Fig. 1 · Structure

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8-Oxo-dATP lithium

Cat. No. A56480 CAS 3056945-23-1

Endogenous Metabolite

8-Oxo-dATP lithium is an oxidized purine nucleoside triphosphate that targets the MTH1 enzyme. This compound plays a crucial role in cellular metabolism by being hydrolyzed into monophosphates, which effectively prevents the misincorporation of 8-oxo-dATP during DNA replication and transcription processes. It is applicable in research concerning oxidative stress, DNA damage repair mechanisms, and the fidelity of nucleotide incorporation in cellular systems.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3056945-23-1
Applications Endogenous Metabolite
Formula C10H12Li4N5O13P3
Molecular Weight 530.91
SMILES
O[C@H]1C[C@H](N(C2=NC=NC(N)=C2N3)C3=O)O[C@@H]1COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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