Antifection

Spiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens.

Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part.

Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria.

Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.

Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan.

Ribocil B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.

7-Amino-4-methylcoumarin is a fluorogenic reagent and antibacterial, antifungal agent. It os used as reference compound in enzyme assays.

Sulfalene is an antimalarial agent.

Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.

Oxyclozanide is a salicylanilide anthelmintic that is a proton ionophore which uncouples oxidative phosphorylation of the target organism.

Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi.

Sulfaquinoxaline sodium salt is an antibiotic which has activity against a broad spectrum of Gram-negative and Gram-positive bacteria.

Robenidine hydrochloride is an antibiotic used for the control of coccidiosis, a debilitating protozoal infection in poultry.

Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone.

Aminoacyl tRNA synthetase-IN-1, is a bacterial aminoacyl tRNA synthetase (aaRS) inhibitor.

Vibunazole is an antifungal agent.

KIN-1148, a small-molecule IRF3 agonist, functions as an influenza vaccine adjuvant by modulating the antiviral immune response.

Cinchonine prevents High-Fat-Diet-Induced Obesity through downregulation of Adipogenesis and Adipose inflammation.

Cefadroxil, also known as Duricef, is an antibiotic effective against pyodermic skin diseases, such as Staphylococcus aureus and Streptococcus pyogenes.

Cefamandole nafate is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole nafate is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Turimycin is a macrolide antibiotic that is effective against a wide spectrum of pathogens.

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria.

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics.

Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.

Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic similar in nature to chloral hydrate.

Sulfachlorpyridazine, also known as Sonilyn, Cluricol, Durasulf, and Ba 10370, is an antibacterial agent typically used in agricultural practices.

Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.

Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

Procaine hydrochloride is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.

Piromidic acid is antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.

Cinoxacin was an older synthetic antimicrobial related to the quinolone class of antibiotics with activity similar to oxolinic acid and nalidixic acid.

Phthalylsulfacetamide is an antibiotic sulfonamide used as a leprostatic agent to treat urinary tract infections.

Cephapirin Sodium is the sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, first-generation cephalosporin antibiotic. It is beta-lactam with bactericidal activity. Cephalosporin antibiotic is effective against gram-negative and gram-positive organisms. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units.

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It is only functional against Gram-positive bacteria, It penetrates into human lung tissue.

Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells.

Cefuroxime axetil is a second generation cephalosporin antibiotic with a broad spectrum activity against Gram positive and Gram negative bacteria.

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations.

Cefoxitin Sodium is a semisynthetic cephamycin antibiotic resistant to beta-lactamase. It is derived from Cephamycin C and is highly resistance to β-lactamase inactivation.

Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity.

Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.

Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. It is used as a coccidiostat for poultry.

Sulfamethoxazole sodium is an antibiotic used for bacterial infections.

Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity.

Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity.

Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity.

Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis.

Sorbic acid is a mold and yeast inhibitor. Used as a fungistatic agent for foods, especially cheeses.

Cefotetan Hydrochloride is a second-generation cephalosporin that is active against some strains of β-lactamase producing bacteria. It shows anti-microbial activity against Gram-positive and Gram-negative bacteria; it is more efficacious against Gram-negative and anaerobic bacteria

Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.