5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu)

Catalog No.: A56642
Nucleoside Analog
5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu) is a nucleoside analog specifically designed for use in nucleic acid synthesis. This compound functions as a protected monomer, facilitating the incorporation of modified guanosine units into oligonucleotide sequences. Its unique structural features enhance stability and enzymatic properties, making it an essential reagent for researchers focused on developing therapeutics and diagnostic tools involving RNA and DNA.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu) is a nucleoside analog specifically designed for use in nucleic acid synthesis. This compound functions as a protected monomer, facilitating the incorporation of modified guanosine units into oligonucleotide sequences. Its unique structural features enhance stability and enzymatic properties, making it an essential reagent for researchers focused on developing therapeutics and diagnostic tools involving RNA and DNA.
Product Information
Catalog NumA56642
FormulaC36H37N5O8
Molecular Weight667.71
CAS Number206055-72-3
SMILESO[C@H]1[C@](OC2)([H])[C@H](N3C4=C(C(N=C(N4)NC(C(C)C)=O)=O)N=C3)O[C@]12COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2