Catalog No.
Product Name
Application
Product Information
Citations
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Penicillium Intermediate
Cyclopeptine is a key intermediate in the biosynthesis of benzodiazepine alkaloids produced by the genus Penicillium. This compound is significant for research into the metabolic pathways of fungal secondary metabolites and their potential applications in pharmacology. Cyclopeptine can also be utilized to study the structural and functional properties of benzodiazepine derivatives in various biological systems. -
Secondary Metabolite of Aspergillus flavus
5,7-Dihydroxy-4-methylphthalide is a secondary metabolite produced by Aspergillus flavus, serving as a crucial intermediate in the synthesis of Mycophenolic acid. This compound exhibits significant biological activity, contributing to the understanding of fungal metabolism and the pharmacological properties of derived compounds. Its applications encompass research into fungal biosynthesis and the exploration of potential therapeutic agents stemming from fungal secondary metabolites. -
Phenolic Compound
3,4,5-Trichloroguaiacol is a phenolic compound primarily targeted for its antibacterial and antifungal properties. It is often utilized in studies examining environmental contaminants, particularly in the context of effluents from bleached kraft pulp mills. This compound serves as an important research tool in understanding the biochemical pathways influenced by chlorinated phenols and their impacts on microbial activity. -
Lanostane-type Triterpenoid Compound
Inonotusane A is a lanostane-type triterpenoid compound isolated from the sclerotia of Inonotus obliquus. This compound exhibits notable biological activity, including potential anticancer properties and immunomodulatory effects. It serves as a valuable reagent for research focused on natural products, herbal medicine, and the therapeutic potential of fungal metabolites in various biological systems. -
Terpenoid
Monardin C is a natural terpenoid known for its ability to modulate various biological pathways. It exhibits significant antibacterial and antifungal activities, making it a valuable compound in microbiological research. Monardin C's unique properties render it useful for studies focused on the therapeutic potential of terpenoids in infectious diseases and alternative medicine approaches. -
Sesquiterpene
10(14)-Cadinene-4,5-diol is a natural sesquiterpene that modulates various biochemical pathways through its interaction with biological targets. Exhibiting antibacterial and antifungal properties, this compound demonstrates significant activity against a range of microbial strains. Its application in research includes the study of plant secondary metabolites and their potential therapeutic uses in combating infections. -
Drug Derivative
Roseofungin is a drug derivative that primarily targets fungal infections by inhibiting fungal cell wall synthesis. Its key biological activity includes antifungal effects against a variety of pathogenic fungi. This compound is valuable in research applications focusing on antifungal drug development and the study of resistance mechanisms in fungal pathogens. -
Sesquiterpene
Phaeocaulisin F is a natural sesquiterpene known for its potential effects on various biological pathways. This compound exhibits significant antibacterial and antifungal activities, making it valuable in research focused on infectious diseases and microbial resistance. Its unique structure and biological properties enable exploration in diverse fields, including pharmacology and natural product chemistry. -
Drug Derivative
Fluopicolide is a novel drug derivative with a primary mechanism targeting specific protein interactions. It exhibits significant antifungal activity, making it suitable for studying plant pathogen resistance and developing effective agricultural fungicides. Fluopicolide is particularly valuable for research applications focused on crop protection and plant disease management strategies. -
Alternaria Metabolite
4-Hydroxyalternariol is a metabolite derived from the fungus Alternaria. It exhibits significant cytotoxic activity and serves as a potent inhibitor of various cell proliferation pathways. This compound is valuable in research focused on mycotoxin studies, apoptosis, and cancer biology, facilitating investigations into the biological effects of fungal metabolites on human health. -
Metabolite
(Z)-2-Octenoic acid is the Z-isomer of 2-Octenoic acid, a significant metabolite derived from Mucor species. It plays a role in various biochemical pathways and can be utilized in studies exploring fungal metabolism and organic compound synthesis. This compound may aid in the investigation of microbial interactions and the functional roles of metabolites in ecological systems. -
Secondary Metabolite
4-Hydroxyscytalone is a microbial secondary metabolite isolated from the oak fungus Diplodia corticola. This compound exhibits toxicity toward Artemia salina with an LC50 value of 90.6 μg/mL, indicating its potential as a bioactive agent. While it does not demonstrate significant antifungal activity, 4-Hydroxyscytalone may serve as a valuable tool in cancer therapy research, facilitating investigations into novel treatment strategies. -
Squalene Synthase Inhibitor
Squalestatin 3 is a potent squalene synthase inhibitor, demonstrating an IC50 of 6 nM. This secondary metabolite, isolated from the fungus Phoma, plays a critical role in regulating the biosynthesis of sterols and terpenes. It is valuable for research applications focused on cholesterol biosynthesis, antifungal research, and the exploration of lipid metabolism pathways. -
Fungal Lactone
Pestalotin is a fungal lactone and a secondary metabolite derived from the endophytic fungus Pestalotiopsis microspora. This compound exhibits significant antifungal activity, making it a valuable tool for research in mycology and natural product chemistry. Its bioactive properties may facilitate the exploration of new antimicrobial agents and contribute to the study of plant-fungal interactions. -
Secondary Metabolite
Fumiquinazoline D is a secondary metabolite that acts as a mycotoxin. It exhibits significant biological activity by inhibiting various cellular processes, potentially impacting cell viability and proliferation. Fumiquinazoline D is utilized in research to study the effects of mycotoxins on human health and to explore its mechanisms of action in fungal biology and toxicity. -
Anticancer Agent/SV40 Promoter Activator
TMC-205 is a natural fungal metabolite that acts as an SV40 promoter activator. It exhibits significant antiproliferative activity against various cancer cell lines, making it a valuable tool for cancer research. This compound is useful for studies on transcriptional regulation and the mechanisms of oncogenesis. -
Antibiotic
Neohydroxyaspergillic acid is an antibiotic that exhibits activity against specific bacteriophages. This compound can be utilized in research focusing on antibacterial mechanisms and the interaction between antibiotics and bacteriophages. Its potential applications extend to studying resistance and susceptibility patterns in microbial populations. -
Bacterial Metabolite
Corynecin IV is a chloramphenicol-like bacterial metabolite that targets bacterial protein synthesis through inhibition of the bacterial ribosome. This compound exhibits antimicrobial activity against a range of Gram-positive bacteria, making it valuable for research in antibiotic development and resistance studies. Additionally, Corynecin IV can be utilized to explore mechanisms of action for similar anti-infective agents. -
Fungi Metabolites
Scytalone is a naphthalenone pentaketide that serves as a natural precursor to melanin. This compound is derived from certain tracheiphilous fungi and is relevant in the study of fungal metabolites. Research indicates that scytalone may play a role in grape esca disease, making it a valuable reagent for investigations into plant pathology and fungal biology. -
Ciosynthetic Precursor of Satratoxin G
Roridin L2 is a fungal metabolite that serves as a biosynthetic precursor to Satratoxin G. This compound plays a crucial role in the synthesis of Satratoxin G, which is known for its potential biological activities. Despite its significance in research applications, Roridin L2 exhibits minimal toxic activity both in vitro and in vivo, making it a valuable reagent for studying fungal metabolites and their derivatives. -
Bacterial Metabolite
4-Hydroxycinnamide is a bacterial metabolite derived from Streptomyces sp. PU-KB10-4. This compound exhibits significant biological activity, making it a valuable tool in microbial research. Its role in bacterial metabolism may provide insights into host-microbe interactions and potential therapeutic applications. -
Metabolite
Eremofortin A is a natural metabolite derived from the fungus Penicillium roqueforti. This compound exhibits a range of biological activities, including potential antifungal and cytotoxic effects. Eremofortin A is primarily utilized in research applications focused on exploring fungal metabolites and their therapeutic potentials in the treatment of various diseases. -
Acinar Morphogenesis Inhibitor
Fusarisetin A is a pentacyclic fungal metabolite that functions as an acinar morphogenesis inhibitor. This compound disrupts the normal formation and development of acinar structures in cells, making it a valuable tool for investigating the mechanisms of acinar morphogenesis. Its unique biological activity supports research in developmental biology and tissue engineering. -
C-14 Epimer
14-epi-Berkeleylactone F is a C-14 epimer of Berkeleylactone F, isolated from the fungus Penicillium turbatum NRRL 5630. While it demonstrates structural similarity to its counterpart, 14-epi-Berkeleylactone F exhibits no significant biological activity against a range of pathogens, including Staphylococcus aureus, Bacillus subtilis, E. coli, Candida albicans, and the parasite Giardia duodenalis, as well as NS-1 murine myeloma cells. This compound may be relevant for studies focusing on epimerization and structural analysis in fungal metabolites. -
Secondary Metabolite
Neosartoricin D is a polyketide and a microbial secondary metabolite isolated from the culture of Aspergillus nidulans. This compound exhibits biological activity that suggests potential immunomodulatory effects, influencing host-pathogen interactions during fungal infections. Neosartoricin D serves as a valuable research tool for studying the mechanisms of fungal pathology and its impact on host immune responses. -
Succinate Dehydrogenase Inhibitor
Flubeneteram is an inhibitor of succinate dehydrogenase, exhibiting an IC50 value of 0.0484 μM. This compound effectively disrupts the activity of succinate dehydrogenase, contributing to its biological activity. Flubeneteram has demonstrated protective effects against fungal pathogens such as Rhizoctonia solani and Sphaerotheca fuliginea in preclinical studies. It is a valuable reagent for research focused on fungal infection mechanisms and potential therapeutic strategies. -
PPT1 Inhibitor
Ezurpimtrostat (hydrochloride) is a potent and selective PPT1 inhibitor with multiple biological activities. It disrupts lysosomal function, modulates autophagy, and induces apoptosis, making it a valuable tool in cancer research and immunology. This compound has demonstrated efficacy in reducing inflammatory markers such as IFN-α and CRP, as well as in lowering viral loads of SARS-CoV-2. Ezurpimtrostat is suitable for investigating conditions such as systemic lupus erythematosus, hepatocellular carcinoma, fibrosis, and other related disorders. -
Immunosuppressant
Homodestcardin is a destruxin-based cyclodepsipeptide that functions as an immunosuppressant. Derived from fungal sources, it exhibits significant inhibitory activity against concanavalin A (Con A) activation, demonstrating an IC50 value of 0.86 μM. This compound is of interest for research applications focused on immune modulation and the study of autoimmune disorders. -
Biologically Active Metabolite
Varioxepine A is a 3H-oxepine-containing alkaloid that acts as a biologically active metabolite derived from the marine algal endophytic fungus Paecilomyces variotii. This compound exhibits inhibitory activity against the plant pathogenic fungus Fusarium graminearum, making it a valuable tool for research in phytopathology and the study of plant-fungal interactions. Its unique structural features may also provide insights into the development of novel antifungal agents. -
Surface Glycans of EVs
6′SLN is a sialic acid derivative that targets surface glycans of extracellular vesicles (EVs). It plays a crucial role in protein glycosylation within EVs and is known to interact with hemagglutinins from both human and avian influenza virus strains. Research applications include the investigation of anti-influenza drug mechanisms and the study of EV-mediated communication in cancer biology. -
Mitochondrial Inhibitor
Fusaramin is a mitochondrial inhibitor that demonstrates potent activity against plant pathogenic fungi. It disrupts mitochondrial function, leading to the impairment of fungal growth and viability. This compound is valuable for research applications focused on plant disease management and the study of mitochondrial biology in pathogenic organisms. -
SDH Inhibitor
Inpyrfluxam is a potent inhibitor of succinate dehydrogenase (SDH), specifically targeting the ubiquinone binding pocket of the mitochondrial SDH complex subunits ViSDHB, ViSDHC, and ViSDHD. This inhibition disrupts cellular respiration, demonstrating efficacy in inhibiting conidial germination and mycelial growth of Venturia inaequalis in vitro. Inpyrfluxam is valuable for research studies focused on apple scab and related fungal pathogens. -
HIV-1 Integrase Inhibitor
GSK-1264 is an HIV-1 integrase inhibitor that targets the catalytic core and C-terminal domains of the HIV-1 integrase enzyme. By promoting the formation of an open polymer structure of integrase dimers, GSK-1264 disrupts the late stages of HIV replication and interferes with viral particle assembly. This compound is valuable for research focused on HIV infection and understanding integrase-mediated processes in the viral life cycle. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 8 is a selective inhibitor targeting the HIV-1 integrase enzyme. It demonstrates potent activity against viral replication by disrupting the integration of viral DNA into the host genome, which is essential for the HIV life cycle. This compound is primarily utilized in research focused on antiretroviral therapy and the development of HIV treatments, contributing to the understanding of integrase inhibition mechanisms. -
HIV-1Integrase Inhibitor
GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase, targeting the enzyme responsible for the integration of viral DNA into the host genome. This compound exhibits significant antiviral activity against HIV-1, making it a valuable tool for research applications focused on the development of novel antiretroviral therapies and the study of HIV replication mechanisms. Its unique mechanism of action may provide insights into resistance pathways and inform drug design strategies. -
HIV Integrase Inhibitor
His-Cys-Lys-Phe-Trp-Trp is an HIV integrase inhibitor, exhibiting an IC50 of 2 μM. This compound impedes the integrase enzyme's function, thereby preventing viral DNA integration into the host genome. His-Cys-Lys-Phe-Trp-Trp is valuable for research focused on HIV pathogenesis and the development of antiretroviral therapies. -
HIV-1 integrase Inhibitor
(S)-BI-1001 is a potent HIV-1 integrase inhibitor, demonstrating significant antiviral activity. It exhibits an IC50 value of 28 nM, an EC50 of 450 nM, and a Kd of 4.7 μM, indicating its efficacy in disrupting viral replication processes. This compound is valuable for research applications focused on HIV-1 pathogenesis and therapeutic development. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 7 is a potent inhibitor of HIV-1 integrase, exhibiting an IC50 value of 33.3 nM. This compound effectively interferes with the integration of viral DNA into the host genome, making it essential for studies focused on HIV-1 replication and treatment strategies. It serves as a valuable tool in research applications aimed at understanding HIV-1 biology and developing therapeutic interventions against HIV. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 11 is a potent inhibitor of HIV-1 integrase, demonstrating an IC50 of 125 μM. This compound effectively disrupts the integration of viral DNA into the host genome, thereby hindering the replication process of HIV-1. It is suitable for research applications aimed at developing antiretroviral therapies and studying the mechanisms of HIV integration and resistance. -
HIV-1 IN/RT RNase H Inhibitor
2-Hydroxyisoquinoline-1,3(2H,4H)-dione is an inhibitor of HIV-1 integrase (IN) and reverse transcriptase (RT) ribonuclease H (RNase H), demonstrating IC50 values of 6.32 µM and 5.9 µM, respectively. This compound serves as a valuable tool for studying HIV-1 replication and provides insights into the inhibition mechanisms of viral enzymes. Its biological activity and specificity make it useful for research applications focused on antiviral drug development and understanding HIV-1 pathogenesis. -
HIV Integrase Inhibitor
L-870812 is an HIV integrase inhibitor that targets the strand transfer mechanism of HIV-1 integration. This compound effectively blocks both cell-free and cell-associated HIV-1 infections, demonstrating activity against subtype C and CRFO2_AG primary isolates. L-870812 is suitable for research applications involving replication-deficient HIV-1 Ba-L (env) pseudovirus, facilitating studies aimed at understanding HIV biology and developing therapeutic strategies. -
Anti-bacterial Agent
6-Bromocoumarin is a potential anti-bacterial agent that demonstrates selective binding affinity for α and β estrogen receptors. While it does not inhibit 17β-HSD1, its unique properties make it a valuable compound for researchers studying bacterial resistance mechanisms and the role of estrogen receptors in microbial pathogenesis. 6-Bromocoumarin may provide insights into the development of novel anti-bacterial therapies targeting hormonal pathways. -
Acyltransferase Inhibitor
Amidepsine A is an acyltransferase inhibitor derived from the fungal metabolite of Humicola sp. FO-2942. This compound specifically inhibits the activity of diacylglycerol acyltransferases (DGAT), which play a crucial role in lipid metabolism. Its biological activity makes Amidepsine A a valuable reagent for research applications focused on lipid biosynthesis and metabolic regulation. -
Stable Isotope
Loratadine-d5-1 is a deuterated analog of Loratadine, which serves as a selective inverse agonist of peripheral histamine H1 receptors. It exhibits an IC50 of greater than 32 μM and has been shown to possess anti-dengue virus (DENV) activity. Additionally, Loratadine is capable of inhibiting the immunologic release of inflammatory mediators, making it a valuable tool for research in allergy and inflammation studies. -
Antimicrobial Agent
1,2-Hexanediol serves as a broad-spectrum antimicrobial agent with significant antibacterial and antifungal properties. It exhibits bactericidal activity against both Gram-positive and Gram-negative bacteria, while also effectively inhibiting various fungal organisms. The compound disrupts the cytoplasmic membrane potential of bacteria, making it an essential tool in research focused on bacterial and fungal infections, as well as applications in cosmetic preservation. -
Fungicide
Nuarimol is a fungicide that primarily targets fungal pathogens to protect crops in agricultural applications. This compound functions as a phenobarbital-type inducer of hepatic drug-metabolizing enzymes, leading to transient, significant hepatic regenerative proliferation and accompanying hepatomegaly through reversible hepatocellular injury. Research indicates its potential utility in studies exploring liver regeneration and metabolic enzyme regulation. -
Isomer
(E/Z)-Diniconazole is an isomer of the well-studied fungicide Diniconazole, primarily targeting plant fungal pathogens. Its biological activity includes the inhibition of specific fungal processes, making it valuable for research focused on the control of plant fungal diseases. Additionally, it plays a role in studies regarding plant growth regulation, offering insights into its effects on agricultural practices and crop management. -
Drug Isomer
rel-Hydroxy Itraconazole is a relative stereoisomer of Hydroxy Itraconazole, which serves as the primary active metabolite of the antifungal agent Itraconazole. This compound exhibits significant antifungal activity and is crucial in studying the pharmacological effects of its parent drug. It is primarily utilized in research applications focused on antifungal mechanisms and drug metabolism. -
Angucycline Antibiotic
Urdamycin A is an angucycline antibiotic derived from Streptomyces fradiae. Notably, it functions as an orange pH indicator, shifting to ultramarine blue at pH 7.7. Urdamycin A exhibits significant anticancer activity, showing IC50 values of 2.4 μg/mL in proliferation assays and 0.55 μg/mL in stem cell assays. This compound is relevant for research applications in cancer biology and antibiotic activity studies. -
Azasterol
Fluoro azasterol is an azasterol derivative that functions as a potent inhibitor of parasitic and fungal growth. This compound exhibits significant biological activity against various pathogens, making it a valuable tool for research in the fields of parasitology and mycology. Its applications include studying the mechanisms of anti-parasitic and antifungal action, as well as exploring potential therapeutic uses in infectious disease models.
