5,7,4'-Trimethoxyflavone

Catalog No.: A22408
anticancer agent
5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand. 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner.
Grouped product items
Product Name Price Stock Qty
5,?7,?4'-?Trimethoxyflavone 5mg
$107.00
In stock
5,?7,?4'-?Trimethoxyflavone 10mg
$184.00
In stock
5,?7,?4'-?Trimethoxyflavone 50mg
$547.00
In stock
5,?7,?4'-?Trimethoxyflavone 100mg
$1,071.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription 5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand. 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner.
Product Information
Catalog Num A22408
Formula C18H16O5
Molecular Weight 312.32
CAS Number 5631-70-9
SMILES COC1=C(C(C=C(C2=CC=C(OC)C=C2)O3)=O)C3=CC(OC)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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