Biological Activity
Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.96 mL | 94.81 mL | 189.61 mL |
0.5 mM | 3.79 mL | 18.96 mL | 37.92 mL |
1 mM | 1.9 mL | 9.48 mL | 18.96 mL |
5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A20838 |
---|---|
CAS No. | 1340593-59-0 |
Formula | C23H16F7N5O2 |
M. Wt | 527.39 |
Solubility | DMSO |
Purity | >98% |
Synonyms | VT-1161, VT1161, VT 1161 |
SMILES | O[[email protected]@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OCC(F)(F)F)C=C4)C=N3)F |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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