Fig. 1 · Structure

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DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-phosphoramidite

Nucleoside Analog

DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer facilitates the incorporation of modified nucleotides into oligonucleotide sequences, enhancing the stability and functionality of nucleic acids. It is particularly valuable in the development of antisense oligonucleotides and RNA-based therapeutics.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 771494-03-2
Applications Nucleoside Analog
Formula C45H60N7O7PSi
Molecular Weight 870.06
SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N2N=NC3=CN=CN=C32)O[C@@H]1COC(C(C=C4)=CC=C4OC)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)OCCC#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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