Lapaquistat

Catalog No.: A21262

cholesterol biosynthesis inhibitor

Lapaquistat

Lapaquistat Chemical Structure

CAS NO. 189059-71-0

Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of TAK-475. Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy.

Availability: In stock

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1 mg

Regular Price: $252.00

Special Price $201.60

5 mg

Regular Price: $756.00

Special Price $604.80

10 mg

Regular Price: $1,288.00

Special Price $1,030.40

50 mg

Regular Price: $3,864.00

Special Price $3,091.20

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Biological Activity

Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of TAK-475. Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.58 mL 82.9 mL 165.81 mL
0.5 mM 3.32 mL 16.58 mL 33.16 mL
1 mM 1.66 mL 8.29 mL 16.58 mL
5 mM 0.33 mL 1.66 mL 3.32 mL

*The above data is based on the productmolecular weight 603.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21262
Actions Inhibitor
CAS No. 189059-71-0
Formula C31H39ClN2O8
M. Wt 603.1
Purity >98%
Synonyms T-91485
SMILES O=C(O)CC1CCN(C(C[[email protected]@H]2C(N(CC(C)(C)CO)C3=CC=C(Cl)C=C3[[email protected]@H](C4=CC=CC(OC)=C4OC)O2)=O)=O)CC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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