Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Antibacterial Agent 35 is an antibacterial compound that enhances the efficacy of Ceftazidime by significantly lowering its minimum inhibitory concentration (MIC) value. This synergy suggests its potential role in combating resistant bacterial strains. Antibacterial Agent 35 is suitable for research applications focused on antibiotic susceptibility and the development of combination therapies. -
β-lactamase Inhibitor
rel-Avibactam sodium is a potent β-lactamase inhibitor designed to combat bacterial resistance. It demonstrates broad-spectrum antibacterial activity, particularly against Enterobacteriaceae that produce Ambler A and C types of β-lactamases. When used in combination with Cefazidime, rel-Avibactam sodium exhibits significant inhibitory effects and offers enhanced efficiency compared to traditional β-lactamase inhibitors, as indicated by its low IC50 values against TEM-1 and P99 enzymes. This compound is essential for research into antibiotic resistance and the development of novel antibacterial therapies. -
Antibacterial Compound
Viroxocin is a diterpenoid with antibacterial properties. Isolated from the roots of Salvia viridis L. cvar. Blue Jeans, Viroxocin exhibits weak antibacterial activity, making it a candidate for research in antimicrobial studies. This compound can be utilized to explore its potential effects in drug development and infectious disease research. -
Anti-mycobacterial Agent
Calpinactam (FKI-4905) is a fungal metabolite with potent anti-mycobacterial activity. It selectively inhibits the growth of Mycobacterium species, specifically demonstrating minimum inhibitory concentration (MIC) values of 0.78 μg/ml against Mycobacterium smegmatis and 12.5 μg/ml against Mycobacterium tuberculosis. This compound is primarily utilized in research applications focused on developing treatments for mycobacterial infections. -
Antibacterial Agent
Antibacterial Agent 12 is a biaryloxazolidinone analogue that targets bacterial ribosomes to inhibit protein synthesis. This compound exhibits potent antibacterial activity against both antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria. It is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 219 is an antibacterial compound that disrupts cell wall biosynthesis. It demonstrates potent activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with a minimum inhibitory concentration (MIC) ranging from 0.5 to 32 µg/mL, as well as Enterococcus faecium and S. aureus, both with an MIC of 2 µg/mL. This compound is valuable for research related to antibiotic resistance and the development of new antibacterial therapies. -
Bacterial Inhibitor
Antibacterial Agent 240 (compound 62-7c) is a bacterial inhibitor specifically designed to target multidrug-resistant (MDR) strains of Methicillin-resistant Staphylococcus aureus (MRSA). This compound demonstrates significant antibacterial efficacy, as evidenced by its potent anti-infection activity in preclinical mouse models of pneumonia and wound infections caused by MRSA. Its favorable biosafety profile further supports its potential use in therapeutic applications against resistant bacterial infections. -
Antibacterial Agent
Dodicin hydrochloride is a potent antibacterial agent targeting a wide range of microbial organisms. Known for its broad-spectrum antimicrobial activity, it is utilized in various research applications focused on infection control and the development of disinfectants. This compound is suitable for studies exploring mechanisms of antibacterial action and evaluating efficacy against resistant strains. -
Bacterial Penicillin-binding Protein (PBPs) Inhibitor
J-114870 is an inhibitor of bacterial penicillin-binding proteins (PBPs), demonstrating significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS). This compound is valuable for research applications focused on bacterial infections, particularly in understanding resistance mechanisms and developing new therapeutic strategies. -
Bacterial Inhibitor
Antistaphylococcal agent 2 is a bacterial inhibitor targeting Staphylococcus species. It exhibits potent antimicrobial activity, making it effective in combating staphylococcal infections. This compound is primarily utilized in research applications aimed at understanding and developing therapies for bacterial resistance and infection control. -
Antibacterial Agent
Antibacterial Agent 290 is a sulfonamide derivative known for its primary mechanism as an antibacterial agent. This compound exhibits antiproliferative activity against a range of tumor cells and significantly activates the E3 ligase Parkin, inducing auto-ubiquitination with an EC50 of 0.4 μM. Antibacterial Agent 290 is applicable in the synthesis of building blocks for supramolecular structures, including metal-organic frameworks and coordination polymers. Its utility extends to research in cancer, neurological disorders, and infectious diseases. -
Antibacterial Agent
Lucidin ω-ethyl ether is an anthraquinone metabolite that exhibits antibacterial activity by targeting the bacterial cell structure. Isolated from the root of Prismatomeris filamentosa, it demonstrates efficacy against both Gram-positive and Gram-negative bacteria. This compound is useful for research applications in microbial studies and the development of antibacterial agents. -
Antibacterial Agent
L-693989 is an orally active water-soluble lipopeptide that functions as an antibacterial agent. It exhibits significant anticandidal and antipneumocystis activity, effectively preventing the development of P. carinii cysts. This compound shows promise for research applications related to P. carinii pneumonia, contributing to studies focused on combating opportunistic infections. -
Anti-bacterial Agent
Talaromycesone A is an oxaphenalenone dimer with significant antibacterial properties, exhibiting an IC50 of 3.70 μM against Staphylococcus strains pathogenic to humans. Additionally, it demonstrates strong inhibition of acetylcholinesterase with an IC50 of 7.49 μM. This compound is valuable for research applications focusing on antimicrobial susceptibility and neuropharmacology. -
Antibacterial Agent
Antibacterial Agent 52 functions as a broad-spectrum antibacterial agent. It exhibits significant inhibitory activity against various bacterial strains, showcasing potential for studying bacterial resistance mechanisms and evaluating new therapeutic strategies. This compound is suitable for applications in microbiological research and drug development aimed at combating bacterial infections. -
Bacterial Inhibitor
Antibacterial agent 31 is a bacterial inhibitor that demonstrates significant antibacterial activity against rice bacterial leaf streak. This compound is essential for research applications focused on plant pathology and the development of disease-resistant agricultural practices. Its mechanism of action provides insights into bacterial resistance mechanisms and potential strategies for crop protection. -
Antibacterial Agent
3,4-Dihydroxyallylbenzene 3,4-di-O-glucoside is a phenylpropanoid glycoside known for its antibacterial properties. Isolated from the dragon’s blood of Dracaena cambodiana, this compound demonstrates significant activity against various bacterial strains. It serves as a valuable research tool for studies focused on antibacterial mechanisms and the development of antimicrobial agents. -
Antibacterial Agent
Rosellichalasin is an antibacterial agent derived from the endophytic fungus Aspergillus flavipes Y-62. It demonstrates significant antibacterial activity, making it a valuable compound for research in antibacterial applications and the study of microbial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 50 is an effective antibacterial compound primarily targeting Gram-negative bacteria. It exhibits minimum inhibitory concentration (MIC) values of 32 mcg/mL, 64 mcg/mL, and 128 mcg/mL against various Escherichia coli strains, including NCTC 13351, M 50, and 7 MP. This agent is relevant for research applications focused on evaluating antibacterial efficacy and mechanisms of resistance in bacterial pathogens. -
Antibacterial Agent
Antibacterial Agent 54 functions primarily as an antibacterial agent, exhibiting effective inhibition of bacterial growth. This compound is derived from natural sources and offers robust activity against a range of pathogenic bacteria. Its application in research includes the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
Antibacterial agent 249 is a bacterial inhibitor that exhibits broad-spectrum antimicrobial properties. It effectively inhibits the growth of various pathogens including Aspergillus niger, Bacillus subtilis, Pseudomonas albicans, Escherichia coli, and Staphylococcus aureus. Additionally, it displays anti-inflammatory activity in vitro, highlighting its potential applications in the treatment of bacterial infections. -
Antibacterial Agent
2',3'-Dehydrosalannol is a potent antibacterial agent that exhibits strong activity against a range of bacteria including Klebsiella pneumoniae ATCC 13883, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25922, Escherichia coli ATCC 11775, and Enterococcus faecalis ATCC 10541. It displays minimum inhibitory concentration (MIC) values of 0.78, 1.56, 1.56, 6.25, and 25 μg/mL, respectively. This compound is valuable for research applications focusing on antibacterial drug development and microbiological studies. -
Antibacterial Agent
Antibacterial Agent 38 is a novel antibacterial compound that selectively targets bacterial pathogens. It exhibits significant antimicrobial activity, making it suitable for research on bacterial infections and the development of new therapeutic strategies. This compound represents a promising tool for investigating the mechanisms of bacterial resistance and evaluating the efficacy of antimicrobial agents. -
Cephalosporin Prodrug
Cefcanel daloxate is a cephalosporin prodrug that exhibits antibacterial activity primarily against Gram-positive bacteria and Haemophilus influenzae. As an orally active compound, it has potential applications in research related to uremia, helping to elucidate mechanisms of infection and treatment strategies in affected patients. -
Anti-Bacterial Agent
Rhodirubin B is an anti-bacterial agent primarily targeting Gram-positive bacteria and exhibiting activity against Mycobacterium species. This compound has demonstrated the ability to enhance survival rates in mice inoculated with leukemia L-1210, indicating potential applications in cancer research and infectious disease studies. Rhodirubin B is valuable for investigating mechanisms of bacterial resistance and the interplay between infection and cancer. -
Bacterial Inhibitor
Kipukasin D is a natural nucleoside derived from Aspergillus versicolor, exhibiting potent antibacterial activity. It operates primarily as a bacterial inhibitor, making it valuable for research involving bacterial infections and microbial resistance mechanisms. This compound is useful for studies in pharmacology, microbiology, and drug development focused on identifying new antimicrobial agents. -
Bacterial Inhibitor
Antistaphylococcal agent 3 is a bacterial inhibitor that targets Staphylococcus species, disrupting their growth and proliferation. This compound exhibits potent antimicrobial activity, making it suitable for research applications focused on bacterial infection models and therapeutic development. Its efficacy against resistant strains renders it valuable for studies aimed at understanding staphylococcal pathogenesis and developing novel antibacterial strategies. -
Anti-Bacterial Agent
Rhodirubin A is an anti-bacterial agent primarily targeting Gram-positive bacteria and demonstrating efficacy against Mycobacterium species. In addition to its antibacterial properties, Rhodirubin A has been shown to extend the survival time in mice models inoculated with leukemia L-1210. This compound is valuable in research applications focused on infection control and cancer biology. -
Bacterial Inhibitor
DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections. -
Bacterial Inhibitor
Urechistachykinin I is a tachykinin-related peptide derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating no hemolytic effects, making it a valuable reagent for research into antimicrobial mechanisms and agents. Its unique properties make it suitable for studies investigating bacterial inhibition in various biological contexts. -
Antibacterial/Anti-inflammatory Agent
Antibacterial Agent 115 is a potent antibacterial and anti-inflammatory compound. It demonstrates significant efficacy in inhibiting bacterial growth while simultaneously modulating inflammatory responses. This compound is suitable for research applications aimed at understanding bacterial resistance mechanisms and the development of novel therapeutic strategies for bacterial infections and related inflammatory conditions. -
Anti-bacterial Agent
Antibacterial Agent 204 (Compd P2-56-3) is an anti-bacterial agent that exhibits enhanced Rifampin activity against Acinetobacter baumannii and Klebsiella pneumoniae. This compound disrupts the outer membrane of A. baumannii, which contributes to its antimicrobial efficacy. Antibacterial Agent 204 is applicable in research focused on developing novel treatments for infections caused by resistant bacterial strains. -
Antibacterial Agent
Antibacterial agent 82 (compound 7p) functions as an antibacterial agent targeting bacterial growth and proliferation. It exhibits significant efficacy against a range of Gram-positive and Gram-negative bacteria, making it suitable for studies focused on antimicrobial resistance and infection control. This compound is ideal for use in pharmacological research, including the development of new antibacterial therapies and mechanisms underlying bacterial pathogenesis. -
Antibacterial Compound
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound known for its effectiveness against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting minimum inhibitory concentration (MIC) values of 4-32 μg/mL. Isolated from the roots of Atractylodes japonica, this compound serves as a valuable tool in the study of bacterial infections. Additionally, it functions as a click chemistry reagent due to its alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. -
Antifouling/Antibacterial Agent
Cochliomycin A is an antifouling and antibacterial agent derived from the Gorgonian-Derived Fungus Cochliobolus lunatus. It exhibits significant antifouling activity, with an EC50 of 1.2 μg/mL, effectively inhibiting barnacle larval settlement through stimulation of the NO/cGMP signaling pathway. Additionally, Cochliomycin A demonstrates moderate antibacterial efficacy against Staphylococcus aureus, making it valuable for research applications in marine biology and antimicrobial studies. -
Antibacterial Agent
Trospectomycin dihydrochloride is an antibacterial agent targeting bacterial ribosome function. This compound demonstrates broad-spectrum activity against various gram-positive and gram-negative bacteria. Trospectomycin dihydrochloride is suitable for research applications involving the study of bacterial infections and the evaluation of antibiotic resistance mechanisms. -
Antibacterial Agent
Furaltadone is a nitrofuran derivative that acts as an antibacterial agent primarily targeting gram-positive bacteria. It demonstrates both inhibitory and bactericidal effects against staphylococci in vitro. This compound is particularly relevant for research on bacterial infections, including those caused by Salmonella enteritidis in poultry, offering insights into its therapeutic potential in veterinary medicine. -
Antibacterial Agent
Armeniaspirol C is a potent antibacterial agent that specifically targets Gram-positive bacteria. This compound demonstrates significant efficacy against multidrug-resistant strains, making it a valuable candidate for research into infections caused by resistant Gram-positive pathogens. Its unique mechanism of action positions Armeniaspirol C as a promising tool for the development of new antibacterial therapies. -
Antibiotic
Amythiamicin C is an antimicrobial antibiotic that primarily targets Gram-positive bacteria, including strains of methicillin-resistant Staphylococcus aureus (MRSA). Additionally, it exhibits activity against Plasmodium falciparum, making it valuable for research in infectious diseases and antibiotic resistance. This compound is relevant for studies focused on the development of novel therapeutic strategies against resistant bacterial infections and malaria. -
Antibiotic
A51493A is an anthracyclinone antibiotic that exhibits potent antimicrobial activity against Gram-positive bacteria. This compound is useful in research applications focused on bacterial infections and exploring mechanisms of antibiotic resistance. Its unique structure and mode of action make it a valuable tool for studying antimicrobial efficacy and developing new therapeutic strategies. -
Antibiotic
Seldomycin factor 1 is an aminoglycoside antibiotic that targets bacterial protein synthesis. It exhibits a broad spectrum of antimicrobial activity against various Gram-positive and Gram-negative bacteria. This compound is valuable for research applications in microbiology and antibiotic resistance studies. -
Antibiotic
Chitinovorin C is a β-lactam antibiotic that primarily targets bacterial cell wall synthesis. It exhibits selective inhibitory activity against Gram-negative bacteria, making it a valuable tool in antibiotic research. This compound is utilized in studies aimed at understanding antibiotic resistance mechanisms and developing new therapeutic strategies against bacterial infections. -
Antibiotic
Spectinomycin sulfate hydrate is an antibiotic that primarily targets bacterial ribosomes to inhibit protein synthesis. It demonstrates broad-spectrum activity against various gram-positive and gram-negative organisms, making it a valuable tool in microbiological research. Additionally, Spectinomycin sulfate hydrate acts as a noncompetitive inhibitor of td intron RNA, with a reported Ki value of 7.2 mM, further expanding its utility in molecular biology studies. -
Antibiotic
Parvodicin B1 is a glycopeptide antibiotic that exerts its antimicrobial effects by inhibiting bacterial cell wall synthesis. It demonstrates significant activity against Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus, and Enterococcus faecalis. Parvodicin B1 is valuable in microbiological research and antibiotic susceptibility studies, providing insights into bacterial resistance mechanisms and antibiotic efficacy. -
Antibiotic
Sch 29482 is an orally active penem antibiotic that exhibits broad-spectrum antibacterial activity. This compound demonstrates effectiveness against a variety of Gram-positive and Gram-negative bacteria, making it a valuable tool for research into antibacterial treatments. Its unique mechanism of action interferes with bacterial cell wall synthesis, providing insights into antibiotic efficacy and resistance mechanisms. -
Antibiotic
Methacycline is a tetracycline antibiotic that primarily inhibits bacterial protein synthesis. It is recognized for its capacity to impede epithelial-to-mesenchymal transition (EMT) in vitro and to inhibit fibrogenesis in vivo, functioning independently of TGF-β1 Smad signaling pathways. Methacycline serves as an antimicrobial agent and demonstrates potential applications in the study of pulmonary fibrosis. -
Antibiotic
Pristinamycin II B is an ester peptide antibiotic that primarily targets Gram-positive bacteria. It exhibits potent antibacterial activity, making it a valuable reagent in studies focused on the treatment of infections caused by resistant strains. This compound is commonly utilized in research applications related to antibiotic resistance and the development of novel antimicrobial therapies. -
Antibiotic
Helvolinic acid is a steroidal antibiotic that targets Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool in the study of antimicrobial mechanisms and the development of new therapeutic agents. Its efficacy against resistant strains of bacteria positions it as a noteworthy reagent in antibiotic research and development. -
Antitumor Antibiotic
Menoxymycin B is an antitumor antibiotic that exhibits notable cytotoxic effects against cancer cells. It demonstrates potent inhibitory activity with IC50 values of 0.22 μM in KB cells and 0.023 μM in N18-RE-105 cells. This compound is valuable for cancer research, particularly in studies focused on cell proliferation and apoptosis mechanisms. -
Antibiotic
Minosaminomycin is an antibiotic that targets bacterial cells and is derived from the bacterium Streptomyces No. MA514A1. This compound demonstrates significant antimicrobial activity against Mycobacterium smegmatis ATCC 607 and Mycobacterium phlei, with minimum inhibitory concentrations (MIC) of 1.56 μg/mL and 6.25 μg/mL, respectively. Minosaminomycin is valuable for research applications focused on bacterial infections and the study of mycobacterial resistance.
