Antifection

Items 251-300 of 4946

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  1. Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria.
  2. Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.
  3. Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan.
  4. Flavin Mononucleotide (FMN) Inhibitor

    Ribocil B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
  5. HIV replication inhibitor

    ABX-464, also known as SPL-464, is an inhibitor of the HIV replication potentially for the treatment of HIV infection.
  6. 7-Amino-4-methylcoumarin is a fluorogenic reagent and antibacterial, antifungal agent. It os used as reference compound in enzyme assays.
  7. Sulfalene is an antimalarial agent.
  8. dipeptidase inhibitor

    Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.
  9. anthelmintic

    Oxyclozanide is a salicylanilide anthelmintic that is a proton ionophore which uncouples oxidative phosphorylation of the target organism.
  10. CYP51 inhibitor

    Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi.
  11. Antibiotic

    Sulfaquinoxaline sodium salt is an antibiotic which has activity against a broad spectrum of Gram-negative and Gram-positive bacteria.
  12. Antibiotic

    Robenidine hydrochloride is an antibiotic used for the control of coccidiosis, a debilitating protozoal infection in poultry.
  13. Antibacterial

    Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone.
  14. antimicrobial compound

    Antibiotic-5d is a synthesis and antimicrobial compound.
  15. Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.
  16. Monobehenin has a strong inhibitory activity toward bacterial biofilm formation.
  17. RLR agonist

    KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.
  18. LpxC inhibitor

    ACHN-975 is a selective LpxC inhibitor, exhibiting a subnanomolar LpxC inhibitory activity and low MIC values (≤1 μg/mL) against a wide range of Gram-negative bacteria.

  19. Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics that is being developed for the treatment of eye infections.
  20. antibacterial agent

    BMY-43748 is a promising antibacterial agent, exhibiting great in vitro and in vivo antibacterial activity.
  21. KB-5246 is a tetracyclic quinolone and displays antibacterial activities.
  22. Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3 μM.
  23. N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic.
  24. HIV protease inhibitor

    DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
  25. HIV protease inhibitor

    Darunavir is an HIV protease inhibitor
  26. UL97 kinase inhibitor

    Maribavir is an UL97 kinase inhibitor potentially for the treatment of cytomegalovirus (CMV) infection. The mechanism by which maribavir inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97.
  27. HIV-1 capsid CTD dimerization inhibitor

    Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity .
  28. CYP51 inhibitor

    Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.
  29. Cefiderocol (S-649266) is a novel siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
  30. Hetacillin potassium is a broad-spectrum treatment for use against a wide range of common Gram-positive and Gram-negative bacteria.
  31. D77

    anti-HIV-1 inhibitor

    D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
  32. AVX 13616 shows the potent in vivo antibacterial activity of Avexa??s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.
  33. Piperazine Citrate is an organic compound that consists of a six-membered ring, containting two nitrogen atoms at opposite positions in the ring; first introduced in 1953 as an Anthelmintic.
  34. Fabl inhibitor

    AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ??0.12 μg/ml.
  35. Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
  36. Tubulysin A(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.
  37. G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
  38. Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine.
  39. Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia.
  40. Methasulfocarb is a fungicide compound.
  41. Ridinilazole is a novel antibacterial with MICs range of 0.06-0.25??g/mL (MIC90=8??g/mL) against C.?difficile.
  42. diazabicyclooctane inhibitor

    Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.
  43. Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
  44. Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation.
  45. FabI enzyme inhibitor

    MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively.
  46. Meptyldinocap (2,4-DNOPC) is a novel powdery mildew (Erysiphe necator) fungicide which shows protectant and post-infective activities.
  47. Flumorph(SYP-L190) is a carboxylic acid amide (CAA) fungicide.
  48. Penthiopyrad(MTF-753) is a carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps; inhibits fungal respiration by binding to mitochondrial respiratory complex II.
  49. Valifenalate(IR5885; Valiphenal), which is approved for application on high-value crops such as grapes, tomatoes and other vegetables, is effective against various types of mildew and is currently marketed primarily under the Valis moniker; insecticide agent.
  50. Tiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; fungicide.

Items 251-300 of 4946

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