G-418 disulfate

Catalog No.: A21002

G-418 disulfate

G-418 disulfate Chemical Structure

CAS NO. 108321-42-2

G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

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500 mg
$45.00
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Biological Activity

G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
In vitro (25°C) DMSO Insoluble
Water Warmed: 92 mg/mL (132.81 mM)
Ethanol Insoluble
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.44 mL 72.18 mL 144.36 mL
0.5 mM 2.89 mL 14.44 mL 28.87 mL
1 mM 1.44 mL 7.22 mL 14.44 mL
5 mM 0.29 mL 1.44 mL 2.89 mL

*The above data is based on the productmolecular weight 692.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21002
CAS No. 108321-42-2
Formula C20H44N4O18S2
M. Wt 692.71
Solubility DMSO
Purity >98%
Synonyms Geneticin sulfate; Antibiotic G-418 sulfate, G418, G 418
SMILES O=S(O)(O)=O.O[[email protected]@H]([[email protected]@H]1O[[email protected]@]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]2O)N)([H])O[[email protected]]2([H])[[email protected]](O)C)[[email protected]]([[email protected]@H](C[[email protected]@H]1N)N)O[[email protected]](OC[[email protected]](C)(O)[[email protected]@H]3NC)([H])[[email protected]@H]3O.O=S(O)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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