DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite

Catalog No.: A56631
Nucleoside Analog
DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite is a nucleoside analog designed for efficient nucleic acid synthesis. This compound serves as a key monomer for the incorporation of modified ribonucleotides into oligonucleotides, enhancing stability and bioactivity. It is particularly useful in the development of RNA therapeutics, probes, and various molecular biology applications, facilitating precise manipulation of RNA structures.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite is a nucleoside analog designed for efficient nucleic acid synthesis. This compound serves as a key monomer for the incorporation of modified ribonucleotides into oligonucleotides, enhancing stability and bioactivity. It is particularly useful in the development of RNA therapeutics, probes, and various molecular biology applications, facilitating precise manipulation of RNA structures.
Product Information
Catalog NumA56631
FormulaC51H51N6O10PS
Molecular Weight971.02
CAS Number2379296-27-0
SMILESCOC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](O[P@]5N6[C@@](CCC6)([H])[C@@H](O5)CS(=O)(C7=CC=CC=C7)=O)[C@@H](OC)[C@H](N8C9=NC=NC(NC(C%10=CC=CC=C%10)=O)=C9N=C8)O4
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