Fig. 1 · Structure
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1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite
Thymidine Analog
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog that acts as an effective substrate for DNA polymerases. This compound exhibits incorporation activity into replicated DNA, making it a valuable tool for labeling and tracking DNA synthesis in various biological studies. Its unique structural modifications enable researchers to explore nucleotide dynamics and cellular activities related to DNA replication.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 208193-48-0 |
| Applications | Thymidine Analog |
| Formula | C40H48FN4O8P |
| Molecular Weight | 762.80 |
| SMILES | O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]2F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.