AFN-1252

Catalog No.: A20981

Fab inhibitor

AFN-1252

AFN-1252 Chemical Structure

CAS NO. 620175-39-5

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ??0.12 μg/ml.

Availability: In stock

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5 mg

Regular Price: $162.00

Special Price $129.60

10 mg

Regular Price: $279.00

Special Price $223.20

50 mg

Regular Price: $828.00

Special Price $662.40

100 mg

Regular Price: $1,656.00

Special Price $1,324.80

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Biological Activity

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ??0.12 μg/ml.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.18 mL 266.37 mL
0.5 mM 5.33 mL 26.64 mL 53.27 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20981
Actions Inhibitor
CAS No. 620175-39-5
Formula C22H21N3O3
M. Wt 375.42
Purity >98%
Synonyms API-1252, API1252, API 1252; Debio 1452, Debio1452, Debio-1452, AFN1252, AFN 1252
SMILES O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C(C=C3CC4)=CNC3=NC4=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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