Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
2,4-Diacetylphloroglucinol is a polyketide antibiotic that primarily targets a range of pathogenic organisms. This compound demonstrates broad-spectrum antimicrobial activity, effective against bacteria, fungi, oomycetes, and nematodes. Additionally, 2,4-Diacetylphloroglucinol is known to inhibit plant pathogens and can influence root development in tomato seedlings, making it valuable for agricultural research and pathogen control studies. -
Antifungal Potentiator
Polygodial is a sesquiterpene known for its role as an antifungal potentiator. It exhibits significant anti-hyperalgesic properties, making it a valuable compound in research focused on pain modulation and fungal infections. Polygodial has potential applications in developing therapeutic strategies targeting antifungal resistance and enhancing pain relief mechanisms. -
Fluxapyroxad Metabolite
M700F048 is a primary metabolite of the fungicide Fluxapyroxad, targeting the inhibition of succinate dehydrogenase in fungal respiration. This compound is essential for studying the metabolic pathways and environmental behavior of Fluxapyroxad. It has significant applications in toxicological research and understanding the efficacy and degradation of fungicides in agricultural settings. -
Fungicide
Propiconazole is a triazole compound primarily used as a fungicide, targeting fungal sterol biosynthesis by inhibiting the enzyme lanosterol demethylase. Its biological activity is characterized by effective control over various fungal pathogens in agricultural applications. However, it has been identified as a hepatotoxicant and hepatocarcinogen in experimental models, with reported adverse effects on reproduction and development in animals. This information is critical for researchers in toxicology and agricultural sciences assessing the safety and efficacy of fungicidal agents. -
Triazole Fungicide
Difenoconazole is a triazole fungicide that acts as a sterol demethylation inhibitor. It selectively binds to the heme group of fungal cytochrome P450 51, disrupting mycelial growth and inhibiting spore germination. This compound is utilized in research applications focused on pathogenic fungi, offering insights into fungal growth mechanisms and resistance management strategies. -
Parasite Inhibitor
CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, demonstrating IC50 values of 10 nM and 5.0 nM, respectively. In addition, it shows inhibitory activity against Abl and Src kinases with IC50 values of 75 nM and 65 nM. This compound is suitable for research applications related to toxoplasmosis, providing valuable insights into the therapeutic targeting of these pathways. -
Stable Isotope
Loratadine-d5 is a deuterium-labeled derivative of Loratadine, a selective inverse agonist of peripheral histamine H1 receptors. It has demonstrated an IC50 of over 32 μM and exhibits anti-Dengue virus (DENV) activity. Loratadine also inhibits the immunologic release of inflammatory mediators, making Loratadine-d5 a valuable reagent for research in pharmacology and immunology. -
Antifungal Agent
Moracin D is a flavonoid derived from Morus alba, known for its antifungal properties. This compound exhibits significant biological activity, including the induction of cell apoptosis, hypoglycemic effects, and antiadipogenic action. Moracin D is primarily utilized in research involving fungal infections and breast cancer, making it a valuable reagent in the investigation of therapeutic strategies. -
Antifungal Agent
Xanthochymol is an antifungal agent derived from Clusia rosea, primarily targeting fungal cells. This compound demonstrates the ability to induce apoptosis in fungi, making it a valuable tool for investigating fungal cell death mechanisms. It is applicable in research focused on antifungal therapies and the study of fungal pathogen responses to stress. -
Antibiotic
Ascochlorin is an isoprenoid antibiotic that primarily targets the STAT3 signaling cascade, leading to the suppression of tumor growth. It has demonstrated the ability to induce apoptosis in cancer cells while exhibiting anti-inflammatory properties. This compound is valuable for research applications focusing on cancer biology, inflammation, and the modulation of intracellular signaling pathways. -
Cation Ionophore
Calcimycin hemicalcium salt is a potent cation ionophore that primarily facilitates the transport of divalent cations such as calcium and magnesium across cellular membranes. This compound is known to induce Ca2+-dependent cell death by elevating intracellular calcium concentrations, making it valuable for research into apoptosis and autophagy mechanisms. Additionally, Calcimycin hemicalcium salt exhibits antibacterial activity against Gram-positive bacteria and some fungal species, while also inhibiting ATPase activity and uncoupling oxidative phosphorylation in mammalian cells. Its diverse biological effects make it a useful reagent for various biochemical and cellular studies. -
Antifungal Agent
Melittin free acid is a 26-amino-acid polypeptide and a potent activator of phospholipase A2 (PLA2) with significant antifungal activity. It demonstrates broad-spectrum antifungal efficacy, displaying minimum inhibitory concentration (MIC) values between 0.4-60 μM. Melittin free acid exerts its biological effects by promoting fungal cell apoptosis, inhibiting (1,3)-β-D-glucan synthase, and engaging in various other cellular pathways, making it a valuable reagent for research in antifungal mechanisms and therapeutic applications. -
HIV Protease Inhibitor
Indinavir sulfate ethanolate is a selective inhibitor of HIV-1 protease, demonstrating a potent Ki of 0.54 nM for the target enzyme. Beyond its antiviral activity, this compound has shown potential in anticancer research through the inhibition of MMPs-2 activation, anti-angiogenic effects, and promotion of apoptosis. Additionally, Indinavir sulfate ethanolate acts as an inhibitor of the SARS-CoV 3CLpro enzyme, highlighting its diverse biological activity and relevance in multiple research applications. -
Antitumor Antibiotic
Peplomycin is an analog of bleomycin that functions as an antitumor antibiotic. It demonstrates significant antitumor activity while exhibiting lower pulmonary toxicity compared to its parent compound. Peplomycin is known to induce apoptosis in oral squamous cell carcinoma (SSCKN) cells and may lead to skin abnormalities and pulmonary fibrosis. This compound is valuable for research related to tumors, pulmonary fibrosis, and associated diseases. -
HBV Inhibitor
Alisol F 24-acetate is a triterpenoid compound that targets Hepatitis B Virus (HBV) by inhibiting the secretion of HBV surface antigens HBsAg and HBeAg, with respective IC50 values of 7.7 µM and 5.1 µM. This compound also exhibits proapoptotic activity, making it a valuable agent for cancer research applications. Its role in regulating viral antigen secretion positions it as a potential therapeutic candidate in HBV-related studies. -
Photosensitizer
Elsinochrome A is a perylene quinone photosensitizer that generates reactive oxygen species (ROS) upon light excitation, thereby inducing apoptosis and autophagy in targeted cells. This compound demonstrates effective antifungal activity against Candida albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A is suitable for research applications in photodynamic therapy (PDT), particularly with excitation wavelengths around 460 nm. -
Antibiotic Agent
Nargenicin A1 is an antibiotic agent primarily targeting Gram-positive bacteria. It exhibits anti-inflammatory properties and has been shown to protect HINAE cells from DNA damage and apoptosis induced by Tacrolimus. Additionally, Nargenicin A1 is relevant for research applications related to acute myeloid leukemia, making it a valuable compound for studies in both infection and cancer biology. -
Antibiotic
Undecylprodigiosin is an antibiotic derived from the prodiginine family, known for its potent antibacterial properties. It has been shown to selectively induce apoptosis in human breast carcinoma cells independently of the p53 pathway, demonstrating its potential as an anticancer agent. Additionally, undecylprodigiosin possesses immunosuppressive and antimicrobial activities, making it a valuable tool in cancer research and antimicrobial studies. -
Antibacterial Agent
(±)-Trolline, also known as (±)-Oleracein E, is an isoquinoline alkaloid with notable antibacterial properties against respiratory pathogens. Additionally, it demonstrates antiviral activity against influenza viruses A and B. (±)-Trolline is also a potent inducer of hepatic stellate cell apoptosis, making it a valuable tool for studying liver fibrosis and associated liver disorders. -
Antibacterial Growth Promoter
Nitrovin is an antibacterial growth promoter that targets thioredoxin reductase 1 (TrxR1). It acts by inducing reactive oxygen species (ROS)-mediated non-apoptotic and apoptotic-like cell death. Nitrovin exhibits anticancer activity, demonstrating IC50 values ranging from 1.31 to 6.60 μM in various tumor and normal cell lines, making it a valuable tool for research in cancer and antibacterial studies. -
Deuterated Labeled Geraniol (Major)
Geraniol-d6 (Major) is a deuterated form of the terpene compound geraniol, which primarily functions as an olefin. This compound exhibits significant biological activities, including the inhibition of cell proliferation and the promotion of apoptosis. Geraniol-d6 (Major) is valuable for research applications related to diabetes, as well as studies focusing on its antibacterial, antifungal, antioxidant, anti-inflammatory, and antitumor properties. -
Antibiotic
Arisostatin A is a microbial secondary metabolite with antibiotic activity specifically against Gram-positive bacteria. It exhibits potent anti-tumor effects by inducing apoptosis through the activation of caspase-3 and the generation of reactive oxygen species (ROS) in AMC-HN-4 cells. This compound is valuable for research applications in cancer biology and antimicrobial studies. -
Nucleoside Reverse Transcriptase Inhibitor
Stavudine sodium is a nucleoside reverse transcriptase inhibitor (NRTI) primarily utilized for its efficacy against HIV-1 and HIV-2. This compound demonstrates the ability to inhibit mitochondrial DNA replication, reduce NLRP3 inflammasome activation, and modulate the autophagy of Amyloid-β, contributing to its therapeutic potential. Additionally, Stavudine sodium is associated with inducing apoptosis in targeted cells, making it a valuable tool in HIV research and related cellular studies. -
Antibacterial Agent
Antibacterial Agent 292 is a 3-pyrazolylindole derivative targeting bacterial pathogens. This compound exhibits potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC50 values of 2.54 and 3.49 μg/mL, respectively. It suppresses biofilm formation, bacterial motility, and extracellular polysaccharide production while inducing morphological changes and promoting ROS accumulation, leading to bacterial apoptosis. Additionally, it down-regulates genes associated with the type VI secretion system (T6SS), making it a valuable tool for research on rice bacterial blight and citrus canker. -
HSV Inhibitor
Acyclovir hydrochloride is an antiviral agent that specifically targets herpes simplex virus (HSV) replication. It exhibits significant antiherpetic activity, with IC50 values of 0.85 μM for HSV-1 and 0.86 μM for HSV-2. In addition to its antiviral effects, Acyclovir hydrochloride can induce cell cycle disruption and promote apoptosis in infected cells. This compound is also utilized in the context of bacterial infection prevention during induction therapy for acute leukemia. -
Bacterial
(-)-Isoledene primarily functions as an antibacterial agent, exhibiting significant antibacterial and anti-inflammatory activities. This natural organic compound has been investigated for its role in the synthesis of various compound intermediates, highlighting its potential applications in compound development and pharmaceutical research. Its diverse biological activity positions it as a valuable reagent for studies related to bacterial infections and inflammation. -
Antileishmanial Agent
Antileishmanial agent-36 is an indole-dihydropyrimidinone derivative that targets Leishmania species, demonstrating significant anti-leishmanial activity. This compound induces mitochondrial dysfunction through the generation of reactive oxygen species (ROS), leading to apoptosis in infected cells. It exhibits potent lethality against L. donovani with an IC50 value of 4.54 µM, while displaying low cytotoxicity towards J774.1 macrophages. Antileishmanial agent-36 is suitable for research applications focused on visceral leishmaniasis (VL) and parasite burden clearance. -
Bacterial Inhibitor
(Z)-Methyl tetradec-9-enoate functions as a bacterial inhibitor, primarily exerting its cytotoxic effects in human prostate cancer LNCaP cells through the induction of apoptosis and necrosis. Isolated from S. repens fruit extract, this compound also demonstrates antifungal activity, effectively inhibiting the germination of Candida albicans with a minimum inhibitory concentration (MIC) of 9 μM in vivo. Its applications extend to studies in both cancer research and microbiology, making it a valuable reagent for understanding cellular processes and developing therapeutic strategies. -
CYP51 Inhibitor
Antifungal agent 136 is an irreversible inhibitor of fungal lanosterol 14α-demethylase (CYP51). It demonstrates potent antifungal activity against drug-resistant strains of Candida albicans and effectively downregulates IL-6 expression. This compound holds potential for research applications in the fields of fungal infection and inflammatory diseases. -
Antifungal Agent
(E)-2-Octenal is an antifungal agent that disrupts cell membrane integrity and induces reactive oxygen species (ROS) accumulation. It effectively decreases the activity of phosphofructokinase and pyruvate kinase, inhibiting the growth of Neofusicoccum parvum by impairing mitochondrial energy metabolism. Additionally, (E)-2-Octenal demonstrates broad-spectrum efficacy against various fungi, including Sclerotium rolfsii, Metarhizium anisopliae sensu lato, and Aspergillus flavus, making it valuable for research on citrus blue mold and mango stem-end rot. -
Antifungal Agent
Antifungal Agent 152 is an antifungal compound targeting fungal pathogens. It demonstrates significant antifungal activity against Cryptococcus neoformans, Candida albicans, and Candida glabrata, with minimum inhibitory concentrations (MICs) of 4 μg/mL, 16 μg/mL, and 16 μg/mL, respectively. This reagent is useful in research applications focused on fungal infections and therapeutic development. -
Antifungal Antibiotic
Filipin complex is a potent polyene macrolide antifungal antibiotic that primarily targets membrane cholesterol. By inserting into cellular membranes, it sequesters cholesterol, thereby inhibiting the entry of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The complex comprises approximately 75.8% Filipin III, 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I, making it a valuable tool in antifungal research and viral entry studies. Its characteristic fluorescence spectrum (Ex/Em = 380/430 nm) further enhances its utility in biological applications. -
Fungal Inhibitor
Filipin III is a pentaene macrolide antifungal antibiotic featuring a 28-membered ring, primarily derived from various Streptomyces species including S. filipinensis, S. avermitilis, and S. miharaensis. This compound targets membrane sterols, leading to significant alterations in membrane structure, which disrupts fungal cell integrity. Filipin III is widely utilized in research to study fungal infections and to explore mechanisms of antifungal resistance. -
Antibiotic
Nourseothricin sulfate is a broad-spectrum antibiotic that targets the outer membrane of Gram-negative bacteria, effectively disrupting their integrity. This compound inhibits protein biosynthesis in prokaryotic cells and demonstrates significant antifungal activity against eukaryotic organisms. It is widely utilized as a selective marker in various applications, including the transformation of bacteria, yeast, filamentous fungi, and plant cells, facilitating research in microbiology and molecular biology. -
Actin Polymerization Inhibitor
Latrunculin B is an actin polymerization inhibitor commonly derived from marine algae. It modulates the electrophysiological properties of pulmonary veins and has been shown to reduce stretch-induced arrhythmias. Additionally, Latrunculin B exhibits antifungal and antiprotozoal activities, making it a valuable reagent for research in cell biology and pharmacology. -
Fungal Inhibitor
Phenazine-1-carboxylic acid functions as a potent antifungal agent, targeting fungal pathogens effectively. In addition to its antifungal properties, it demonstrates anticancer activity by promoting apoptosis in cancer cells through the modulation of reactive oxygen species (ROS) generation. Phenazine-1-carboxylic acid also influences cytokine expression, upregulating IL-8 and ICAM-1 while inhibiting RANTES and MCP-1 release, indicating potential immunomodulatory effects. This compound is valuable for research in anti-infection strategies, cancer therapy, and immune response modulation. -
Antifungal Agent
Manogepix is a first-in-class, broad-spectrum antifungal agent that acts by inhibiting the biosynthesis of glycosylphosphatidylinositol (GPI) in fungi. This mechanism disrupts essential cellular processes, leading to effective antifungal activity. Researchers can utilize Manogepix for investigating antifungal resistance mechanisms and exploring novel treatment strategies for fungal infections. -
Echinocandin
Rezafungin acetate is a next-generation echinocandin with a broad-spectrum antifungal mechanism, primarily targeting fungal cell wall synthesis. It exhibits strong activity against various pathogens, including Candida spp., Aspergillus spp., and Pneumocystis spp. This compound is valuable for research in antifungal drug development and exploring mechanisms of fungal resistance. -
Antimicrobial Agent
Pyrithione is an antimicrobial agent that primarily inhibits membrane transport processes in fungi. It exhibits potent antibiotic activity against various fungal species, including Penicillium. When incubated with Penicillium mycelia, pyrithione significantly reduces the activity of multiple independently regulated transport systems, making it valuable for research in antifungal mechanisms and microbial resistance studies. -
Fungal
Conalbumin, also known as ovotransferrin, is a monomeric glycoprotein that primarily targets iron transport and is encoded by the avian transferrin gene. This protein, predominantly found in chicken egg white, exhibits a distinct glycosylation pattern that enhances its functionality compared to serum transferrin. Conalbumin demonstrates significant antimicrobial, antifungal, antiviral, anticancer, antioxidative, antihypertensive, and immunoregulatory activities. Its diverse biological properties make it suitable for various research applications, including studies on iron metabolism, and as an ingredient in infant formulas and food additives to promote animal health. -
Fungal Inhibitor
Sakuranetin is a cherry flavonoid phytoalexin that acts as a potent fungal inhibitor. It exhibits strong antifungal properties, along with notable anti-inflammatory and antioxidative activities. Additionally, Sakuranetin has demonstrated efficacy in ameliorating LPS-induced acute lung injury, making it a valuable compound for research in inflammation and respiratory disorders. -
Growth Regulator
Epocholeone is a growth regulator that targets various physiological processes in plants. It exhibits significant efficacy in controlling fungal infections and mitigating physiological diseases in crops, enhancing overall plant health and yield. This compound is ideal for use in agricultural research focusing on plant pathology and growth enhancement strategies. -
Antibiotic
Aurachin D is an antibiotic that primarily targets Gram-positive bacteria and certain fungi. It functions by inhibiting NADH oxidation in beef heart submitochondrial particles, which disrupts cellular respiration and energy production. This compound is valuable for research applications focused on understanding bacterial and fungal resistance mechanisms as well as exploring metabolic pathways. -
Antifungal Agent
T-2307 is an arylamidine with potent antifungal activity, demonstrating efficacy against a wide range of clinically important pathogens. It exhibits broad-spectrum activity with minimum inhibitory concentrations (MIC) ranging from 0.00025 to 0.0078 μg/ml against Candida species, 0.0039 to 0.0625 μg/ml against Cryptococcus neoformans, and 0.0156 to 4 μg/ml against various Aspergillus species. T-2307 is valuable for research applications focused on antifungal development and therapeutic intervention. -
Antifungal Agent
Fosmanogepix is a novel antifungal agent that selectively inhibits the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungal cells. By disrupting the localization of these critical cell wall components, Fosmanogepix compromises fungal cell wall integrity, inhibits biofilm formation, and impedes germ tube morphogenesis, ultimately curtailing fungal growth. This compound is primarily utilized in research focused on invasive fungal infections, offering valuable insights into therapeutic strategies. -
Tropone Derivatives; Tyrosinase Inhibitor; Virus Inhibitor; Funga Inhibitor
Tropolone is a seven-membered non-benzenoid aromatic compound recognized for its role as a tyrosinase inhibitor, exhibiting an IC50 value of 0.4 μM. This compound demonstrates significant anti-viral and anti-fungal properties, making it effective in a variety of therapeutic applications. Additionally, Tropolone shows enhanced effects when used in conjunction with nucleos(t)ide analogs. Its potential for research in osteosarcoma emphasizes its importance in the exploration of new treatments. -
Antifungal Antibiotic/Complex III Inhibitor
Myxothiazol is an antifungal antibiotic that acts as an inhibitor of mitochondrial electron transport chain complex III (bc1 complex). It demonstrates potent antifungal activity against various yeasts and fungi, exhibiting effective growth inhibition at concentrations ranging from 0.01 to 3 μg/ml. This compound is valuable for research applications focused on mitochondrial function and the mechanisms of antifungal resistance. -
Antifungal Cyclic Dipeptide
Cyclo(L-Phe-L-Pro) is an antifungal cyclic dipeptide that selectively targets the retinoic-acid-inducible gene-I (RIG-I) pathway, thereby inhibiting IFN-β production. Isolated from cell-free culture supernatants of Pseudomonas fluorescens and Pseudomonas alcaligenes, this compound demonstrates significant free-radical scavenging ability, with an IC50 of 24 µM in the DPPH assay. It serves as a valuable reagent in studies related to antifungal mechanisms and oxidative stress response. -
Drug Derivative
UDP-rhamnose is the activated form of rhamnose that plays a crucial role in the synthesis of rhamnose-containing glycans in fungi. This nucleotide sugar acts as a key substrate for glycosyltransferases, enabling the assembly of polysaccharides involved in the fungal cell wall. UDP-rhamnose is utilized in research focused on understanding fungal pathogenesis and the development of therapeutics for fungal infections. -
Fungicide
Pyrimethanil is an anilinopyrimidine fungicide that primarily targets the biosynthesis of methionine and other amino acids in Botrytis cinerea. This broad-spectrum contact fungicide effectively controls Botrytis spp. on a variety of crops, including fruits, vegetables, and ornamental plants. Pyrimethanil is utilized in research focused on the prevention of mold infections and the management of fungal diseases in agricultural settings.
