Ebselen

Catalog No.: A20834

HIV-1 capsid CTD dimerization inhibitor

Ebselen

Ebselen Chemical Structure

CAS NO. 60940-34-3

Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity .

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$78.00
50 mg
$230.00
100 mg
$460.00
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Biological Activity

Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity .
In vitro DMSO 52 mg/mL (189.65 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.47 mL 182.35 mL 364.7 mL
0.5 mM 7.29 mL 36.47 mL 72.94 mL
1 mM 3.65 mL 18.23 mL 36.47 mL
5 mM 0.73 mL 3.65 mL 7.29 mL

*The above data is based on the productmolecular weight 274.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20834
Actions Inhibitor
CAS No. 60940-34-3
Formula C13H9NOSe
M. Wt 274.2
Purity >98%
Synonyms SPI1005, SPI 1005, SPI-1005, PZ-51, PZ 51, PZ51, CCG-39161, CCG39161, CCG 39161
SMILES O=C1N(C2=CC=CC=C2)[Se]C3=C1C=CC=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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