8-Oxo-dATP lithium

Catalog No.: A56480
Endogenous Metabolite
8-Oxo-dATP lithium is an oxidized purine nucleoside triphosphate that targets the MTH1 enzyme. This compound plays a crucial role in cellular metabolism by being hydrolyzed into monophosphates, which effectively prevents the misincorporation of 8-oxo-dATP during DNA replication and transcription processes. It is applicable in research concerning oxidative stress, DNA damage repair mechanisms, and the fidelity of nucleotide incorporation in cellular systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
Description8-Oxo-dATP lithium is an oxidized purine nucleoside triphosphate that targets the MTH1 enzyme. This compound plays a crucial role in cellular metabolism by being hydrolyzed into monophosphates, which effectively prevents the misincorporation of 8-oxo-dATP during DNA replication and transcription processes. It is applicable in research concerning oxidative stress, DNA damage repair mechanisms, and the fidelity of nucleotide incorporation in cellular systems.
Product Information
Catalog NumA56480
FormulaC10H12Li4N5O13P3
Molecular Weight530.91
CAS Number3056945-23-1
SMILESO[C@H]1C[C@H](N(C2=NC=NC(N)=C2N3)C3=O)O[C@@H]1COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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