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Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity .
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.47 mL | 182.35 mL | 364.7 mL |
| 0.5 mM | 7.29 mL | 36.47 mL | 72.94 mL |
| 1 mM | 3.65 mL | 18.23 mL | 36.47 mL |
| 5 mM | 0.73 mL | 3.65 mL | 7.29 mL |
*The above data is based on the productmolecular weight 274.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20834 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 274.2 |
| Formula | C13H9NOSe |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 60940-34-3 |
| Synonyms | SPI1005, SPI 1005, SPI-1005, PZ-51, PZ 51, PZ51, CCG-39161, CCG39161, CCG 39161 |
| SMILES | O=C1N(C2=CC=CC=C2)[Se]C3=C1C=CC=C3 |
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