Catalog No.
Product Name
Application
Product Information
Citations
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Antifungal Agent
Toonaciliatin M is a pmaradiene-type diterpenoid derived from Toona ciliate, exhibiting potent antifungal activity primarily against Trichophyton rubrum. With a minimum inhibitory concentration (MIC) of 12.5 µg/mL, it is a valuable compound for investigating antifungal mechanisms and exploring potential therapeutic applications in fungal infections. Researchers can utilize Toonaciliatin M to better understand its efficacy and broader applications in antifungal drug development. -
Chitin Deacetylase Inhibitor
CDA-IN-2 is a potent inhibitor of chitin deacetylase (CDA), effectively targeting the enzymes PxCDA1 and PxCDA2 in the pathogen P. xanthii. At a concentration of 100 μM, CDA-IN-2 demonstrates significant antifungal activity, achieving inhibition rates of 83.7% and 74.5%, respectively. This compound is valuable for research into managing agricultural fungal diseases, particularly against resistant strains of powdery mildew and Botrytis cinerea. -
Antifungal Agent
Sulconazole is a potent antifungal agent belonging to the imidazole class, primarily known for its ability to inhibit fungal growth. It exerts its effects by blocking the NF-κB/IL-8 signaling pathway, which is implicated in cancer stem cell formation and tumor progression. Additionally, Sulconazole shows potential for applications in breast cancer research, highlighting its dual role as both an antifungal and an anti-tumor compound. -
Fungicide
Zarilamid is a fungicide targeting Oomycete fungi, demonstrated to inhibit nuclear division in germinating zoospore cysts of Phytophthora capsici. This compound disrupts microtubule cytoskeleton integrity, leading to impaired mitosis and abnormal swelling of root tips in tobacco. Zarilamid is valuable for research on fungal growth inhibition and cellular mechanisms associated with Oomycete pathogens. -
Fungal
Phlebiakauranol aldehyde is a potent antifungal and cytotoxic metabolite, primarily targeting fungal pathogens. It demonstrates significant antibacterial and cytotoxic effects against various plant pathogens, attributed to its aldehyde group and multiple hydroxyl groups. This compound serves as a valuable tool for research in fungal biology and antimicrobial activity, providing insight into its mechanisms of action and potential applications in plant protection. The related acetic acid derivatives exhibit only minimal biological activities, highlighting the unique efficacy of Phlebiakauranol aldehyde. -
1,3-β-glucan Synthase Inhibitor
Arborcandin D is a potent inhibitor of 1,3-β-glucan synthase, functioning as an effective antifungal antibiotic. It demonstrates notable inhibitory activity with IC50 values of 3 μg/mL against Candida albicans and 0.35 μg/mL against Aspergillus fumigatus. Furthermore, Arborcandin D exhibits a minimal inhibitory concentration (MIC) of 4 μg/mL against the Candida genus, making it a valuable tool for research on fungal infections and treatment development. -
Antifungal Agent
Sporothriolide, a potent antifungal agent derived from the metabolite of Nodulisporium sp. A21, exhibits strong inhibitory effects against various fungal pathogens, specifically R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Additionally, Sporothriolide effectively inhibits the conidium germination of Magnaporthe oryzae, both in vitro and in vivo, making it a valuable tool for research in antifungal activity and plant disease management. -
Antifungal Agent
13-Epimanool is a potent antifungal agent derived from the bark of the Taiwan hemlock. This compound exhibits significant inhibitory activity against various fungal pathogens, making it a valuable tool for research into antifungal treatments and mechanisms. Its unique properties facilitate investigations into the biosynthetic pathways of natural products and the development of novel antifungal therapies. -
Secondary Metabolite
Strevertene A is a pentaene macrolide classified as a secondary metabolite with notable antibiotic properties. This compound exhibits potent antifungal activity, effectively inhibiting the mycelial growth of various phytopathogenic fungi, including Alternaria mali, Aspergillus oryzae, and Cylindrocarpon destructans, with IC50 values ranging from 4 to 16 μg/mL. Additionally, Strevertene A demonstrates the ability to significantly mitigate the development of Fusarium wilt in tomato plants, making it a valuable reagent for agricultural and fungal research applications. -
Antibiotic
Funiculosin is a neutral lipophilic antibiotic that primarily targets DNA and RNA viruses, demonstrating significant antiviral activity. Additionally, it exhibits antifungal properties, effectively inhibiting infections caused by pathogenic fungi in primary chicken embryo fibroblasts. This compound is valuable for research in virology and mycology, providing insight into viral and fungal pathogenesis and potential therapeutic strategies. -
Fungal Inhibitor
Antifungal agent 20 is a potent fungal inhibitor that demonstrates significant antifungal activity against a range of pathogens, including Colletotrichum gloeosporioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum. This compound is utilized in research applications focusing on fungal diseases, providing a valuable tool for studying plant pathology and developing effective control measures. -
Anti-Fungal Agent
Fusacandin A is an antifungal agent that targets (1,3)-β-glucan synthetase, an enzyme critical for fungal cell wall synthesis. By inhibiting this enzyme, Fusacandin A effectively disrupts fungal growth and division. This compound is useful in research applications focused on antifungal drug development and the investigation of fungal cell wall integrity. -
Antifungal Agent
Amorolfine is an antifungal agent that targets the biosynthesis of ergosterol. It effectively combats onychomycosis by inhibiting fungal growth, particularly against Candida albicans, exhibiting a minimum inhibitory concentration (MIC) of 0.404 µg/mL. This compound is valuable in research applications focused on antifungal mechanisms and the treatment of fungal infections. -
Fungal Inhibitor
Apigeninidin chloride is a 3-deoxyanthocyanidin that serves as a potent fungal growth inhibitor. Its unique structure imparts bioactive properties, making it useful as a red biocolorant in various applications. This compound is valuable for studying fungal biology and exploring potential antifungal strategies in research settings. -
1,3-β-glucan Synthase Inhibitor
Arborcandin E is a potent inhibitor of 1,3-β-glucan synthase, functioning as an effective antifungal antibiotic. It demonstrates remarkable inhibitory activity with IC50 values of 0.1 μg/mL for Candida albicans and 0.012 μg/mL for Aspergillus fumigatus. Arborcandin E also shows a minimum inhibitory concentration (MIC) range of 0.5-2 μg/mL against various Candida species, making it a valuable tool for studying fungal infections and potential therapeutic applications. -
Anti-Fungal Agent
S-F24 is an antifungal agent that targets CYP3A4, exhibiting an IC50 value of 0.4 μM. It demonstrates broad-spectrum antifungal activity with a favorable safety profile, including high selectivity, minimal hemolytic effects, and a low propensity for resistance development. S-F24 is suitable for research into fungal infections and may aid in the exploration of potential therapeutic strategies. -
Fungal Inhibitor
Isohemigossylic acid lactone 2-methyl ether is a sesquiterpene lactone that acts as a fungal inhibitor, specifically targeting Verticillium dahliae. It demonstrates significant antifungal activity, inhibiting conidial growth with an ED50 of 7.8 μg/mL. Sourced from the roots of Bombax malbaricum, this compound is particularly useful for research applications focused on Verticillium dahliae infections and related fungal pathogenicity studies. -
Antifungal Agent
Antifungal Agent 22 (compound D16) is an orally active antifungal agent targeting cryptococcal meningitis, exhibiting a potent IC50 of 0.5 μg/mL. This compound effectively penetrates the blood-brain barrier and exerts its antifungal activity by compromising the integrity of fungal cell membranes in Cryptococcus neoformans H99. Antifungal Agent 22 demonstrates selective anti-Cryptococcus efficacy, characterized by good metabolic stability and low cytotoxicity, making it a promising candidate for therapeutic applications in fungal infections. -
Antifungal Agent
Senkyunolide B is a naturally occurring phthalide derived from Angelica sinensis, exhibiting potent antifungal activity. It effectively inhibits the spore germination and hyphal growth of Aspergillus fumigatus by down-regulating the phosphatidylinositol-PKC-calcineurin signaling pathway and the expression of ENG genes. This compound is a valuable tool for research in antifungal drug development and pathogenic fungal biology. -
1,3-β-glucan Synthase Inhibitor
Arborcandin B is a potent inhibitor of 1,3-β-glucan synthase, functioning as an antifungal agent. It demonstrates notable biological activity with IC50 values of 0.30 μg/mL against Candida albicans and 0.025 μg/mL against Aspergillus fumigatus. Arborcandin B also reveals a minimum inhibitory concentration (MIC) of 2-4 μg/mL against various species within the genus Candida, making it a valuable tool for research in antifungal mechanisms and therapies. -
Pdr5p Inhibitor
Norbatzelladine L is a selective inhibitor of the Pdr5p transporter, demonstrating significant inhibition of its catalytic and functional activities. With an IC50 of 3.8 µM, Norbatzelladine L effectively suppresses Pdr5p ATPase activity. This compound exhibits a broad spectrum of biological activities, including antifungal, antiparasitic, antiviral, antibacterial, and antitumoral effects, making it a valuable tool for diverse research applications in microbiology and cancer studies. -
Antibiotic
Leucinostatin K is a peptide antibiotic that targets and inhibits the growth of gram-positive bacteria and fungi. Isolated from Paecilomyces lilacinus, it exhibits significant antibacterial and antifungal properties, making it a valuable tool for studying microbial infections and resistance mechanisms. Its unique mechanism of action offers insights into potential therapeutic applications in treating bacterial and fungal diseases. -
Antifungal Agent
Leotiomycene C is an isoprenylated bisresorcinol derivative derived from the freshwater fungus Helotiales sp., functioning primarily as an antifungal agent. This compound effectively disrupts the quorum sensing mechanisms of methicillin-resistant Staphylococcus aureus (MRSA), exhibiting an IC₅₀ value between 6.3 and 12.5 μM. Leotiomycene C is relevant for research focused on combating MRSA infections and understanding quorum sensing pathways in pathogenic bacteria. -
Antifungal Agent
2,5-Dimethylhexane-3,4-diol is an antifungal agent with demonstrated in vitro efficacy against various fungal pathogens. This compound, derived from Mansoa hirsuta, serves as a valuable tool for research into the mechanisms of fungal infections and potential treatments. Its biological activity makes it suitable for studies focused on antifungal drug development and resistance. -
Antifungal Agent
Antifungal Agent 54 is a potent antifungal compound that targets resistant strains of Candida albicans, exhibiting superior efficacy compared to traditional antifungal drugs. With minimal inhibitory concentration (MIC) values ranging from 0.25 to 1 μg/mL, it demonstrates significant activity against Fluconazole-resistant strains. This reagent is suitable for research applications focused on tackling antifungal resistance and evaluating new therapeutic options for fungal infections. -
Fungal Inhibitor
Hexamide is a potent fungal inhibitor primarily targeting Trichophyton species. Its efficacy makes it a valuable compound for studying fungal infections and evaluating antifungal therapies. This reagent can be utilized in various research applications involving mycology and the development of antifungal agents. -
Antifungal/Antibacterial Agent
2-Deethoxy-2-hydroxyphantomolin is a germacranolide known for its antifungal and antibacterial properties. Isolated from the whole plant of Elephantopus tomentosus and leaves of E. mollis, it exhibits moderate activity against Candida albicans, with a clearing zone of 14 mm, and slight activity against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis (12-14 mm clearing zones). Additionally, it shows some efficacy against Trichophyton mentagrophytes, making it a compound of interest for research in microbial infections. -
Microbial Antagonist
3-Methyl-1-hexanol is a microbial antagonist with antifungal properties, derived from the fungus Aureobasidium pullulans. This volatile organic compound exhibits effective inhibitory activity against pathogens such as Alternaria alternate and Botrytis cinerea. It serves as a valuable tool for research focused on microbial infections and fungal disease management. -
Fungal Inhibitor
Aleurodiscal is a fungal inhibitor derived from Aleurodiscus mirabilis. It demonstrates significant antifungal activity, making it a valuable tool in the study of fungal infections. This compound can be utilized in research applications focused on understanding fungal pathogenesis and developing antifungal therapies. -
Antioxidant Compound
Sclerotioramine, an antioxidant compound, is derived from the endolichenic fungus Penicillium sp.-strain 1322P. This compound demonstrates strong antibacterial activity, with minimum inhibitory concentrations (MICs) of 3.125 μg/mL against Bacillus subtilis and Bacillus megaterium, and 6.25 μg/mL against Shigella dysentery. In addition, sclerotioramine exhibits considerable antifungal efficacy against various pathogens, including Pestalotiopsis theae, Cochliobolus miyabeanus, and Exserohilum turcicum, making it a valuable reagent for research in microbiology and antimicrobial studies. -
Fungal Inhibitor
Stilbamidine is a diamidine compound that targets fungal infections by inhibiting fungal growth. Primarily utilized in its crystalline isethionate salt form, this reagent is effective against a range of fungi, making it valuable for research applications involving fungal pathology and treatment mechanisms. Its biochemical properties support studies focused on antifungal activity and resistance mechanisms in various fungal species. -
Antitubercular Agent
Antituberculosis agent-8 is a potent antitubercular compound exhibiting a minimum inhibitory concentration (MIC) of 3.53 μM (1.6 μg/mL) against Mycobacterium tuberculosis H37Rv. In addition to its significant antibacterial properties, this compound demonstrates notable antifungal activity against Aspergillus niger, with an MIC of 62.50 μM. It serves as a valuable tool for research in tuberculosis and antifungal studies, aiding in the development of therapeutic strategies for these infections. -
Antibacterial/Fungicidal Agent
Sepiumol A is a polyphenolic compound derived from the bark of Periploca sepium Bunge, functioning as an antibacterial and antifungal agent. This compound demonstrates notable biological activity against various bacterial and fungal strains, making it a valuable resource in microbiological research. Additionally, Sepiumol A has potential applications in the formulation of e-cigarette liquids, where it may help mitigate undesirable sweetness and greasiness while enhancing microbial safety. -
Antifungal Agent
Oosponol is a potent inhibitor of dopamine beta-hydroxylase, known for its hypotensive properties. In addition to its cardiovascular effects, Oosponol displays significant antifungal activity against a wide range of pathogenic fungi. It serves as a valuable reagent for research in antifungal drug discovery and the study of fungal pathogenesis. -
Antifungal Agent
Oxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research. -
Fungicide
Pencycuron is a benzoylurea fungicide that acts by inhibiting the synthesis of fungal cell walls. It exhibits effective antifungal activity against a range of pathogens, including those responsible for sheath blight, powdery mildew, and late blight in crops. Pencycuron is a valuable reagent for research focused on developing strategies for managing fungal diseases in agricultural settings. -
Antibiotic
Reductiomycin is an antibiotic that primarily targets gram-positive bacteria and fungi. It demonstrates significant antimicrobial activity, making it effective in combating various infections. Additionally, Reductiomycin has been shown to exhibit antitumor properties, supporting its potential use in cancer research. -
SDH Inhibitor
SDH-IN-25 is a selective inhibitor of succinate dehydrogenase (SDH), with an IC50 value of 4.82 mg/L. This compound displays significant antifungal activity by disrupting respiratory metabolism through its binding to complex II, consequently inducing hyphal morphology changes, generating reactive oxygen species (ROS), and affecting mitochondrial membrane potential (MMP) in fungal mycelia. SDH-IN-25 is suitable for research applications focused on agricultural disease management and the development of novel antifungal strategies. -
Tunicamycin Derivative
Tunicamycin B is a derivative of Tunicamycin known for its antimicrobial properties. It demonstrates significant antibacterial activity against Bacillus thuringiensis strains BT01 and W102, with minimum inhibitory concentrations (MICs) of 0.125 and 0.063 μg/mL, respectively. Additionally, it exhibits antifungal activity against Candida albicans strains ATCC 96901 and CMCC (F) 98001, with MICs of 8.0 and 4.0 μg/mL, respectively. Tunicamycin B is suitable for research applications focused on antimicrobial mechanisms and efficacy. -
Quinine Derivative
Quininone is a quinine derivative that targets various fungal pathogens, exhibiting notable in vitro antifungal activity. This compound is instrumental in antifungal research, facilitating the exploration of novel therapeutic strategies against fungal infections. Its unique chemical properties make it a valuable reagent for scientists investigating the mechanisms of antifungal action and resistance. -
Drug Derivative
Procyanidin A3 is a polyphenolic compound belonging to the proanthocyanidin subclass, characterized by its electrophilic flavanyl unit. This reagent exhibits significant antioxidant and anti-cancer activities and demonstrates anti-inflammatory, cardioprotective, antibacterial, and antifungal properties. Procyanidin A3 is utilized in research applications related to chronic venous insufficiency, capillary fragility, sunburn, and retinopathy, making it a valuable tool for studying its therapeutic potential in various diseases. -
Fungal
PF-184563 is a fungal metabolite derived from the tremorigen-producing fungus Penicillium. This compound exhibits significant neurotoxic properties and is proposed as a potential causative agent of ryegrass spurt disease. PF-184563 serves as an important tool for studying fungal neurotoxicity and its implications in agricultural settings. -
Antibiotic
Antibiotic PF 1052 is a natural-derived antibiotic that targets the modulation of immune cell function. It exhibits a significant inhibitory effect on murine neutrophil migration, making it a valuable reagent for studies in immunology and inflammation. Its unique mechanism of action provides insights into the regulation of neutrophil activity and can aid in the investigation of therapeutic strategies for inflammatory diseases. -
Antifungal Agent
Cascaroside B is a flavonoid known for its antifungal properties, derived from the bacterium Pseudomonas aeruginosa Ld-08. This compound exhibits significant activity against various fungal strains, making it a valuable reagent for studying antifungal mechanisms and developing therapeutic agents. Its application in research can contribute to the understanding of fungal resistance and identification of potential treatment strategies. -
Fungal Inhibitor
Fungicide5 is a potent fungal inhibitor that specifically targets succinate dehydrogenase, exhibiting an inhibitory constant (Ki) of 0.095 μM. This compound is designed for research applications in evaluating antifungal properties and exploring metabolic pathways in fungi. Its selective action makes it a valuable tool for studying fungal biology and developing antifungal strategies. -
Antifungal Agent
Stemphyperylenol is a potent antifungal agent primarily targeting the plant pathogen Alternaria solani, demonstrating an impressive minimum inhibitory concentration (MIC) of 1.57 μM. This compound is useful in studying fungal resistance mechanisms and developing antifungal strategies in agricultural research. Its effectiveness against key plant pathogens highlights its potential for protecting crops from fungal infections. -
Antifungal/Anticancer Agent
Globosuxanthone A is a dihydroxanthenone that exhibits significant antifungal activity against Fusarium graminearum, Fusarium solani, and Botrytis cinerea, displaying minimum inhibitory concentration (MIC) values of 4, 8, and 16 μg/mL, respectively. Additionally, it demonstrates potential anticancer properties, making it a valuable tool for research in both mycology and oncology. This compound can be utilized in studies aimed at developing new antifungal therapies as well as anticancer agents. -
Nucleoside Antibiotic
Herbicidin A is an adenosine-derived nucleoside antibiotic that selectively targets dicotyledonous plants, acting as an effective herbicide. This compound is isolated from the bacterial species Streptomyces scopuliridis M40. It holds potential applications in agricultural research and investigation of nucleoside analogs in pharmacological settings. -
Antifungal Agent
Aminocandin is a water-soluble antifungal agent belonging to the echinocandin class, primarily targeting fungal cell wall synthesis. It demonstrates significant potency against Aspergillus and Candida species, making it a valuable tool for studying antifungal mechanisms and treatments. Its effective inhibition of fungal growth supports research in clinical microbiology and therapeutic development. -
Antibacterial/Antifungal Agent
Sporminarin B is an antibacterial and antifungal agent known for its inhibitory effects on various microorganisms, including Candida albicans and Staphylococcus aureus. It is a valuable candidate for research applications aimed at understanding microbial resistance and developing new therapeutic strategies against bacterial and fungal infections.
