Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Peptide
Astacidin 1 is an antibacterial peptide that exerts its effects through targeted activity against a wide range of bacterial pathogens. Produced via proteolytic cleavage from hemocyanin under acidic conditions, Astacidin 1 demonstrates broad-spectrum antibacterial activity, effectively inhibiting the growth of both Gram-positive and Gram-negative bacteria. This peptide serves as a valuable tool for antimicrobial research and the development of new therapeutic strategies. -
Bacterial Inhibitor
Cephabacin M4 is a cephalosporin derivative, specifically a 7-methoxydesacetylcephalosporin, that functions as a bacterial inhibitor. It exhibits significant antimicrobial activity against a range of bacterial pathogens, making it valuable for research involving antibiotic development and bacterial resistance studies. Isolated from the culture filtrate of Xanthomonas lactamica, Cephabacin M4 serves as a useful tool in exploring cephalosporin efficacy and mechanisms of action. -
Antibacterial Agent
Sampsone B is a dihydrodibenzodioxinone-type antibacterial agent that exhibits activity against methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of ≥128 μg/mL. This compound can be naturally sourced from the aerial parts of Hypericum sampsonii, including its stems and leaves. Sampsone B is valuable for research focused on antibiotic resistance and the development of new antibacterial therapies. -
Anti-Mycobacterial Agent
BM635 mesylate is an MmpL3 inhibitor exhibiting potent anti-mycobacterial activity. It demonstrates a MIC50 of 0.6 μM against Mycobacterium tuberculosis H37Rv, highlighting its efficacy in combating tuberculosis. The mesylate form enhances bioavailability compared to the free-base variant, making it a significant candidate for tuberculosis research applications. -
Bacterial
AHU1 is a specific inhibitor of Shiga toxin type 2 expression in Escherichia coli O157:H7, exerting its effects through the modulation of the SOS response via interactions with the RecA protein. This compound demonstrates a dose-dependent reduction in toxin activity, making it a valuable tool for studying bacterial toxin regulation and pathogenesis. AHU1 is suitable for research applications focused on bacterial infections and microbial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 121 primarily targets bacterial infections as a potent antibacterial agent. It exhibits significant anti-mycobacterial properties along with anti-inflammatory effects, making it valuable in the study of tuberculosis (TB). This compound is especially relevant for research focused on developing new therapeutic strategies for bacterial infections and understanding inflammation-related mechanisms associated with TB. -
Antibacterial Agent
Ashimycin A is a Streptomyces-derived antibiotic that exhibits broad-spectrum antibacterial activity. It targets bacterial cell wall synthesis, making it effective against various gram-positive and gram-negative bacteria. This compound is primarily used in research focused on antimicrobial resistance, providing insights into potential new therapeutic strategies. -
Antibacterial Agent
α/β-Hydrolase-IN-1 is a potent antibacterial agent that demonstrates effective inhibitory activity against key mycobacterial strains. It exhibits minimum inhibitory concentrations (MICs) of 50 μM against Mycobacterium smegmatis and 16 μM against Mycobacterium tuberculosis H37Ra. This compound serves as a valuable tool for researching antibacterial mechanisms and developing new therapies targeting mycobacterial infections. -
Antibacterial Agent
Sulfaperin, also known as Methylsulfadiazin, functions as an antibacterial agent by inhibiting bacterial folic acid synthesis. This compound demonstrates effective activity against a broad spectrum of Gram-positive and Gram-negative bacteria. It is commonly utilized in microbiological research and studies focused on antibiotic resistance mechanisms. -
Antimicrobial
4-Ethoxycoumarin is a coumarin derivative with demonstrated antimicrobial activity. It exerts its effects by targeting and inhibiting microbial growth, making it valuable for research into antibacterial and antifungal mechanisms. This compound is frequently utilized in studies assessing the efficacy of antimicrobial agents and investigating potential therapeutic applications in infectious diseases. -
Anticancer/antibacterial/antimalarial Agent
25-Hydroperoxycycloart-23-en-3β-ol is a multifunctional compound with notable anticancer, antibacterial, and antimalarial properties. Isolated from Blepharodon nitidum, it demonstrates significant cytotoxic effects against various tumor cell lines, including large cell lung cancer, melanoma, colon adenocarcinoma, and chronic myelogenous leukemia. Additionally, this compound exhibits anti-Mycobacterium tuberculosis and antileishmanial activities, making it a valuable tool for research in cancer therapeutics and infectious disease studies. -
Bacterial
Antibacterial agent 72 selectively targets bacterial membranes, exerting potent antibacterial activity. This compound can be utilized in research applications focused on bacterial pathogenesis, resistance mechanisms, and the development of novel antimicrobial therapies. Its mechanism of action makes it a valuable tool in understanding bacterial cell integrity and function. -
Antibacterial Agent
Antibacterial agent 86 (Compound A11) functions as a potent bacteriostatic agent against methicillin-resistant Staphylococcus aureus (MRSA). It exhibits exceptional activity with minimum inhibitory concentration (MIC) values as low as 0.00191 μg/mL, outperforming traditional antibiotics such as tiamulin and retapamulin by 162 and 32 times, respectively. This compound is suitable for research applications focusing on antibiotic resistance and the development of new therapeutic strategies against MRSA infections. -
Antibacterial Agent
E-3709 is an antibacterial agent that targets Gram-positive bacteria. It demonstrates potent inhibitory activity against a range of pathogens, including Staphylococcus aureus (MRSA), Enterococcus faecalis, various streptococci, Clostridia, and diphtheroids. This compound is suitable for research applications focused on Gram-positive bacterial infections, providing valuable insights into potential therapeutic strategies. -
Antibacterial Agent
Neoabietic acid is an abietic-type acid derived from the oleoresin and rosin of Pinus palustris, exhibiting significant antibacterial properties. Its mechanism involves the disruption of bacterial cell membranes, leading to cell death. This compound is valuable in research focused on antibacterial agents and their potential applications in drug development and infection control. -
Anti-tuberculosis Drug
MMV676584 is an investigational anti-tuberculosis drug that demonstrates inhibitory activity against Mycobacterium tuberculosis. This compound exhibits potential as a therapeutic agent for the treatment of eumycetoma, a chronic fungal infection. Its ability to combat tuberculosis positions MMV676584 as a promising candidate for further research in anti-infective therapies. -
Antibiotic
2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic that targets bacterial replication. It demonstrates lethal activity against specific strains of Escherichia coli, with its antibacterial effects reversible by guanosine and other purine nucleosides. This compound is suitable for studying bacterial infections and understanding the mechanisms of antibiotic resistance. -
Metallo-β-lactamase Inhibitor
Metallo-β-lactamase-IN-16 is a potent metallo-β-lactamase inhibitor targeting critical enzymes responsible for antibiotic resistance. This sulfone-containing compound shows significant antibacterial activity by effectively inhibiting NDM-1, IMP-1, VIM-1, and VIM-2, with IC50 values of 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM, respectively. It serves as a valuable tool for research in combating bacterial infections and understanding the mechanisms of antibiotic resistance. -
Antimycobacterial Agent
AB131 is a potent inhibitor of MSMEG 6649 and Rv2172c, with dissociation constants (Kd) of 0.16 μM and 0.02 μM, respectively. This compound enhances the efficacy of antitubercular agents, making it a valuable tool for researchers studying antimycobacterial mechanisms. Its ability to sensitize mycobacterial infections presents potential applications in therapeutic development and drug resistance studies. -
Antibacterial Agent
Antibacterial Agent 59 is a potent antibacterial compound that targets a range of bacterial strains. It demonstrates significant antibacterial activity, making it suitable for research applications focused on infection control and the development of new antimicrobial therapies. This reagent provides valuable insights into the mechanisms of bacterial resistance and can aid in the discovery of novel antibiotics. -
Bacterial Inhibitor
Antibacterial agent 202 (compound 45c) is a bacterial inhibitor that targets Gram-negative bacteria, demonstrating significant antibacterial activity against strains such as Escherichia coli, Klebsiella pneumoniae, and especially Pseudomonas aeruginosa, with a minimum inhibitory concentration (MIC) ranging from 7.8 to 31.25 μM. This compound functions by disrupting the integrity of bacterial cell membranes, making it a valuable tool for research into bacterial infections and potential therapeutic applications. -
Antibacterial Agent
Antibacterial Agent 49 targets bacterial pathogens, exhibiting potent antimicrobial properties. This compound demonstrates significant activity against a range of Gram-positive and Gram-negative bacteria, making it valuable for research in infectious disease and antibiotic resistance. Its efficacy in disrupting bacterial growth positions it as a promising candidate for the development of new antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 40 is a potent antibacterial compound that targets bacterial cell wall synthesis, leading to disruption of cellular integrity. This agent exhibits significant activity against a broad spectrum of bacterial pathogens, making it valuable for research in antibiotic development and the study of bacterial resistance mechanisms. It is useful for evaluating the efficacy of new antibacterial treatments and understanding bacterial biology. -
Bacterial
Cefbuperazone sodium is a broad-spectrum antibacterial agent targeting various bacterial infections. It exhibits potent antimicrobial activity and a linear pharmacokinetic profile, ensuring reliable dosing parameters in clinical applications. Following intravenous administration, Cefbuperazone sodium achieves peak plasma concentrations, reflecting its rapid absorption and distribution. The compound is primarily eliminated unchanged through the renal system, underscoring its effectiveness in treating infections. -
Antibacterial Agent
Antibacterial Agent 107 is a potent antibacterial compound primarily targeting Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 1.56 μg/mL. This agent exhibits low hemolytic activity and high membrane selectivity, demonstrating rapid bactericidal effects. Additionally, Antibacterial Agent 107 has shown effective in vivo efficacy in murine models of bacterial keratitis caused by Staphylococcus aureus ATCC29213, highlighting its potential for therapeutic applications in bacterial infections. -
Antibacterial Agent
4'-O-Methyl-8-prenylnaringenin is a prenylated flavonoid known for its antibacterial activity. It enhances cell penetration and disrupts bacterial cell membranes or walls, effectively targeting various bacteria. Minimum inhibitory concentrations (MICs) have been reported as 32 μg/mL for Staphylococcus aureus and Bacillus subtilis, and 128 μg/mL for Pseudomonas aeruginosa, highlighting its potential for research applications in antimicrobial studies. -
Antibacterial agent
FtsZ-IN-9 is an antibacterial agent targeting the essential protein FtsZ, which is critical for bacterial cell division. By specifically inhibiting the assembly of Mycobacterium smegmatis FtsZ (MsFtsZ), FtsZ-IN-9 disrupts bacterial proliferation. This compound is valuable for research focused on developing novel antimicrobial therapies and understanding bacterial cell division mechanisms. -
Bacterial Inhibitor
BPH-651 is a bacterial inhibitor that targets dehydrosqualene synthase, an essential enzyme involved in bacterial terpenoid biosynthesis. This compound exhibits potent antibacterial activity by binding to multiple sites on the enzyme, revealing structural insights into the mechanism of action and inhibition of head-to-head prenyltransferase. BPH-651 is useful for research focused on designing new antibacterial agents and studying bacterial resistance mechanisms. -
Bacterial Inhibitor
Antistaphylococcal agent 1 functions as a bacterial inhibitor, specifically targeting Staphylococcus species. This compound exhibits significant antimicrobial activity, making it a valuable tool in the study of bacterial infections and resistance mechanisms. Its application can aid in the development of novel therapeutic strategies against staphylococcal infections. -
Anti-Bacterial Agent
Furanomycin is an anti-bacterial agent that exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria. This compound inhibits the bacteriophage of Escherichia coli and acts as a competitive antagonist of L-isoleucine, making it a valuable tool for exploring bacterial resistance mechanisms and characterizing amino acid transport pathways. Its diverse biological activity supports a range of research applications in microbiology and antibiotic discovery. -
Anti-bacterial Agent
8-Br-GTP is a GTP analog that serves as a competitive inhibitor of FtsZ polymerization and GTPase activity, exhibiting a Ki value of 31.8 μM. This compound demonstrates antibacterial properties and can be utilized for nucleic acid modification in various research applications, particularly in the study of bacterial cell division and antibiotic resistance mechanisms. -
Antibacterial Agent
ATD-3169 is an antibacterial agent that functions by enhancing endogenous reactive oxygen species (ROS), including superoxide radicals. This mechanism of action effectively inhibits the growth of Mycobacterium tuberculosis (Mtb). ATD-3169 is a valuable tool for research applications aimed at understanding and combating tuberculosis infections. -
Bacterial Inhibitor
(Rac)-DNDI-8219 is a bacterial inhibitor with demonstrated efficacy against Leishmania species. This compound exhibits potent antituberculosis and anti-leishmanial activities, showcasing significant effectiveness in both the Leishmania donovani mouse model and the Leishmania infantum hamster model. Interestingly, the R-6 candidate form of (Rac)-DNDI-8219 offers excellent oral bioavailability and efficacy in the hamster model, making it a valuable tool for research focused on treating leishmaniasis and tuberculosis. -
Antibacterial Agent
CYP3A4 enzyme-IN-1 is a potent antibacterial agent that specifically targets and inhibits bacterial growth, demonstrating a minimum inhibitory concentration (MIC) of 1 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA). Additionally, this compound exhibits low to moderate inhibitory effects on various cytochrome P450 enzymes, including CYP1A2, CYP2E1, CYP2D6, and CYP3A4. It serves as a valuable tool for studying antibacterial mechanisms and exploring potential therapeutic applications in infectious diseases. -
Antibacterial Agent
Armeniaspirol A is an antibacterial agent that targets the cell membranes of Helicobacter pylori. It induces membrane permeabilization, leading to cytoplasmic leakage and effectively inhibits or eradicates biofilm formation. This compound shows promise for research related to H. pylori infections and contributes to understanding strategies for combating this pathogen. -
Antibacterial Agent
Jinflexin D is a dimeric phenanthrene natural product that functions as a potential antibacterial agent. Its unique seven-membered ring structure enhances its biological activity, although it does not exhibit inhibitory effects against methicillin-resistant Staphylococcus aureus (MRSA). Extracted from the methanol extract of the roots of Juncus inflexus, Jinflexin D may have applications in the development of novel antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 47 acts primarily as an antibacterial compound, enhancing the efficacy of established antibiotics such as Ceftazidime. This agent significantly lowers the minimum inhibitory concentration (MIC) of Ceftazidime, promoting greater antibacterial activity against susceptible strains. Antibacterial Agent 47 is suitable for research focused on developing combination therapies and investigating mechanisms of antibiotic resistance. -
Antibacterial Agent
Daldinone A is an antibacterial agent isolated from Nigrospora oryzae, targeting a range of microbial pathogens. Notably, Daldinone A exhibits significant antimicrobial activity against Pseudomonas aeruginosa, making it a valuable compound for research in antimicrobial resistance and drug development. Its potential applications extend to exploring new therapeutic strategies for treating bacterial infections. -
Antibacterial Agent
Hexahydrohippuric acid is an antibacterial agent derived from the microbial metabolism of shikimic acid in liver and kidney tissues. This compound consists of cyclohexane carboxylic acid and glycinamide, exhibiting significant antibacterial activity. Its unique properties make it a valuable tool for research into antibacterial mechanisms and potential therapeutic applications. -
Antibacterial Agent
(+)-Thienamycin is a potent broad-spectrum antibacterial agent and β-lactamase inhibitor derived from Streptomyces cattleya. It demonstrates significant activity against various Gram-positive and Gram-negative bacteria, making it a valuable tool for research in antimicrobial resistance and antibiotic development. Its ability to inhibit β-lactamase enzymes enhances the efficacy of β-lactam antibiotics, facilitating studies on bacterial pathogenesis and therapeutic strategies. -
Antibacterial Agent
RWJ-416457 is an orally bioavailable antibacterial agent that targets 23S rRNA within the ribosome. This compound exhibits potent activity against Gram-positive bacterial infections, making it a valuable tool for researchers studying antibiotic mechanisms and bacterial resistance. Its specific action on ribosomal components positions RWJ-416457 as an important candidate for further exploration in antimicrobial research. -
Bacterial
FCE 22250 is a 3-azinomethylrifamycin that targets bacterial infections, demonstrating long-term in vivo persistence and effective oral absorption. It exhibits potent antimicrobial activity across a broad spectrum, particularly against mycobacteria, making it a valuable reagent for research applications focused on bacterial resistance and treatment strategies. -
Antibacterial Drug
Curcapicycloside (Pilosidine) is a norlignan glucoside that exhibits antibacterial activity primarily targeting Escherichia coli. This compound has potential applications in antibacterial drug development and pharmacological studies aimed at understanding its mechanisms of action against bacterial infections. It serves as a valuable tool for researchers investigating novel antibacterial agents. -
Antibacterial Agent
Mucrolidin is an eudesmane-type sesquiterpenoid with antibacterial activity. Isolated from the aerial parts of Homalomena occulta, Mucrolidin demonstrates modest efficacy against bacterial strains. This compound can be used in research applications focusing on the development of new antibacterial agents and the study of natural product pharmacology. -
Bacterial Inhibitor
Acaterin is a bacterial inhibitor derived from Pseudomonas, known for its role in antimicrobial activity. Research indicates that its biosynthesis is regulated through a complex gene cluster, with studies highlighting its associated biosynthetic pathway. Comparative transcriptomics further demonstrates the compound's formation is intricately linked to bacterial regulatory networks, making it valuable for studies in bacterial physiology and the development of new antimicrobial strategies. -
Antibacterial Agent
Antibacterial Agent 102 is a potent antibacterial compound that exhibits significant in vitro and in vivo activity against Staphylococcus aureus, with minimum inhibitory concentrations (MICs) below 0.5 μg/mL. Additionally, it moderately inhibits the cytochrome P450 enzyme CYP3A4, with an IC50 value of 6.148 μM. This compound has demonstrated efficacy in reducing Methicillin-resistant Staphylococcus aureus (MRSA) loads in infected mice models, making it valuable for research into antibiotic resistance and therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 201 is an antibacterial compound that disrupts membrane integrity in target organisms. It demonstrates significant efficacy against Staphylococcus aureus strain RN4220, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa strain PA01, and Escherichia coli strain ANS1, with minimum inhibitory concentrations (MIC99) of 2.0, 1, 8.1, and 2.2 μg/mL, respectively. This reagent is suitable for research applications focused on studying bacterial resistance mechanisms and evaluating antibacterial properties. -
Antibacterial Agent
Antibacterial Agent 48 is a potent antibacterial compound that enhances the efficacy of the beta-lactam antibiotic Ceftazidime by significantly reducing its minimum inhibitory concentration (MIC). This synergy suggests its potential utility in combating antibiotic-resistant bacterial strains and improving treatment outcomes. It is a valuable reagent for research focused on developing novel antibacterial therapies and exploring resistance mechanisms. -
Antimycobacterial Agent
Antimycobacterial agent-1 selectively targets Mycobacterium tuberculosis (M. tuberculosis) H37Ra and exhibits potent antimycobacterial activity with a minimum inhibitory concentration (MIC) of 1 μg/ml. This compound demonstrates relatively low cytotoxicity in normal cells, as evidenced by an IC50 value of 143.2 μg/ml in Vero cells. Its efficacy and safety profile make it a valuable tool for research focused on tuberculosis and antimycobacterial drug development. -
Antibacterial Agent
Antibacterial Agent 94 is a potent antibacterial compound that demonstrates significant activity against MRSA persisters. This agent disrupts bacterial membrane integrity and interferes with the synthesis of phosphatidylglycerol (PG). Its mechanism of action makes it a valuable tool in the research of antibacterial therapies and the exploration of drug resistance in pathogenic bacteria.
