Antifection

Isavuconazole is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Ascomycin is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. It has been researched for the treatment of autoimmune diseases and skin diseases, and to prevent rejection after an organ transplant.

Enfuvirtide Acetate (T-20) is a 36 amino acid peptide corresponding to a region of gp41, the transmembrane subunit of HIV-1 envelope protein.

The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. Rifamycin S is found to be very active against gram positive bacteria, with minimum inhibitory concentration being 0.0025 /ug/ml.

Presatovir is a novel, orally bioavailable RSV fusion inhibitor, against a wide range of RSV A and B clinical isolates (mean EC50 = 0.43 nM).

Calicheamicin is an potent enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora. Calicheamicin targets DNA and cause strand scission.

Dalbavancin is a novel second-generation lipoglycopeptide antibiotic.

GSK2838232-isomer is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection.

Tildipirosin is a novel 16-membered-ring macrolide authorized for the treatment of bovine and swine respiratory disease.

Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.

Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.

Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.

Nitrofurantoin is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.

Furazolidone is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.

GSK744 is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.

BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of >90 μM.

Chlorothricin is a spirotetronic acid antibiotic inhibitor of pyruvate carboxylase.

Ansatrienin B is an ansamycin antibiotic that contains a triene structure.

Povidone iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine.

Cefmenoxime Hydrochloride is a cephalosporin antibiotic that is administered intravenously or intramuscularly.

Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.

Sodium Sulfadiazine is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments.

L-ornithine has an antifatigue effect in increasing the efficiency of energy consumption and promoting the excretion of ammonia.

Dapsone is a synthetic derivative of diamino-sulfone with anti-inflammatory and anti-bacterial properties, commonly used for the treatment of leprosy.

Butylparaben is a chemical compound commonly used as an antifungal preservative in cosmetic products.

Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.

Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.

Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.

Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, beta-lactam antibiotic.

Azithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.

Azlocillin is an acylampicillin with a broad spectrum against bacteria.

Carsalam is a nonsteroidal anti-inflammatory drug.

Ceftriaxone sodium trihydrate is a third-generation cephalosporin antibiotic.

Cefuroxime Sodium is a cephalosporin effective against gram-positive and gram-negative bacteria with resistance to beta-lactamase.

Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.

Chlorquinaldol is an antimicrobial agent used for local antisepsy.

Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.

Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.

Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.

Clopidol is an organic compound that is used as in veterinary medicine, as a coccidiostat.

Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.

Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.

Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis drug.

Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.

Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi.

Spiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens.

Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part.