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DMTr-2'-O-C6-rG(iBu)-3'-CE-phosphoramidite

Nucleoside Analog

DMTr-2'-O-C6-rG(iBu)-3'-CE-phosphoramidite is a nucleoside analog primarily utilized in the synthesis of oligonucleotides. This phosphoramidite derivative features a 2'-O-modification, enhancing compatibility with various biological applications. It serves as a key building block in the development of antisense oligonucleotides, RNA interference studies, and other nucleic acid-based research initiatives.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2642321-69-3
Applications	Nucleoside Analog
Formula	C₅₀H₆₆N₇O₉P
Molecular Weight	940.07
SMILES	COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](OCCCCCC)[C@H](N(C=N5)C6=C5C(N=C(NC(C(C)C)=O)N6)=O)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.