.
  14. Galanin receptors GALR agonist

    Galnon is a selective, non-peptide agonist at the galanin receptors GALR.
  15. CART(55-102)(rat) is a rat satiety factor with potent appetite-suppressing activity. CART(55-102)(rat) is closely associated with leptin and neuropeptide Y. CART(55-102)(rat) can induces anxiety and stress-related behavior.
  16. neuropeptide Y (NPY) Y5 receptor agonist

    [D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats.

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