Fig. 1 · Structure
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1-Hydroxypyrene
Cat. No.
A57326
CAS
5315-79-7
Endogenous Metabolite
1-Hydroxypyrene serves as a primary endogenous metabolite and biomarker for exposure to polycyclic aromatic hydrocarbons (PAHs), particularly pyrenes. This compound is analyzed in urine samples to assess environmental and occupational exposure. Additionally, 1-Hydroxypyrene acts as an orally active agonist of the aryl hydrocarbon receptor (AhR), which is implicated in various biological processes, including renal fibrosis. Its significance in toxicological studies makes it a valuable reagent for research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 5315-79-7 |
| Applications | Endogenous Metabolite |
| Formula | C16H10O |
| Molecular Weight | 218.25 |
| SMILES | OC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.