Catalog No.
Product Name
Application
Product Information
Citations
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Acyltransferase Inhibitor
Amidepsine D is an acyltransferase inhibitor derived from the fungal metabolite isolated from the culture broth of Humicola sp. FO-2942. It specifically inhibits diacylglycerol acyltransferases (DGAT), playing a crucial role in lipid metabolism regulation. This compound is valuable for research applications focused on examining lipid biosynthesis pathways and exploring potential therapeutic targets in metabolic disorders. -
ACAT Inhibitor
Lateritin is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), derived from the mycelial cake of Gibberella lateritium IFO 7188. This compound exhibits significant biological activity by inhibiting the growth of various human cancer cell lines, as well as displaying antibacterial effects against gram-positive bacteria and antifungal activity against Candida albicans. Lateritin is a valuable tool for research in cancer therapeutics and the study of lipid metabolism. -
ACAT Inhibitor
Glisoprenin A is an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), targeting cholesterol metabolism. It has demonstrated significant activity in inhibiting the formation of appressorium on hydrophobic surfaces in the fungal pathogen Magnaporthe grisea. This compound is valuable for research into fungal plant pathogens and cholesterol metabolism dynamics. -
ACAT Inhibitor
Glisoprenin D is an ACAT inhibitor that selectively targets cholesterol acyltransferase, thereby influencing lipid metabolism. It has been shown to inhibit the formation of appressorium on the hydrophobic surfaces of Magnaporthe grisea, making it a valuable tool for studying fungal pathogenesis and plant-fungal interactions. This compound has potential applications in both basic and applied research within mycology and plant sciences. -
ACAT Inhibitor
Glisoprenin C is a selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), which plays a crucial role in cholesterol metabolism. By inhibiting ACAT, Glisoprenin C effectively disrupts cholesterol esterification, impacting the pathogenicity of organisms such as Magnaporthe grisea by preventing appressorium formation on hydrophobic surfaces. This compound is valuable in studying cholesterol-related pathways and evaluating potential therapeutic strategies against fungal pathogens. -
ACAT Inhibitor
Glisoprenin E is an ACAT inhibitor that effectively inhibits cholesterol acyltransferase activity. This compound has demonstrated biological activity by preventing the formation of appressorium on hydrophobic surfaces in the phytopathogen Magnaporthe grisea. Its applications are significant in studying fungal pathogenicity and the role of lipid metabolism in plant-fungal interactions. -
Fungal Phytotoxin
Radicinin is a fungal phytotoxin that functions as a target-specific bioherbicide, effectively inhibiting the growth of invasive Buffelgrass (Cenchrus ciliaris). This compound exhibits significant biological activity by disrupting the metabolic processes of the plant, making it a valuable tool for managing invasive species. It is primarily applied in research focused on ecological restoration and integrated weed management strategies. -
Mycotoxin Metabolite
Asticolorin C is a mycotoxin metabolite derived from the fungus Aspergillus multicolor. It exhibits biological activity by potentially influencing cellular processes related to mycotoxin detoxification and metabolism. This compound serves as a valuable tool in research applications focusing on mycotoxin biology, fungal ecology, and the assessment of mycotoxin contamination in food and agricultural products. -
Mycotoxin Metabolite
Asticolorin A is a mycotoxin metabolite derived from Aspergillus multicolor. It exhibits biological activity related to fungal metabolism and can be utilized in research exploring mycotoxin effects and toxicology. This compound may serve as a valuable tool for studying the biochemical pathways involved in mycotoxin metabolism and the impact of fungal metabolites on health. -
Antibiotic
Cefonicid monosodium is a long-acting cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It possesses broad-spectrum antimicrobial activity, effectively combating a range of Gram-positive and Gram-negative bacteria. Additionally, Cefonicid acts as a noncompetitive inhibitor of class I β-lactamase, with a Ki value of 0.8 μM, making it a valuable reagent for research on bacterial infections and antibiotic resistance. -
Bacterial Glycoside Hydrolase Activator
4-Ethoxyquinazoline is a selective activator of bacterial glycoside hydrolases, demonstrating an AC50 of 3.5 mM. This compound enhances the enzymatic activity of glycoside hydrolases, supporting research focused on bacterial metabolism and cell wall remodeling. Its role in modulating enzyme activity makes it a valuable tool for studies on bacterial physiology and potential therapeutic applications. -
Bacterial Metabolite
Corynecin V is a chloramphenicol-like bacterial metabolite that targets bacterial protein synthesis. It exhibits antibacterial activity against a range of gram-positive bacteria by inhibiting peptidyl transferase activity in the ribosome. This compound is of significant interest in microbiological research and antibiotic development, providing insights into novel therapeutic strategies against antibiotic-resistant strains. -
Griseofulvin Metabolite
6-O-Demethyl griseofulvin is a significant metabolite of Griseofulvin, primarily acting on fungal cell division by inhibiting microtubule formation. This compound demonstrates antifungal activity, making it valuable in studying the efficacy of antifungal treatments and the metabolic pathways involving Griseofulvin. Its applications extend to research focused on dermatophyte infections and fungal resistance mechanisms. -
Metabolite
BTS44596 (Prochloraz-desimidazole-formylamino) is a key metabolite of the antifungal agent Prochloraz, primarily targeting regulatory monitoring applications. This compound serves as a critical target analyte for assessing Prochloraz residue limits in fruits and vegetables. Additionally, it facilitates simultaneous detection using LC-MS/MS methodology, making it an essential tool for food safety and environmental studies. -
α-glucosidase Inhibitor
CM-10-18 is a potent inhibitor of α-glucosidases I and II, demonstrating significant activity in vitro and in animal models. This compound also exhibits antiviral properties by inhibiting dengue virus (DENV) infection in cultured human cells, while effectively reducing peak viremia in mice. CM-10-18 is valuable for research applications related to glycosidase inhibition and viral pathogenesis. -
Anti-Viral Agent
IHVR-17028 is a broad-spectrum antiviral agent that primarily targets endoplasmic reticulum α-glucosidase I. It demonstrates significant antiviral activity against various viruses, including Bovine viral diarrhea virus (BVDV), Tick-borne choriomeningitis virus (TCRV), and Dengue virus (DENV), with EC50 values of 0.4 μM, 0.26 μM, and 0.3 μM, respectively. With an IC50 of 0.24 μM, it effectively inhibits ER α-glucosidase I, making it a valuable tool for research into infectious diseases. -
Fungicide
Cyazofamid is a fungicide that primarily targets the impairment of ATP production in fungal cells. It acts by inhibiting organic cation transporter 3 (OCT3) and organic anion transporter 1 (OAT1), with IC50 values of 1.54 μM and 17.3 μM, respectively. This compound is utilized in research to explore mechanisms of fungicidal activity and to develop effective strategies for managing fungal diseases in agricultural settings. -
Fungicide
Fenaminstrobin is a strobilurin fungicide that targets the cytochrome bc1 complex within the mitochondrial respiratory chain, leading to the inhibition of ATP production. This compound demonstrates significant biological activity in controlling a variety of fungal diseases, including Fusarium ear rot, downy mildew, rice blast, and pear scab. Additionally, Fenaminstrobin exhibits acute toxicity to the aquatic organism Daphnia magna, making it relevant for ecological impact studies. Its application in agricultural research focuses on crop protection and disease management in various plant systems. -
Antifungal Agent
Dapaconazole is an antifungal agent that primarily inhibits the activity of sterol 14α-demethylase cytochrome P450, exhibiting an IC50 of 1.4 μM. This inhibition disrupts the synthesis of ergosterol, a critical component of fungal cell membranes, thereby exerting antifungal effects. Dapaconazole is applicable in research focused on fungal infections and the development of novel antifungal therapies. -
Antifungal Agent
VT-1598 tosylate is an orally active antifungal agent that selectively inhibits CYP51, demonstrating effective antifungal properties against Candida auris. Additionally, VT-1598 tosylate serves as a click chemistry reagent, incorporating an alkyne group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This dual functionality positions VT-1598 tosylate as a valuable tool in both antifungal research and synthetic chemistry applications. -
CYP51 Inhibitor
CYP51-IN-21 is a potent inhibitor of cytochrome P450 51 (CYP51), demonstrating significant antifungal activity against various pathogenic fungi, including drug-resistant strains. By targeting CYP51, CYP51-IN-21 disrupts the biosynthesis of essential sterols, impairing fungal growth and viability. Additionally, CYP51-IN-21 effectively inhibits the formation of fungal biofilms, making it a valuable candidate for research in antifungal therapeutics and biofilm-related studies. -
Fungal Terpenoid
Terretonin is a fungal terpenoid derived from Aspergillus terreus, primarily targeting enzymatic pathways involved in its biosynthesis. Its production involves a complex sequence of reactions, including oxidation by cytochrome P450 Trt6, isomerization by Trt14, and final processing by the non-heme iron-dependent dioxygenase Trt7. This compound exhibits significant biological activity with potential applications in pharmaceutical research, particularly as a lead for developing novel antifungal agents. -
Bacterial Peptide Lipid Substance
D-Allothreonine is the D stereoisomer of allothreonine, targeting bacterial peptide lipid substances. This compound can be specifically oxidized by D-amino acid oxidase, illustrating its unique reactivity compared to its L counterpart. D-Allothreonine plays a crucial role as a component of bacterial polysaccharides, making it valuable for studies on bacterial pathogenicity, antigenic variation, and mechanisms of drug resistance. Its specific biochemical interactions and applications in microbiological research highlight its significance in advancing understanding of bacterial behavior and treatment strategies. -
Anticancer/Antibacterial agents
Methyl 6-bromo-1H-indole-3-carboxylate is an indole derivative with notable anticancer and antibacterial properties. This compound demonstrates effective growth inhibition against Staphylococcus epidermidis, making it a valuable tool in studies of bacterial infections and tumorigenesis. Its diverse biological activities facilitate research in the fields of oncology and infectious diseases. -
E. coli Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a potent E. coli metabolite that serves as a valuable tool for studying the PurE enzyme's active site. It is instrumental in investigating the de novo purine synthesis pathway in fungi, allowing researchers to elucidate metabolic processes and potential enzymatic regulation. Additionally, CAIR can aid in further understanding bacterial and fungal metabolism, contributing to broader applications in microbiology and biochemistry research. -
Metal Chelator
Calcium disodium edetate hydrate is a metal chelator that effectively targets and binds divalent metal ions, including manganese (Mn2+). Its biological activity includes the disruption of mitochondrial function and interference with carbohydrate metabolism, particularly in the synthesis of pyruvate during glycolysis. Additionally, Calcium disodium edetate hydrate exhibits antifungal properties by inhibiting the growth of Penicillium digitatum and delaying conidial germination. This compound is valuable for research focused on controlling citrus green mold and enhancing host defense mechanisms in citrus fruits. -
Nonionic Surfactant
Polyoxyl 40 stearate (PEG 40 stearate) functions as a nonionic surfactant, synthesized through the esterification of stearic acid with polyethylene glycol containing approximately 40 ethoxy units. It exhibits key biological activity in the formulation of pharmaceutical preparations and nanodrug carriers, facilitating emulsification and stabilization of active compounds. Applications include its use as a matrix component in solid lipid nanoparticles for the controlled release of encapsulated antifungal drugs, as well as serving as a base material for vaginal drug delivery systems, where it can be modified with acryloyl chloride to introduce polymerizable groups. -
Glucosaminide Substrate
VLPA-GlcNAc is a chromogenic glucosaminide substrate that serves as a valuable tool for the identification of Candida species. It can be utilized in the preparation of specialized agar media, facilitating the differentiation of Candida strains based on their enzymatic activity. This reagent is essential in microbiological research and diagnostics, particularly in clinical settings where rapid identification of fungal pathogens is crucial. -
Chlorinated Phenol Active Substance
4,5-Dichloroguaiacol is a chlorinated phenol active substance known for its role in various biochemical applications. It exhibits significant antibacterial and antifungal properties, making it valuable in studies focused on microbial inhibition. This compound is commonly utilized in research involving antimicrobial assays and as a standard in environmental toxicology. -
Antibacterial Agent
3,6-Diaminoacridine hydrochloride is an antibacterial agent that targets bacterial cell membranes, disrupting their integrity. This compound exhibits significant antibacterial activity, making it a valuable reagent for microbial studies and preservation applications. Its utility extends to research involving antibiotic resistance and the evaluation of antibacterial compounds. -
Chlorophenolic Compound
3,4,5-Trichlorosyringol is a chlorophenolic compound that is synthesized through the chlorination of syringol in carbon disulfide (CS2). This compound exhibits anti-fungal and anti-bacterial activities, making it useful for research involving microbial growth inhibition. It is applicable in studies focused on phytopathology, environmental microbiology, and the development of antimicrobial agents. -
Viral Enzyme Neuraminidase Substrate
Submandibular mucin serves as a substrate for the viral enzyme neuraminidase, characterized by its high molecular weight glycoprotein structure. This compound exhibits key biological activities relevant to the study of viral infections, particularly in the context of influenza research. Its applications include investigating the enzymatic activity of neuraminidase and examining mucin interactions with viral pathogens. -
Nutritional Additive
Corn steep liquor serves as a nutritional additive, primarily utilized in liquid culture media for fungal cultivation. It enhances the production of mycelial growth and secondary metabolites, supporting research in microbial metabolism and biotechnology applications. This by-product of corn processing provides essential nutrients that promote optimal fungal development and yield. -
Biotinylation Reagent
Biotin-DADOO is a biotinylation reagent that facilitates the covalent attachment of biotin to various substrates. It acts as an amino component in the nucleophilic ring-opening reaction of epoxidized ω-double bonds, enabling the synthesis of biotinylated inhibitor derivatives. Additionally, Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives and is utilized in the development of biotin-estradiol conjugates for enzyme immunoassays. This reagent is also relevant in the study of influenza A research. -
Immune System Modulator
Zymosan (ZM), 95% is an immune system modulator derived from yeast cell walls that primarily targets TLR-2, TLR-4, and Dectin-1 receptors. It activates downstream signaling pathways that enhance TLR-2, TLR-4, and TNF-α mRNA expression, leading to increased serum TNF-α levels and improved splenocyte viability in murine models. Zymosan (ZM), 95% has been shown to inhibit melanoma growth, modulate macrophage marker gene expression, and induce pro-inflammatory factor production in human corneal cells. Additionally, it serves as a drug carrier and supports fibroblast cell attachment in hydrogel formulations, making it a valuable tool for research on melanoma, tumors, fungal keratitis, and ocular surface inflammatory disorders. -
Immunity Enhancer
Tremella polysaccharide, a high molecular weight fungal polysaccharide, functions primarily as an immunity enhancer. This compound exhibits notable biological activity by modulating immune responses, making it relevant for research applications focused on addressing leukopenia induced by chemotherapy and radiotherapy. Its cosmetic grade designation further supports its potential in skin health and immune support formulations. -
Organosulfur Compound
Thiosalicylic acid, an organosulfur compound featuring both sulfhydryl and carboxyl functional groups, primarily functions as a desulfurizing agent. This compound is utilized as a ligand in the synthesis of azosulfonamide derivatives, which exhibit antibacterial and antifungal properties. Additionally, thiosalicylic acid facilitates the formation of metal chelates, specifically with Fe3+, Cu2+, and Hg2+, enhancing its versatility in various biochemical applications. -
Pyrrole Compound
Methyl 5-bromo-1H-pyrrole-2-carboxylate is a pyrrole compound with a unique brominated structure. Its primary biological activities include various antimicrobial and antifungal properties. This reagent is useful in chemical research focused on synthesizing novel pyrrole derivatives and studying their potential applications in pharmaceuticals and biologically active compounds. -
Antifungal/Antibacterial Agent
1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol exhibiting diverse biological activities, including antifungal, antibacterial (active against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer, and antioxidant effects. It can be isolated from the leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol demonstrates significant inhibitory activity against pathogenic fungi and shows potential efficacy in controlling pepper anthracnose in phytopathological studies. This compound is a valuable research tool for investigations in fungal infections, oncology, and oxidative stress-related disorders.
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Antileishmanial Agent
N-(2-Hydroxypropyl)methacrylamide functions as a key building block for the synthesis of copolymers aimed at targeted drug delivery in the treatment of visceral leishmaniasis (VL). This compound enhances the efficacy of antileishmanial agents by facilitating their selective transport to the affected tissues. Its application in polymer chemistry supports advanced therapeutic approaches in combating leishmaniasis. -
Bacterial Labeling
3-Azido-D-alanine hydrochloride is an azido-modified amino acid that serves as a versatile reagent for click chemistry applications, particularly in bacterial labeling. The presence of the azide group allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified substrates, making it a valuable tool in bioconjugation and chemical biology research. -
Bacterial Labeling
3-Azido-D-alanine is an azido-modified analog of D-alanine that serves as a valuable tool for bacterial labeling applications. It features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, 3-Azido-D-alanine can engage in ring strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. This reagent is ideal for studies involving click chemistry in microbial systems. -
Anticancer Agent
Antitumor Agent-160 is a derivative of the antifungal compound phenalenone, serving as an anticancer agent. It exhibits significant antitumor activity, making it a valuable tool in cancer research. Its potential applications include the study of cancer cell proliferation and the evaluation of therapeutic strategies in oncological research. -
Detection Substrate
5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside functions as a sensitive enzyme substrate with chemiluminescent properties. It facilitates the detection of various enzymatic activities, making it suitable for diagnostic assays aimed at identifying bacterial and fungal infections, as well as other diseases. Its utility in research applications enhances the reliability of assays in clinical microbiology and molecular diagnostics. -
Chlorinated Phenol
Tetrachloroguaiacol is a chlorinated phenol primarily formed during the chlorine bleaching of wood pulp. It exhibits significant antibacterial and antifungal activities, making it relevant for studies in environmental science and biochemistry. This compound serves as a valuable reagent in research focused on the effects of chlorinated compounds on biological systems and their potential environmental impact. -
α,β-unsaturated Fatty Acid
2-Decenoic acid is an α,β-unsaturated fatty acid known to inhibit plant pollen germination and pollen tube elongation. This compound exhibits significant biological activity, making it a valuable tool for research in plant reproductive biology. Additionally, its antimicrobial properties suggest potential applications in developing antifungal and antibacterial agents. -
Redox Isomer
Neopatulin is a redox isomer and a critical biogenetic precursor of the antibiotic patulin, commonly produced by various fungal species. This compound plays a significant role in studies pertaining to antibiotic synthesis and fungal metabolism. Neopatulin can be synthesized through methods such as Lewis acid-catalyzed aldol reactions or utilizing 2-formyl-1,3-dithiane in conjunction with 2-(tert-butyldimethylsiloxy)-4-[(tert-butyldimethylsiloxy)-methyl]furan, making it a valuable reagent for chemical research applications. -
Phenolic Compound
Daphneolone is a phenolic compound known for its potential antifungal properties against plant pathogenic fungi. Isolated from the roots of Daphneodora, this compound is valuable for research into natural antifungal agents and plant defense mechanisms. Its analogues may offer insights into the development of eco-friendly agricultural solutions. -
Oxylipin
8(R),11(S)-DiHODE is a fungal oxylipin that primarily targets lipid signaling pathways. It is known to play a role in modulating inflammatory responses and cell signaling processes. This compound is of particular interest in research applications related to metabolic diseases, inflammation, and fungal biology, providing insights into the biochemical pathways influenced by oxylipins. -
Active Compound
Nikkomycin J is an active compound that functions as an inhibitor of chitin synthase, targeting fungal cell wall biosynthesis. Its primary biological activity includes antifungal effects, making it particularly valuable in research related to fungal infections and the development of antifungal therapies. Nikkomycin J is utilized in studies focused on fungal pathogenesis and drug resistance mechanisms.
