Shop By
Catalog No.
Product Name
Application
Product Information
Product Citation
-
CaSR activator
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. -
CaSR activator
AMG-073 (Cinacalcet) represents a new class of compounds for the treatment of hyperparathyroidism. -
sGC activator
YC-1 is a direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide. -
β3 adrenergic receptor activator
Mirabegron is a potent bladder relaxant and reagent for diabetes remedy.- Bhavik Patel, .et al. , Pharmacol Res Perspect, 2020, 8 (1), e00564 PMID: 32030913
-
guanylate cyclase activator
(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued. -
sGC activator?€?
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. -
FFAR1/GPR40 activator
GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. -
sGC activator
Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. -
GPR40 activator
GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. -
guanylate cyclase (GC) activator
Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets. -
Smo allosteric activator
20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. -
G proteins activator
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of signal transduction of G proteins.
