Catalog No.
Product Name
Application
Product Information
Citations
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Antimicrobial Agent
Dihydroniphimycin is an antimicrobial agent with potent activity against fungi, yeasts, and Gram-positive bacteria. This compound is utilized in research exploring mechanisms of antifungal resistance and the development of new antimicrobial therapies, making it valuable for studies aimed at addressing infections caused by resistant microbial strains. -
Antibiotic, PKC Inhibitor
RK-286D is a potent antibiotic and selective protein kinase C (PKC) inhibitor that exhibits significant antimicrobial properties. This compound effectively inhibits bleb formation induced by phorbol 12,13-dibutyrate (PDBu) and demonstrates notable activity in vitro against PKC. RK-286D is suitable for research applications exploring microbial resistance and PKC-related cellular signaling pathways. -
Antifungal Agent, Anti-cancer Agent
Shizukanolide F is a dimeric sesquiterpene derived from Chloranthus japonicus Sieb. It demonstrates significant antifungal activity against various plant pathogenic fungi, making it a valuable reagent in agricultural research. Additionally, Shizukanolide F has shown potential anti-cancer properties, particularly in inhibiting metastasis in breast cancer, supporting its application in cancer research studies. -
Antifungal Agent
Agrocybin is an antifungal peptide targeting various fungal species, exhibiting potent antifungal activity without affecting bacterial growth. Additionally, Agrocybin has been shown to inhibit the activity of HIV-1 reverse transcriptase. This compound is valuable for research applications in studying antifungal mechanisms and the interactions between fungal pathogens and antiviral treatments. -
Fungal Inhibitor
Benz[g]isoquinoline-5,10-dione is a potent fungal inhibitor derived from the ethanolic extract of Mitracarpus scaber. It exhibits significant in vitro activity against various pathogens associated with AIDS, as well as notable antibacterial and antifungal effects demonstrated through agar well-diffusion assays. This compound is valuable for research applications focused on antimicrobial activity and the development of therapeutic strategies against opportunistic infections. -
Anti-Fungal Agent
Mathemycin A is an antifungal agent that exhibits potent inhibitory effects against pathogenic fungi. It effectively inhibits the growth of Phytophthora infestans JO8 in vitro, with a minimum inhibitory concentration (MIC) of 7.8 μg/mL. In greenhouse studies, Mathemycin A demonstrates an LD50 of 42 × 10^-6 and an LC90 of 500 × 10^-6, highlighting its potential utility in agricultural research and disease management applications. -
Antibiotic
Melithiazole A is an antibiotic that functions as a β-methoxyacrylate inhibitor, exhibiting strong antimicrobial activity. It demonstrates notable antifungal properties and shows cytotoxic effects, making it valuable for research applications related to infectious diseases and cancer biology. Its unique mechanism of action contributes to the exploration of novel therapeutic strategies in the realm of antibiotic research. -
Anti-Fungal Agent
Clavamycin D is a potent anti-fungal agent known for its strong activity against Candida species. Its efficacy can be antagonized by di- and tripeptides, while amino acids do not affect its action. Clavamycin D does not exhibit antibacterial properties and does not inhibit β-lactamase enzymes, making it a specific choice for antifungal research applications. -
Sesquiterpenoid Phytoalexin
Isolubimin is a sesquiterpenoid phytoalexin derived from Datura stramonium, exhibiting notable antibacterial properties. This compound plays a critical role in plant defense mechanisms and is a valuable asset in research focused on combating fungal infections and understanding plant disease responses. Its potential applications extend to studies on plant-pathogen interactions and the development of natural antibacterial agents. -
Prp8 intein Inhibitor
Antifungal agent 151 is a selective inhibitor of the Prp8 intein, targeting its self-splicing mechanism and disrupting the maturation of the Prp8 protein. This compound demonstrates significant in vitro antifungal activity against Cryptococcus neoformans and Cryptococcus gattii. Antifungal agent 151 is valuable for research applications focused on cryptococcal pneumonia and related fungal infections. -
Antifungal Agent
Sclerodione is a metabolite derived from the Scleroderris canker fungus, Gremmeniella abietina, exhibiting potent antifungal properties. This compound functions as a lipase inhibitor, demonstrating a half-maximal inhibitory concentration (IC50) of 1 μM. Sclerodione is valuable for research applications focused on fungal pathogenesis and the study of enzyme inhibition mechanisms. -
Pentanorlanostane Derivative
Cladosporide D is a pentanorlanostane derivative, isolated from the strain of Cladosporium sp. IFM 49191. While it lacks antifungal activity, Cladosporide D serves as an important compound for research in the exploration of natural products and their derivatives. Its unique structure may facilitate studies in biochemistry and pharmacology related to sterol biosynthesis pathways. -
Antibiotic
Papulacandin D is an antibiotic targeting yeast pathogens. It exhibits potent anti-yeast activity, effectively inhibiting their growth while showing no efficacy against filamentous fungi, bacteria, or protozoa. This compound is useful in research applications focusing on fungal infections and yeast-related studies. -
Fungicide
Furalaxyl is a potent fungicide targeting fungi within the order Peronosporales. Its high selectivity towards these pathogens makes it an effective choice for managing various fungal diseases in agricultural applications. Furalaxyl inhibits fungal growth, offering a targeted approach to disease control and improving crop health. -
Antifungal Agent
6-Prenylindole is a potent antifungal agent derived from the genus Streptomyces. It exhibits significant activity against various fungal strains, making it a valuable compound for antifungal research. Its efficacy in inhibiting fungal growth positions it as a useful tool for studies related to fungal infections and the development of new antifungal therapies. -
Antibiotic
Melithiazole C is an antibiotic that functions as a β-methoxyacrylate (MOA) inhibitor, exhibiting potent antifungal properties. Its biological activity makes it a valuable tool in the study of fungal infections and the development of new antimicrobial treatments. Melithiazole C is suitable for research applications aimed at understanding antifungal mechanisms and therapeutic strategies. -
Antifungal Agent
Indole-3-thio carboxamide is an antifungal agent that functions as a biotransformation product of Camalexin. It has been identified in the context of interactions with the plant pathogenic fungus Botrytis cinerea. This compound is of interest for research applications focusing on antifungal mechanisms and the biochemical pathways involved in plant-fungal interactions. -
Antimicrobial Agent
2-n-Heptyl-4-quinolinol is an antimicrobial agent effective against a range of pathogenic organisms, including Candida albicans, Staphylococcus aureus, and Vibrio species (V. anguillarum and V. harveyi). This compound demonstrates significant antibacterial and antifungal properties, making it a valuable tool for research in microbiology and infectious disease studies. Its mechanism of action involves disruption of microbial membrane integrity and function, contributing to its efficacy as a broad-spectrum antimicrobial reagent. -
Antibiotic
Naphthomycin B is an antibiotic derived from Streptomyces species, targeting bacterial cell wall synthesis. This compound demonstrates significant antimicrobial activity against Gram-positive bacteria and a variety of fungi. It serves as a valuable tool in researching antibacterial and antifungal mechanisms, contributing to the development of novel therapeutic strategies in infectious disease. -
Fungal
Tolciclate is an antifungal agent targeting dermatophytes, demonstrating significant in vitro inhibitory activity at concentrations between 0.01 to 0.1 μg/mL. This compound is characterized by its colorless appearance and solubility in various excipients, with enhanced lipophilicity compared to Tolnaftate. Tolciclate is primarily utilized in research focused on antifungal infections, aiding in the exploration of effective treatments and mechanisms of action against fungal pathogens. -
Anthraquinone Derivative
Neobulgarone F is an anthraquinone derivative derived from Neobulgaria pura HA A07-97, a member of the ascomycetes class of fungi. This compound effectively inhibits the formation of appressoria in Magnaporthe grisea, a key pathogenic fungus in rice. Additionally, Neobulgarone F demonstrates low levels of cytotoxicity while exhibiting no significant antifungal, antibacterial, or phytotoxic effects, making it a valuable tool for research in microbial pathogenesis and plant-fungal interactions. -
Antifungal Agent
Radulone A is a secondary metabolite with antifungal properties, derived from the wood-decomposing fungus Granulobasidium vellereum. This compound effectively inhibits spore germination of notable fungi, including Phlebiopsis gigantea, Coniophora puteana, and Heterobasidion occidentale, at concentrations of 10 µM, 500 µM, and 100 µM, respectively. Radulone A is valuable for research applications related to mycology and the development of antifungal agents. -
Antibiotic
Pyrrolomycin A is a pyrrole antibiotic that exhibits potent antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal effects. It is of interest in research applications focused on antibiotic resistance and the development of new antimicrobial therapies. This compound’s broad-spectrum efficacy makes it valuable for studying microbial infections and potential treatment strategies. -
Antifungal Agent
Torvoside C is a natural compound derived from Solanum torvum, exhibiting potent antifungal activity. This compound demonstrates a broad spectrum of efficacy against various fungi, including Alternaria brassicicola, Alternaria geophila, and Aspergillus flavus, with inhibition zones and minimum inhibitory concentrations ranging from 33.4% to 87.4% and 31.25 to 250 µg/mL, respectively. Torvoside C also effectively inhibits the production of harmful mycotoxins, specifically aflatoxin B1 and fumonisin B1. Its unique properties make it a valuable reagent for research in antifungal infections and mycotoxin-related studies. -
Antibiotic
Aerothionin is an antibiotic that targets bacterial and fungal pathogens, demonstrating potent antimicrobial activity. Additionally, it exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs), making it a valuable compound for oncological research and potential therapeutic applications. -
Antibiotic
Flavomycoin is an antibiotic that exhibits potent antifungal activity. It is primarily utilized in research for its ability to inhibit fungal growth, making it valuable in studies focused on antifungal therapies and infections. This compound serves as a useful tool for investigating mechanisms of action and resistance in fungal pathogens. -
Antifungal Agent
Antifungal Agent 105 is a potent antifungal compound that targets fungal cells, disrupting their integrity and function. It exhibits both protective and curative effects against a variety of fungal pathogens. This agent is useful in research applications focused on mycology, antifungal drug development, and the study of fungal resistance mechanisms. -
Antibiotic
Iodinin is an antibiotic that exhibits both antibacterial and antifungal properties. This compound functions by targeting and inhibiting microbial growth, making it effective in various research applications focused on infection control and microbial resistance. Its dual-action mechanism positions Iodinin as a valuable tool for studies in microbiology and pharmacology. -
Anthracycline Antibiotic
Akrobomycin is an anthracycline antibiotic that primarily targets DNA by intercalating into the double helix, inhibiting topoisomerase II activity. This compound exhibits significant antimicrobial and antitumor properties, making it a valuable tool for cancer research and microbiological studies. Its mechanisms of action and efficacy in disrupting cellular processes position Akrobomycin as a key reagent in the exploration of therapeutic strategies. -
Antibiotic
Melithiazole B is an antibiotic that functions as a β-methoxyacrylate (MOA) inhibitor. It exhibits potent antifungal and cytotoxic activity, making it suitable for research applications in antimicrobial studies and cancer therapeutics. Its dual-action mechanism positions Melithiazole B as a valuable tool in the exploration of novel treatment avenues in both bacterial and fungal infections. -
Fungal Inhibitor
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that functions as a fungal inhibitor. This compound exhibits notable antifungal properties, making it valuable in the study of fungal growth and pathogenicity. It is suitable for research applications focused on fungal diseases and the development of antifungal therapies. -
Botanical Fungicide
4-Propylphenol is a plant-derived phenolic compound that functions as a botanical fungicide. It induces reactive oxygen species (ROS) production in Fusarium graminearum, resulting in DNA and cell membrane damage that effectively inhibits mycelial growth. Additionally, 4-Propylphenol exhibits growth inhibitory effects against walnut pathogenic fungi, such as Colletotrichum gloeosporioides and Alternaria alternata, with an EC50 ranging from 29.11 to 31.89 mg/L, and inhibits spore germination with an EC50 of 55.04-71.85 mg/L. This compound is valuable for research into fungal diseases affecting walnuts and wheat, particularly Fusarium head blight. -
Antibiotic
Neothramycin A is an antibiotic derived from the Streptomyces genus, targeting a broad spectrum of microbial organisms. It demonstrates significant antimicrobial activity against Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) ranging from 25 to 50 μg/mL. Additionally, Neothramycin A exhibits antitumor properties in preclinical models, particularly against leukemia, highlighting its potential for further research in both infectious diseases and cancer therapeutics. -
Antibiotic
Antibiotic AB023a is a macrocyclic pentaene antibiotic that primarily targets fungal organisms. It demonstrates potent antifungal activity against Candida albicans, as well as significant efficacy against plant pathogens including Botrytis cinerea (MIC = 5 μg/mL), Fusarium moniliforme, and Pythium ultimum. This compound is valuable for research applications focused on fungal infections and plant disease prevention. -
Anti-Fungal Agent
Phoslactomycin A is an anti-fungal agent that exhibits potent activity against fungal pathogens. While it demonstrates limited effectiveness against Gram-positive bacteria, its primary application lies in the treatment and study of fungal infections. This compound can be utilized in research focused on understanding fungal biology and developing antifungal therapies. -
Antibiotic
Naphthoquinomycin A is an Ansa antibiotic that exhibits potent antibacterial activity against Gram-positive bacteria and antifungal properties. This compound inhibits the synthesis of fatty acids in E. coli, making it a valuable tool for researching antibiotic resistance mechanisms and developing new antimicrobial therapies. Its diverse biological activities support investigations in microbial pathogenesis and drug development. -
Fungicide
Benalaxyl is a systemic fungicide that inhibits the biosynthesis of fungal cell wall components. It is particularly effective against blue mould caused by Peronospora tubacina, making it a valuable tool in agricultural research aimed at managing this pathogen. Benalaxyl's activity is primarily due to its ability to disrupt fungal growth, providing a basis for studies in plant pathology and disease control strategies. -
Antifungal Agent
AFK-108 is a potent antifungal agent that specifically targets and inhibits the activity of 14 alpha-demethylase. By disrupting ergosterol synthesis, AFK-108 effectively impairs fungal cell membrane integrity, leading to cell death. This compound is suitable for research applications aimed at understanding antifungal mechanisms and developing new therapeutic strategies against fungal infections. -
Fungicide
Pyrazophos is a systemic fungicide primarily targeting powdery mildew pathogens in crops and cereals. It demonstrates effective biological activity against various fungal species, including Erysiphe spp., Sphaerotheca spp., Leveillula spp., and Oidium spp. This reagent is commonly utilized in agricultural research to develop sustainable disease management strategies and enhance crop health. -
Antifungal Agent
Antifungal Agent 146 (Compound 19l) is a broad-spectrum antifungal compound targeting various fungal pathogens. It exhibits significant inhibitory activity against major dermatophytes responsible for onychomycosis, including Trichophyton rubrum and Trichophyton mentagrophytes, as well as other fungi such as Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus, with minimum inhibitory concentration (MIC) values ranging from 16 to 64 μg/mL. This compound is primarily utilized in research focused on fungal infections and their treatment. -
Antimicrobial Agent
5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione functions as an antimicrobial agent. It demonstrates significant activity against various bacteria, including Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and Salmonella typhi, with minimum inhibitory concentrations ranging from 4.5 to 9.9 μM/mL. Additionally, it exhibits antifungal properties, effectively inhibiting Aspergillus niger and Candida albicans at a minimum inhibitory concentration of 4.99 μM/mL. This compound is useful for research in antimicrobial drug discovery and development. -
Antimicrobial Agent
Epicorazine A is an antimicrobial agent that exhibits potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcus (VRE), with minimum inhibitory concentrations (MICs) ranging from 12.5 to 25 μg/mL. Additionally, Epicorazine A demonstrates efficacy against Candida albicans, with an MIC of 25 μg/mL. This compound is suitable for research applications focused on antibacterial and antifungal agents. -
Antibiotic
Melithiazole K is an antibiotic that functions as a β-methoxyacrylate (MOA) inhibitor. It exhibits potent anti-microbial activity, making it a valuable tool in research focused on infectious diseases and the development of novel antibiotics. Its mechanism of action opens avenues for exploring resistance mechanisms and therapeutic efficacy in various bacterial infections. -
Antibiotic
10-Hydroxyundeca-2,4,6,8-tetraynamide is a polyacetylene antibiotic that exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as yeast and fungi. This compound is also noted for its cytotoxic properties, making it a valuable tool in microbiological research and studies of microbial resistance. Its diverse range of biological activities positions it as a candidate for further investigation in the development of new antimicrobial therapies. -
Secondary Metabolites
Byssochlamic acid is a secondary metabolite derived from fungal biosynthetic pathways. This compound exhibits notable biological activity, particularly in antifungal and cytotoxic assays. Its unique properties make it a valuable tool for research in mycology and the investigation of fungal metabolite functions. -
Anti-fungal Agent
2-Ethylbenzimidazole is an anti-fungal agent targeting various fungal species. It effectively inhibits the growth of both unicellular and filamentous fungi, making it a valuable tool in the study of fungal infections. This compound is utilized in research applications aimed at understanding the mechanisms of antifungal activity and developing therapeutic strategies against fungal pathogens. -
CYP51 Inhibitor
Pipercroside B is a potent inhibitor of CYP51, an essential enzyme in sterol biosynthesis. Isolated from Piper crocatum Ruiz & Pav, this compound exhibits significant antifungal activity, making it valuable for research into antifungal therapeutics. Its role in modulating CYP51 provides insights into fungal metabolism and potential treatment strategies against fungal infections. -
Fungal
Benthiavalicarb isopropyl is a fungicide that targets specific fungal pathogens, particularly effective against downy mildew and blight. This compound is utilized in agricultural research to explore alternative strategies for managing serious threats to plant health, especially in potato cultivation. Its application is critical for controlling fungal diseases that are resistant to conventional methods, while studies indicate that environmental and human exposure risks are minimal. -
Anti-Fungal Agent
Crocacin A is an anti-fungal agent that demonstrates inhibitory effects against yeast and filamentous fungi. Additionally, it has the capacity to inhibit the proliferation of mouse fibroblast cell line L929. Mechanistically, Crocacin A disrupts the bc1 complex of the electron transport chain in calf heart microsomes, resulting in a noticeable redshift in the 569 nm peak of the cytochrome B reduction spectrum. This compound is useful for researching fungal infections and exploring mitochondrial function and pathology. -
Antifungal Agent
Antifungal agent 139 targets Colletotrichum gloeosporioides through the inhibition of CgSfu1 and CgRidA. It demonstrates potent antifungal activity by completely blocking mycelial growth, spore germination, and appressorium formation, with an EC50 of 18 μg/mL. This compound effectively prevents the pathogen's infection in susceptible host plants, including linden and cypress trees. Antifungal agent 139 is a valuable tool for research into plant-fungal interactions and disease management strategies.
