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Acetylaszonalenin

Catalog No.: A62095
Fungal Metabolite
Acetylaszonalenin is a prenylated indole derivative that acts as a neurokinin-1 (NK1) receptor antagonist. This fungal metabolite demonstrates significant inhibition of [3H]-substance P binding to human astrocytoma cells, with a Ki value of 170 μM. Acetylaszonalenin is applicable in research exploring neurokinin signaling and its role in neuroinflammation and related neurological disorders.
Acetylaszonalenin 42230-55-7 Fungal Metabolite
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Size Price Stock Qty
500µg
$285.00
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2.5mg
$1,065.00
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAcetylaszonalenin is a prenylated indole derivative that acts as a neurokinin-1 (NK1) receptor antagonist. This fungal metabolite demonstrates significant inhibition of [3H]-substance P binding to human astrocytoma cells, with a Ki value of 170 μM. Acetylaszonalenin is applicable in research exploring neurokinin signaling and its role in neuroinflammation and related neurological disorders.
Product Information
Catalog NumA62095
FormulaC25H25N3O3
Molecular Weight415.48
CAS Number42230-55-7
SMILESO=C1N2[C@@]([H])(C(NC3=CC=CC=C13)=O)C[C@]4([C@@]2(N(C5=C4C=CC=C5)C(C)=O)[H])C(C)(C=C)C
SynonymsLL-S490β
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Metabolism > Endogenous Metabolite