Catalog No.
Product Name
Application
Product Information
Citations
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Azasterol
Fluoro azasterol is an azasterol derivative that functions as a potent inhibitor of parasitic and fungal growth. This compound exhibits significant biological activity against various pathogens, making it a valuable tool for research in the fields of parasitology and mycology. Its applications include studying the mechanisms of anti-parasitic and antifungal action, as well as exploring potential therapeutic uses in infectious disease models. -
Fluorescent Dye
Primulin is a fluorescent dye that exhibits strong binding affinity for albumin, making it a valuable tool in various analytical and biological studies. This compound effectively labels plant cell walls and distinguishes between live and dead spermatozoa through distinct fluorescence patterns. In neurobiology, Primulin serves as a retrograde axonal tracer, while its derivatives demonstrate inhibitory activity against HCV NS3 and interference with dengue virus NS3-mediated ATP hydrolysis. Additionally, Primulin disrupts HCV replicase assembly, highlighting its potential in virology research applications. -
Bacterial Inhibitor
Ethionamide is a second-line anti-tuberculosis agent that acts primarily by inhibiting the synthesis of mycolic acids in Mycobacterium tuberculosis. This compound demonstrates significant antibacterial activity and is effective when administered orally. Ethionamide is utilized in research applications focused on tuberculosis treatment resistance mechanisms and the development of novel therapeutics against mycobacterial infections. -
Antibiotic
Fenbendazole is an orally active benzimidazole compound that primarily targets tubulin, acting as a microtubule destabilizing agent. It exhibits a broad antiparasitic activity by disrupting microtubule equilibrium in helminths. Additionally, fenbendazole is known for its anti-proliferative effects, inducing apoptosis and causing cell-cycle arrest in various cancer models. Its antitumor properties have been demonstrated in mice xenografted with wild-type p53, making it a valuable reagent for exploring mechanisms of cancer therapy. -
Bacterial Inhibitor
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. This compound exhibits potent antibacterial activity against a wide range of gram-negative and some gram-positive bacteria. Fleroxacin is suitable for research applications focused on the elucidation of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Antibiotic
Nalidixic acid is a quinolone antibiotic that primarily targets DNA gyrase and topoisomerase IV, interfering with bacterial DNA replication. It exhibits a bacteriostatic effect at lower concentrations and becomes bactericidal at higher concentrations. Nalidixic acid is effective against both gram-positive and gram-negative bacteria, making it valuable for studies involving bacterial infections and resistance mechanisms in microorganisms. -
Bacterial Inhibitor
Nitrofurazone is a nitro-aromatic antibacterial compound primarily targeting bacterial DNA and RNA synthesis. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it suitable for a variety of microbiological research applications. Nitrofurazone is often utilized in studies assessing antimicrobial resistance and the efficacy of antibiotic treatments. -
Antibiotic
Secnidazole is an orally active azole antibiotic that primarily targets bacterial quorum sensing (QS) mechanisms. By inhibiting acylhomoserine lactones, Secnidazole attenuates the virulence of Pseudomonas aeruginosa and exhibits antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria. This reagent is valuable for research applications related to diseases such as amoebiasis, giardiasis, and bacterial vaginitis, facilitating studies on their pathogenesis and treatment. -
Sulfonamide Antibiotic
Sulfadiazine is a sulfonamide antibiotic that inhibits bacterial folic acid synthesis by competitively antagonizing para-aminobenzoic acid (PABA). It exhibits antimalarial properties and is primarily utilized in research involving toxoplasmosis. Sulfadiazine's mechanism of action makes it a valuable tool for studying sulfamethoxazole efficacy and the interplay of antibiotics in parasitic infections. -
Antibiotic
Sulfameter, a sulfonamide antibiotic, exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Its long-acting formulation makes it suitable for research applications targeting bacterial infections, particularly in respiratory and urinary tracts. This compound serves as a valuable tool in the study of antibiotic efficacy and resistance mechanisms in various pathogens. -
Sulfathiazole Antibiotic
Sulfamethizole is a sulfathiazole antibiotic that inhibits the synthesis of folic acid and thymine, thereby affecting bacterial growth. It demonstrates antibacterial activity against Escherichia coli in urinary tract infections, though it is ineffective against sulII gene-positive strains. This compound is valuable for research into the mechanisms of urinary tract infections and the bioluminescence of Photobacterium phosphoreum. -
Sulfonamide Antibiotic
Sulfamethoxazole is a sulfonamide antibiotic that exerts its antibacterial effect by inhibiting bacterial folate metabolism. It achieves this by competitively interfering with 4-Aminobenzoic acid (PABA) at the active site of dihydropteroate synthetase and dihydropteroate reductase. This compound is primarily utilized in the research of urinary tract infections (UTIs), prostatitis, and bronchitis, making it a valuable tool for studying antibiotic resistance and bacterial infections. -
Antibiotic
Sulfanilamide is a potent sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase. This compound demonstrates significant biological activity against various pathogens, including inhibition of the lymphogranuloma venereum virus. Additionally, sulfanilamide acts as a carbonic anhydrase inhibitor, making it useful in a range of biochemical research applications, particularly in studies involving antibiotic resistance and enzyme dynamics. -
Antibacterial Antibiotic
Tebipenem pivoxil is an orally active antibacterial antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis. Its efficacy against a range of pathogenic bacteria makes it a valuable tool for research applications in microbiology and pharmacology, particularly in studying antibiotic resistance mechanisms and developing new therapeutic strategies. -
Bacterial Inhibitor
Teicoplanin is a glycopeptide antibiotic primarily targeting Gram-positive bacteria, demonstrating potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus aureus. In addition to its antibacterial properties, teicoplanin exhibits antiviral effects against HIV-1, SARS-CoV-1, and SARS-CoV-2. This versatile compound is utilized in research related to bacterial resistance and viral infections, making it a valuable tool for studying antimicrobial efficacy and therapeutic interventions. -
HBV Replication Inhibitor
Telbivudine is an orally active thymidine nucleoside analog that acts as an inhibitor of hepatitis B virus (HBV) replication. Its potent antiviral activity makes it valuable in the study of HBV-related pathologies and the development of antiviral therapies. This compound serves as a significant tool for researchers investigating HBV dynamics and therapeutic interventions. -
Bacterial Inhibitor
Tobramycin is a broad-spectrum aminoglycoside antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits significant antibacterial activity against a variety of Gram-negative and some Gram-positive bacteria. Tobramycin is particularly effective in research applications focused on infections caused by Pseudomonas aeruginosa, including studies related to pneumonia. Its efficacy makes it a valuable reagent in microbial pathogenesis and antibiotic resistance research. -
Antibacterial Agent
Mafenide hydrochloride is a sulfonamide-type antimicrobial agent that targets bacterial infections. It exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, primarily through the inhibition of nucleotide synthesis. Mafenide hydrochloride is commonly utilized in the treatment of burn wounds, making it a valuable reagent in research focused on wound healing and infection control. -
Influenza Virus Inhibitor
Oseltamivir is an orally active neuraminidase inhibitor targeting the influenza virus. It demonstrably inhibits various strains of influenza, including A/H3N2, A/H1N2, A/H1N1, and B, with mean IC50 values of 0.67 nM, 0.9 nM, 1.34 nM, and 13 nM, respectively. This compound is essential for studying antiviral strategies and evaluating the efficacy of flu treatments in laboratory settings. -
Cephalosporin Antibiotic
Cephalexin is a semisynthetic cephalosporin antibiotic known for its broad-spectrum activity against numerous gram-positive and gram-negative bacteria. It functions primarily by inhibiting penicillin-binding proteins (PBPs), which are essential for bacterial cell wall synthesis. This compound is widely utilized in research related to bacterial infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. Its oral bioavailability and efficacy make it a valuable tool in microbiological studies. -
Parasite Inhibitor
Albendazole sulfoxide, the principal active metabolite of Albendazole, acts as a potent inhibitor of parasite growth. It demonstrates significant anti-parasitic activity against Echinococcus multilocularis metacestodes, making it valuable in the study of parasitic infections and potential therapeutic interventions. This compound is utilized in research focused on parasitology and drug efficacy against helminthic diseases. -
Parasite Inhibitor
Oxfendazole is a sulfoxide derivative of fenbendazole that targets parasitic organisms through inhibition of energy metabolism. Its primary biological activity is the effective combat against a broad spectrum of parasites. This compound is utilized in research focused on parasitology and can also be studied for its potential effects in tumor promotion investigations. -
Antibiotic
Amoxicillin is a beta-lactam antibiotic that targets bacterial cell wall synthesis. It exerts its antimicrobial activity by inhibiting the peptidoglycan biosynthesis necessary for cell wall formation, leading to impaired cell growth and division. Amoxicillin is widely used in various research applications to study bacterial infections and resistance mechanisms. -
Bacterial Inhibitor
Ampicillin sodium is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent for microbiological research. Ampicillin sodium is commonly used in cell culture and for selecting genetically modified organisms, as well as in the study of bacterial resistance mechanisms. Its ability to inhibit bacterial growth supports investigations into antibiotic efficacy and microbial interactions. -
Aminoglycoside Antibiotic
Amikacin hydrate is an aminoglycoside antibiotic that serves as a semisynthetic analog of kanamycin. It exhibits bactericidal activity by binding to the 30S and 50S ribosomal subunits in bacteria, ultimately inhibiting protein synthesis. This reagent is particularly effective against a wide range of Gram-negative bacteria, including strains resistant to gentamicin and tobramycin, as well as infections caused by susceptible Nocardia and nontuberculous mycobacteria. Amikacin hydrate is commonly utilized in research focused on combating antibiotic-resistant infections and studying mechanisms of antibiotic action. -
Antibiotic
Bacitracin Zinc is a complex of Bacitracin and zinc ions, functioning primarily as an antibiotic with bactericidal activity. This polypeptide antibiotic is effective in causing damage to bacterial DNA and deoxyribose, making it a valuable agent in combating microbial infections. Additionally, Bacitracin Zinc has been shown to enhance gut microbiota composition in broiler and beef cattle, contributing to improved overall health and growth performance in livestock research applications. -
Bacterial Inhibitor
Cefoperazone is a semisynthetic cephalosporin that functions as a bacterial inhibitor by interfering with cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. This reagent is commonly employed in microbiological research to study bacterial infections and assess the efficacy of antimicrobial agents. -
Antibiotic
Carbenicillin disodium is a broad-spectrum semi-synthetic penicillin antibiotic targeting gram-negative bacteria. It exerts its antibacterial activity by inhibiting cell wall synthesis, making it effective in various microbiological applications. Due to its low toxicity, it is also suitable for use in plant tissue research. -
Antibiotic
Dimetridazole is a nitroimidazole antibiotic that primarily targets protein synthesis in various bacteria, including Campylobacter jejuni. It exhibits genotoxic properties, making it a valuable tool in research related to protozoal and bacterial infections. Its ability to disrupt microbial growth provides insights into pathogenic mechanisms and supports the development of therapeutic strategies. -
Bacterial Inhibitor
Erdosteine functions as a bacterial inhibitor by inhibiting lipopolysaccharide (LPS)-induced activation of NF-κB. This compound exhibits muco-modulatory, anti-bacterial, anti-inflammatory, and antioxidant properties. Erdosteine is primarily utilized in research applications focused on respiratory disorders and inflammation, supporting the study of therapeutic interventions in these areas. -
Bacterial Inhibitor
Erianin is a bacterial inhibitor that exhibits potent anticancer properties by inhibiting indoleamine 2,3-dioxygenase (IDO). This activity contributes to its ability to suppress tumor angiogenesis, making it a valuable compound in cancer research. Erianin's dual role as an antipyretic and analgesic further broadens its potential applications in therapeutic studies. -
HIV Inhibitor
Sennoside A is an anthraquinone glycoside derived from the senna plant (Cassia angustifolia) that exhibits inhibitory activity against HIV-1. This compound demonstrates an IC50 value of 3.8 μM in preventing HIV-1 replication and effectively inhibits HIV-1 reverse transcriptase-related DNA polymerase and ribonuclease H, with IC50 values of 1.9 μM and 5.3 μM, respectively. Sennoside A serves as a valuable tool in antiviral research, particularly in studies of HIV-1 replication mechanisms and potential therapeutic interventions. -
Bacterial Inhibitor
Allicin (diallyl thiosulfinate) is a potent bacterial inhibitor derived from garlic extracts, primarily responsible for the antimicrobial properties of garlic. It demonstrates significant antimicrobial activity against a wide range of microorganisms, including antibiotic-resistant strains, making it a valuable reagent for research in microbiology and pharmacology. Allicin is commonly utilized in studies investigating natural antibacterial compounds and their mechanisms of action. -
Antibacterial Drug
p-Anisic acid, also known as 4-Methoxybenzoic acid, acts primarily as a tyrosinase inhibitor. It exhibits multiple biological activities, including antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, and anti-diabetic effects. This compound is also utilized as a preservative in cosmetic formulations, making it relevant for research in medicinal chemistry and cosmetic science. -
Antibiotic
Ertapenem is a broad-spectrum β-lactam antibiotic, characterized by its long-acting properties and efficacy against a wide range of anaerobic bacteria. With a minimum inhibitory concentration (MIC) of 0.12 μg/mL, it demonstrates significant anti-anaerobic activity. Ertapenem is utilized in research focused on severe bacterial infections affecting various human systems, including the skin, lungs, gastrointestinal tract, pelvis, and urinary tract. -
Antitumor Antibiotic
Quinocarcin is a potent antitumor antibiotic that primarily targets and inhibits DNA, RNA, and protein synthesis in Bacillus subtilis. This compound demonstrates significant cytotoxic activity against various cancer cell lines, making it a valuable tool in cancer research. Its unique mechanism of action supports its applications in studying tumorigenesis and the development of novel therapeutic strategies. -
Bacterial Inhibitor
Evoxine, also known as Haplophytin B, is a bacterial inhibitor that selectively targets CO2-induced immunosuppression. It demonstrates significant antimicrobial activity, particularly against common pathogens such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, as evidenced by its performance in minimum inhibitory concentration (MIC) assays. Evoxine also inhibits the expression of pro-inflammatory cytokines such as interleukin-6 and chemokine CCL2 in human THP-1 macrophages, indicating its potential utility in therapeutic applications and crude drug preparations, particularly in the context of traditional medicine in West Africa. -
HBV Inhibitor
Catalpol, an iridoid glycoside derived from Rehmannia glutinosa, primarily targets hepatitis B virus (HBV) inhibition. It exhibits a broad range of biological activities including neuroprotection, hypoglycemic effects, anti-inflammatory properties, and antioxidant effects. Additionally, Catalpol demonstrates potential in anti-cancer and anti-spasmodic applications, making it valuable for various research contexts focusing on viral infections and related therapeutic interventions. -
Antibiotic
Tetracycline hydrochloride is a broad-spectrum antibiotic targeting bacterial protein synthesis. It demonstrates antibacterial activity against a wide array of microorganisms, including gram-positive and gram-negative bacteria, as well as chlamydiae, mycoplasmas, and rickettsiae. This reagent is suitable for research applications involving bacterial infections and studies related to antibiotic resistance mechanisms. -
Active Component of Radix
Phytolaccagenin is a triterpenoid saponin that is the active component of Radix Phytolaccae. This compound exhibits significant antifungal and anti-inflammatory activities, making it a valuable reagent for research in pharmacology and toxicology. Its lower toxicity profile enhances its potential as a candidate for therapeutic applications and further biological studies. -
Antibacterial Agent
Ginkgolic Acid (C13:0) primarily functions as an antibacterial agent and a potent PI3Kδ inhibitor (IC50: 2.49 μM). This compound demonstrates significant antibacterial and anti-parasitic activities, making it valuable in microbiological research. Additionally, Ginkgolic Acid (C13:0) is known to inhibit mast cell degranulation with an IC50 of 2.40 μM, contributing to its potential therapeutic applications in inflammatory conditions. -
Bacterial Inhibitor
3,3'-Di-O-methylellagic acid is a bacterial inhibitor derived from Euphorbia adenochlora. It selectively inhibits the development of acid-fastness in mycobacteria without affecting their growth rates. Additionally, this compound exhibits hepatoprotective properties, likely attributed to its antioxidative effects, making it valuable for research in microbial resistance and liver health. -
SARS-CoV-2 PLpro Inhibitor
Aloin B (Isobarbaloin) is an orally active inhibitor of the SARS-CoV-2 papain-like protease (PLpro), with reported IC50 values of 16.08 μM for hydrolytic activity and 17.51 μM for deubiquitinase activity. This compound demonstrates biological activity in anti-inflammatory pathways and tumor promotion inhibition, making it valuable for research in cancer biology and COVID-19. Additionally, Aloin B is metabolized by intestinal flora to produce aloe-emodin-9-anthrone, which may contribute to its laxative effects. -
Parasite Inhibitor
β-Hederin is a saponin derived from Hedera helix L. (Araliaceae) that demonstrates significant antileishmanial activity. It exhibits IC50 values of 1.5 μM against L. mexicana promastigotes, 68 nM against L. mexicana amastigotes, and 4.57 μM in THP-1 cells. This compound may be utilized in research applications targeting leishmaniasis, providing insights into potential therapeutic strategies against parasitic infections. -
Cholinesterase (ChE) Inhibitor
Corydaline is an isoquinoline alkaloid that functions as a cholinesterase (ChE) inhibitor with an IC50 of 226 μM. In addition to its cholinergic activity, Corydaline acts as a μ-opioid receptor agonist (Ki of 1.23 μM) and demonstrates significant antiviral effects by inhibiting enterovirus 71 (EV71) replication, with an IC50 of 25.23 μM. This compound also exhibits anti-angiogenic, anti-allergic, gastric-emptying, and antinociceptive properties, making it a valuable reagent for various biological research applications. -
HIV Inhibitor
Gomisin G is a lignan derived from Schisandra chinensis that acts as an anti-HIV agent with an EC50 of 0.006 μg/mL. It exhibits anti-liver cancer and anti-inflammatory properties while utilizing an AKT-cyclin D1 dependent mechanism to target triple-negative breast cancer cells by inhibiting phosphorylation rather than promoting apoptosis. Additionally, Gomisin G leads to G1 phase cell cycle arrest and inhibition of AKT phosphorylation. This compound is suitable for research applications focusing on HIV and various cancer types, including breast and liver cancers. -
HIV Protease Inhibitor
Ganoderic acid B is a triterpene derived from the medicinal mushroom Ganoderma lucidum, functioning as an inhibitor of HIV protease. This compound exhibits moderate inhibitory activity against HIV-1 protease, with an IC50 value of 170 μM, making it a potential candidate for research into antiviral therapies. Additionally, ganoderic acid B has demonstrated the ability to inhibit Epstein-Barr virus (EBV) antigen activation and may serve as a telomerase inhibitor, highlighting its broad potential in virology and cancer research applications. -
Bacterial Inhibitor
Methyl Paraben is a bacterial inhibitor primarily used as a preservative in various applications due to its stability and non-volatility. It has been shown to enhance histamine release and modulate cellular immune responses, in addition to blocking sodium channels. Its properties make it valuable for studies exploring microbial inhibition and the mechanisms of ischemia-reperfusion injury. -
Bacterial Biofilm Formation Inhibibitor
D-Phenylalanine is an atypical D-amino acid that functions as a bacterial biofilm formation inhibitor. It integrates into the peptidoglycan layer of bacterial cell walls, particularly replacing D-alanine, which alters cell wall structure and enhances acid resistance, thereby impacting biofilm development. Additionally, D-Phenylalanine may stimulate the secretion of peptide tyrosine tyrosine (PYY) in mammals through activation of the GPR109B receptor, suggesting a role in appetite regulation and blood glucose management. This reagent is valuable for research in antibacterial preservation, probiotic enhancement in the food industry, and metabolic disease studies, including diabetes. -
β-lactam Antibiotic
Dicloxacillin sodium is a β-lactam antibiotic belonging to the penicillin family, specifically designed to combat Gram-positive bacterial infections. It is particularly effective against β-lactamase-producing strains, including Staphylococcus aureus. This compound is widely utilized in research applications focused on antibiotic susceptibility and resistance mechanisms.
