Fig. 1 · Structure
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DMTr-LNA-C(Bz)-3-CED-phosphoramidite
Purine Nucleoside Analog
DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog designed for the synthesis of oligonucleotides. This compound is essential for incorporating locked nucleic acid (LNA) modifications into oligonucleotide sequences, enhancing thermal stability and binding affinity. It is applicable in various research areas, including gene regulation studies, antisense therapy, and the development of molecular probes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 206055-78-9 |
| Applications | Purine Nucleoside Analog |
| Formula | C47H52N5O9P |
| Molecular Weight | 861.92 |
| SMILES | [H][C@@]12[C@H](N3C(N=C(NC(C4=CC=CC=C4)=O)C=C3)=O)O[C@@]([C@H]2OP(N(C(C)C)C(C)C)OCCC#N)(COC(C5=CC=C(OC)C=C5)(C6=CC=CC=C6)C7=CC=C(OC)C=C7)CO1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.